Q9SZE7 (PER51_ARATH) Reviewed, UniProtKB/Swiss-Prot
Last modified
December 14, 2011.
Version 97.
History...
Names·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Peroxidase 51 Short name=Atperox P51 EC=1.11.1.7 Alternative name(s): ATP37 | ||||||||
| Gene names |
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| Organism | Arabidopsis thaliana (Mouse-ear cress) | ||||||||
| Taxonomic identifier | 3702 [NCBI] | ||||||||
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Protein attributes
| Sequence length | 329 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Function | Removal of H2O2, oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue. |
| Catalytic activity | 2 phenolic donor + H2O2 = 2 phenoxyl radical of the donor + 2 H2O. |
| Cofactor | Binds 1 heme B (iron-protoporphyrin IX) group per subunit By similarity. Binds 2 calcium ions per subunit By similarity. |
| Subcellular location | Secreted By similarity. |
| Miscellaneous | There are 73 peroxidase genes in A.thaliana. |
| Sequence similarities | Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Hydrogen peroxide |
| Cellular component | Secreted |
| Coding sequence diversity | Alternative splicing |
| Domain | Signal |
| Ligand | Calcium Heme Iron Metal-binding |
| Molecular function | Oxidoreductase Peroxidase |
| PTM | Disulfide bond Glycoprotein Pyrrolidone carboxylic acid |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | hydrogen peroxide catabolic process Inferred from electronic annotation. Source: UniProtKB-KW response to salt stressInferred from expression pattern. Source: TAIR |
| Cellular component | extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | heme binding Inferred from electronic annotation. Source: InterPro peroxidase activityInferred from electronic annotation. Source: UniProtKB-KW protein bindingInferred from physical interaction. Source: TAIR |
| Complete GO annotation... | |
Alternative products
| This entry describes 1 isoform produced by alternative splicing. [Select] Note: A number of isoforms are produced. According to EST sequences. | ||||||
| Isoform 1 (identifier: Q9SZE7-1) This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||||
Molecule processing | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal peptide | 1 – 25 | 25 | Potential | ||||||||
| Chain | 26 – 329 | 304 | Peroxidase 51 | PRO_0000023716 | |||||||
Sites | |||||||||||
| Active site | 67 | 1 | Proton acceptor By similarity | ||||||||
| Metal binding | 68 | 1 | Calcium 1 By similarity | ||||||||
| Metal binding | 71 | 1 | Calcium 1; via carbonyl oxygen By similarity | ||||||||
| Metal binding | 73 | 1 | Calcium 1; via carbonyl oxygen By similarity | ||||||||
| Metal binding | 75 | 1 | Calcium 1 By similarity | ||||||||
| Metal binding | 77 | 1 | Calcium 1 By similarity | ||||||||
| Metal binding | 197 | 1 | Iron (heme axial ligand) By similarity | ||||||||
| Metal binding | 198 | 1 | Calcium 2 By similarity | ||||||||
| Metal binding | 249 | 1 | Calcium 2 By similarity | ||||||||
| Metal binding | 252 | 1 | Calcium 2 By similarity | ||||||||
| Metal binding | 257 | 1 | Calcium 2 By similarity | ||||||||
| Binding site | 167 | 1 | Substrate; via carbonyl oxygen By similarity | ||||||||
| Site | 63 | 1 | Transition state stabilizer By similarity | ||||||||
Amino acid modifications | |||||||||||
| Modified residue | 26 | 1 | Pyrrolidone carboxylic acid By similarity | ||||||||
| Glycosylation | 215 | 1 | N-linked (GlcNAc...) Potential | ||||||||
| Disulfide bond | 36 ↔ 119 | By similarity | |||||||||
| Disulfide bond | 69 ↔ 74 | By similarity | |||||||||
| Disulfide bond | 125 ↔ 325 | By similarity | |||||||||
| Disulfide bond | 204 ↔ 236 | By similarity | |||||||||
Experimental info | |||||||||||
| Sequence conflict | 31 | 1 | F → L in AAL49862. Ref.4 | ||||||||
Sequences
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References
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AF469928 mRNA. Translation: AAL79842.1. AL035601 Genomic DNA. No translation available. AL035605 Genomic DNA. Translation: CAB38292.1. AL161591 Genomic DNA. Translation: CAB80418.1. CP002687 Genomic DNA. Translation: AEE86806.1. AY070459 mRNA. Translation: AAL49862.1. AY150515 mRNA. Translation: AAN13031.1. |
| IPI | IPI00540304. |
| PIR | T04710. |
| RefSeq | NP_195469.1. NM_119917.2. |
| UniGene | At.68229. |
3D structure databases | |
| ProteinModelPortal | Q9SZE7. |
| SMR | Q9SZE7. Positions 26-329. |
| ModBase | Search... |
Protein-protein interaction databases | |
| IntAct | Q9SZE7. 1 interaction. |
Protein family/group databases | |
| PeroxiBase | 217. AtPrx51. |
Proteomic databases | |
| PRIDE | Q9SZE7. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblPlants | AT4G37530.1; AT4G37530.1; AT4G37530. |
| GeneID | 829908. |
| GenomeReviews | Gene locus AT4G37530 in contig CT486007_GR. |
| KEGG | ath:AT4G37530. |
| NMPDR | fig|3702.1.peg.21864. |
Organism-specific databases | |
| GeneFarm | 1883. 61. |
| TAIR | At4g37530. |
Phylogenomic databases | |
| GeneTree | EPGT00050000003677. |
| HOGENOM | HBG597790. |
| InParanoid | Q9SZE7. |
| PhylomeDB | Q9SZE7. |
| ProtClustDB | CLSN2685802. |
Gene expression databases | |
| ArrayExpress | Q9SZE7. |
| Genevestigator | Q9SZE7. |
| GermOnline | AT4G37530. Arabidopsis thaliana. |
Family and domain databases | |
| InterPro | IPR010255. Haem_peroxidase. IPR002016. Haem_peroxidase_pln/fun/bac. IPR000823. Peroxidase_pln. IPR019793. Peroxidases_heam-ligand_BS. [Graphical view] |
| KO | K00430. |
| Pfam | PF00141. peroxidase. 1 hit. [Graphical view] |
| PRINTS | PR00458. PEROXIDASE. PR00461. PLPEROXIDASE. |
| SUPFAM | SSF48113. Peroxidase_super. 1 hit. |
| PROSITE | PS00435. PEROXIDASE_1. 1 hit. PS00436. PEROXIDASE_2. False negative. PS50873. PEROXIDASE_4. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | PER51_ARATH | ||||||||
| Accession | Primary (citable) accession number: Q9SZE7 Secondary accession number(s): Q8VYK8 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Plant Protein Annotation Program | ||||||||
Relevant documents
| Arabidopsis thaliana Arabidopsis thaliana: entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with