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Q9T1T5 (LYS_BPAPS) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable lysozyme

EC=3.2.1.17
Alternative name(s):
Endolysin
Lysis protein
Muramidase
P13
Gene names
Name:13
OrganismAcyrthosiphon pisum secondary endosymbiont phage 1 (Bacteriophage APSE-1) [Complete proteome]
Taxonomic identifier67571 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stageCaudoviralesPodoviridae
Virus hostEscherichia coli [TaxID: 562]

Protein attributes

Sequence length146 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Essential for lysis of bacterial cell wall, by showing cell wall hydrolyzing activity By similarity.

Catalytic activity

Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

Sequence similarities

Belongs to the glycosyl hydrolase 24 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 146146Probable lysozyme
PRO_0000218091

Sites

Active site151Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9T1T5 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: AF9689BC02218086

FASTA14616,330
        10         20         30         40         50         60 
MHISEKGLVL IKRYEGLRLK AYQCRAGRWT LGYGHTHNLN IGDVITQEQA EAFLREDIAQ 

        70         80         90        100        110        120 
VTALLNTQIK VPLTQNQYDA ICSLVFNIGM TAFTTSTLLK KLNVGDYSGA SAEFMKWSKA 

       130        140 
KVNGKRTPLP GLIKRRQAEK ALFESA 

« Hide

References

[1]"Isolation and characterization of APSE-1, a bacteriophage infecting the secondary endosymbiont of acyrthosiphon pisum."
van der Wilk F., Dullemans A.M., Verbeek M., van den Heuvel J.F.J.M.
Virology 262:104-113(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF157835 Genomic DNA. Translation: AAF03956.1.
RefSeqNP_050974.1. NC_000935.1.

3D structure databases

ProteinModelPortalQ9T1T5.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH24. Glycoside Hydrolase Family 24.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1262307.

Family and domain databases

Gene3D1.10.530.40. 1 hit.
InterProIPR002196. Glyco_hydro_24.
IPR023346. Lysozyme-like_dom.
IPR023347. Lysozyme_dom.
[Graphical view]
PfamPF00959. Phage_lysozyme. 1 hit.
[Graphical view]
SUPFAMSSF53955. SSF53955. 1 hit.
ProtoNetSearch...

Entry information

Entry nameLYS_BPAPS
AccessionPrimary (citable) accession number: Q9T1T5
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 2000
Last modified: May 14, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries