Reviewed,
UniProtKB/Swiss-Prot Q9SZB9 (PER47_ARATH)
Last modified
June 16, 2009.
Version 65.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Peroxidase 47 Short name=Atperox P47 EC=1.11.1.7 Alternative name(s): ATP32 | ||||||||
| Gene names |
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| Organism | Arabidopsis thaliana (Mouse-ear cress) [Complete proteome] | ||||||||
| Taxonomic identifier | 3702 [NCBI] | ||||||||
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis |
Protein attributes
| Sequence length | 314 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Function | Removal of H2O2, oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue. |
| Catalytic activity | Donor + H2O2 = oxidized donor + 2 H2O. |
| Cofactor | Binds 1 heme B (iron-protoporphyrin IX) group per subunit By similarity. Binds 2 calcium ions per subunit By similarity. |
| Subcellular location | Secreted By similarity. |
| Developmental stage | Up-regulated during leaf development. Ref.3 |
| Miscellaneous | There are 73 peroxidase genes in A.thaliana. |
| Sequence similarities | Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Secreted |
| Domain | Signal |
| Ligand | Calcium Heme Iron Metal-binding |
| Molecular function | Oxidoreductase Peroxidase |
| PTM | Disulfide bond Glycoprotein |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW response to oxidative stressInferred from electronic annotation. Source: InterPro |
| Cellular component | extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | calcium ion binding Inferred from electronic annotation. Source: UniProtKB-KW electron carrier activityInferred from electronic annotation. Source: InterPro heme bindingInferred from electronic annotation. Source: InterPro peroxidase activityInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||||
Molecule processing | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal peptide | 1 – 25 | 25 | Potential | ||||||||
| Chain | 26 – 314 | 289 | Peroxidase 47 | PRO_0000023713 | |||||||
Sites | |||||||||||
| Active site | 66 | 1 | Proton acceptor By similarity | ||||||||
| Metal binding | 67 | 1 | Calcium 1 By similarity | ||||||||
| Metal binding | 72 | 1 | Calcium 1; via carbonyl oxygen By similarity | ||||||||
| Metal binding | 74 | 1 | Calcium 1 By similarity | ||||||||
| Metal binding | 76 | 1 | Calcium 1 By similarity | ||||||||
| Metal binding | 191 | 1 | Iron (heme axial ligand) By similarity | ||||||||
| Metal binding | 192 | 1 | Calcium 2 By similarity | ||||||||
| Metal binding | 235 | 1 | Calcium 2 By similarity | ||||||||
| Metal binding | 237 | 1 | Calcium 2 By similarity | ||||||||
| Metal binding | 242 | 1 | Calcium 2 By similarity | ||||||||
| Binding site | 161 | 1 | Substrate; via carbonyl oxygen By similarity | ||||||||
| Site | 62 | 1 | Transition state stabilizer By similarity | ||||||||
Amino acid modifications | |||||||||||
| Glycosylation | 166 | 1 | N-linked (GlcNAc...) Potential | ||||||||
| Disulfide bond | 35 ↔ 114 | By similarity | |||||||||
| Disulfide bond | 68 ↔ 73 | By similarity | |||||||||
| Disulfide bond | 120 ↔ 310 | By similarity | |||||||||
| Disulfide bond | 198 ↔ 224 | By similarity | |||||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Structural diversity and transcription of class III peroxidases from Arabidopsis thaliana." Welinder K.G., Justesen A.F., Kjaersgaard I.V.H., Jensen R.B., Rasmussen S.K., Jespersen H.M., Duroux L. Eur. J. Biochem. 269:6063-6081(2002) [PubMed: 12473102] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Columbia. |
| [2] | "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana." Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B. McCombie W.R.Nature 402:769-777(1999) [PubMed: 10617198] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia. |
| [3] | "Toward elucidating the global gene expression patterns of developing Arabidopsis: parallel analysis of 8300 genes by a high-density oligonucleotide probe array." Zhu T., Budworth P., Han B., Brown D., Chang H.-S., Zou G., Wang X. Plant Physiol. Biochem. 39:221-242(2001) Cited for: DEVELOPMENTAL STAGE. Strain: cv. Columbia. |
| [4] | "Analysis and expression of the class III peroxidase large gene family in Arabidopsis thaliana." Tognolli M., Penel C., Greppin H., Simon P. Gene 288:129-138(2002) [PubMed: 12034502] [Abstract] Cited for: GENE FAMILY ORGANIZATION, NOMENCLATURE. Strain: cv. Columbia. |
Cross-references
Sequence databases | |
|---|---|
| AF451951 mRNA. Translation: AAL40837.1. AL035678 Genomic DNA. Translation: CAB38800.1. AL161583 Genomic DNA. Translation: CAB80059.1. | |
| IPI | IPI00539387. |
| PIR | T05993. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1QGJ based on UniProtKB Q39034. |
| ModBase | Search... |
Protein family/group databases | |
| PeroxiBase | 213. AtPrx47. |
Proteomic databases | |
| PRIDE | Q9SZB9. |
Genome annotation databases | |
| GenomeReviews | Gene locus AT4G33420 in contig CT486007_GR. |
| NMPDR | fig|3702.1.peg.21384. |
Organism-specific databases | |
| GeneFarm | 1879. 61. |
| TAIR | At4g33420. |
Enzyme and pathway databases | |
| BRENDA | 1.11.1.7. 302. |
Gene expression databases | |
| GermOnline | AT4G33420. Arabidopsis thaliana. |
Family and domain databases | |
| InterPro | IPR002016. Haem_peroxidase_pln/fun/bac. IPR000823. Peroxidase_pln. IPR019794. Peroxidases_AS. IPR019793. Peroxidases_heam-ligand_BS. [Graphical view] |
| Pfam | PF00141. peroxidase. 1 hit. [Graphical view] |
| PRINTS | PR00458. PEROXIDASE. PR00461. PLPEROXIDASE. |
| PROSITE | PS00435. PEROXIDASE_1. 1 hit. PS00436. PEROXIDASE_2. 1 hit. PS50873. PEROXIDASE_4. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | PER47_ARATH | ||||||||
| Accession | Primary (citable) accession number: Q9SZB9 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | PPAP (Plant Proteome Annotation Project) | ||||||||
Relevant documents
| Arabidopsis thaliana Arabidopsis thaliana: entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with


