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Protein

Probable lysozyme

Gene

13

Organism
Acyrthosiphon pisum secondary endosymbiont phage 1 (Bacteriophage APSE-1)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Essential for lysis of bacterial cell wall, by showing cell wall hydrolyzing activity.By similarity

Catalytic activityi

Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei15Proton donorBy similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase

Protein family/group databases

CAZyiGH24. Glycoside Hydrolase Family 24.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable lysozyme (EC:3.2.1.17)
Alternative name(s):
Endolysin
Lysis protein
Muramidase
P13
Gene namesi
Name:13
OrganismiAcyrthosiphon pisum secondary endosymbiont phage 1 (Bacteriophage APSE-1)
Taxonomic identifieri67571 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesPodoviridae
Virus hostiEscherichia coli [TaxID: 562]
Proteomesi
  • UP000000853 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002180911 – 146Probable lysozymeAdd BLAST146

Structurei

3D structure databases

ProteinModelPortaliQ9T1T5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 24 family.Curated

Phylogenomic databases

KOiK01185.

Family and domain databases

CDDicd00737. endolysin_autolysin. 1 hit.
Gene3Di1.10.530.40. 1 hit.
InterProiIPR033907. Endolysin_autolysin.
IPR002196. Glyco_hydro_24.
IPR023346. Lysozyme-like_dom.
IPR023347. Lysozyme_dom.
[Graphical view]
PfamiPF00959. Phage_lysozyme. 1 hit.
[Graphical view]
SUPFAMiSSF53955. SSF53955. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9T1T5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHISEKGLVL IKRYEGLRLK AYQCRAGRWT LGYGHTHNLN IGDVITQEQA
60 70 80 90 100
EAFLREDIAQ VTALLNTQIK VPLTQNQYDA ICSLVFNIGM TAFTTSTLLK
110 120 130 140
KLNVGDYSGA SAEFMKWSKA KVNGKRTPLP GLIKRRQAEK ALFESA
Length:146
Mass (Da):16,330
Last modified:May 1, 2000 - v1
Checksum:iAF9689BC02218086
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF157835 Genomic DNA. Translation: AAF03956.1.
RefSeqiNP_050974.1. NC_000935.1.

Genome annotation databases

GeneIDi1262307.
KEGGivg:1262307.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF157835 Genomic DNA. Translation: AAF03956.1.
RefSeqiNP_050974.1. NC_000935.1.

3D structure databases

ProteinModelPortaliQ9T1T5.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGH24. Glycoside Hydrolase Family 24.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1262307.
KEGGivg:1262307.

Phylogenomic databases

KOiK01185.

Family and domain databases

CDDicd00737. endolysin_autolysin. 1 hit.
Gene3Di1.10.530.40. 1 hit.
InterProiIPR033907. Endolysin_autolysin.
IPR002196. Glyco_hydro_24.
IPR023346. Lysozyme-like_dom.
IPR023347. Lysozyme_dom.
[Graphical view]
PfamiPF00959. Phage_lysozyme. 1 hit.
[Graphical view]
SUPFAMiSSF53955. SSF53955. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiLYS_BPAPS
AccessioniPrimary (citable) accession number: Q9T1T5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 2000
Last modified: November 30, 2016
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.