Q9SZB9 (PER47_ARATH) Reviewed, UniProtKB/Swiss-Prot
Last modified
December 14, 2011.
Version 85.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Peroxidase 47 Short name=Atperox P47 EC=1.11.1.7 Alternative name(s): ATP32 | ||||||||
| Gene names |
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| Organism | Arabidopsis thaliana (Mouse-ear cress) | ||||||||
| Taxonomic identifier | 3702 [NCBI] | ||||||||
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Protein attributes
| Sequence length | 325 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Function | Removal of H2O2, oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue. |
| Catalytic activity | 2 phenolic donor + H2O2 = 2 phenoxyl radical of the donor + 2 H2O. |
| Cofactor | Binds 1 heme B (iron-protoporphyrin IX) group per subunit By similarity. Binds 2 calcium ions per subunit By similarity. |
| Subcellular location | Secreted By similarity. |
| Developmental stage | Up-regulated during leaf development. Ref.5 |
| Miscellaneous | There are 73 peroxidase genes in A.thaliana. |
| Sequence similarities | Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily. |
| Sequence caution | The sequence AAL40837.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended. The sequence CAB38800.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended. The sequence CAB80059.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Secreted |
| Domain | Signal |
| Ligand | Calcium Heme Iron Metal-binding |
| Molecular function | Oxidoreductase Peroxidase |
| PTM | Disulfide bond Glycoprotein |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | response to oxidative stress Inferred from electronic annotation. Source: InterPro |
| Cellular component | extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | heme binding Inferred from electronic annotation. Source: InterPro peroxidase activityInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||||
Molecule processing | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal peptide | 1 – 36 | 36 | Potential | ||||||||
| Chain | 37 – 325 | 289 | Peroxidase 47 | PRO_0000023713 | |||||||
Sites | |||||||||||
| Active site | 77 | 1 | Proton acceptor By similarity | ||||||||
| Metal binding | 78 | 1 | Calcium 1 By similarity | ||||||||
| Metal binding | 83 | 1 | Calcium 1; via carbonyl oxygen By similarity | ||||||||
| Metal binding | 85 | 1 | Calcium 1 By similarity | ||||||||
| Metal binding | 87 | 1 | Calcium 1 By similarity | ||||||||
| Metal binding | 202 | 1 | Iron (heme axial ligand) By similarity | ||||||||
| Metal binding | 203 | 1 | Calcium 2 By similarity | ||||||||
| Metal binding | 246 | 1 | Calcium 2 By similarity | ||||||||
| Metal binding | 248 | 1 | Calcium 2 By similarity | ||||||||
| Metal binding | 253 | 1 | Calcium 2 By similarity | ||||||||
| Binding site | 172 | 1 | Substrate; via carbonyl oxygen By similarity | ||||||||
| Site | 73 | 1 | Transition state stabilizer By similarity | ||||||||
Amino acid modifications | |||||||||||
| Glycosylation | 177 | 1 | N-linked (GlcNAc...) Potential | ||||||||
| Disulfide bond | 46 ↔ 125 | By similarity | |||||||||
| Disulfide bond | 79 ↔ 84 | By similarity | |||||||||
| Disulfide bond | 131 ↔ 321 | By similarity | |||||||||
| Disulfide bond | 209 ↔ 235 | By similarity | |||||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Structural diversity and transcription of class III peroxidases from Arabidopsis thaliana." Welinder K.G., Justesen A.F., Kjaersgaard I.V.H., Jensen R.B., Rasmussen S.K., Jespersen H.M., Duroux L. Eur. J. Biochem. 269:6063-6081(2002) [PubMed: 12473102] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Columbia. |
| [2] | "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana." Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B. McCombie W.R.Nature 402:769-777(1999) [PubMed: 10617198] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia. |
| [3] | The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia. |
| [4] | "Arabidopsis ORF clones." De Los Reyes C., Quan R., Chen H., Bautista V.R., Kim C.J., Ecker J.R. Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia. |
| [5] | "Toward elucidating the global gene expression patterns of developing Arabidopsis: parallel analysis of 8300 genes by a high-density oligonucleotide probe array." Zhu T., Budworth P., Han B., Brown D., Chang H.-S., Zou G., Wang X. Plant Physiol. Biochem. 39:221-242(2001) Cited for: DEVELOPMENTAL STAGE. Strain: cv. Columbia. |
| [6] | "Analysis and expression of the class III peroxidase large gene family in Arabidopsis thaliana." Tognolli M., Penel C., Greppin H., Simon P. Gene 288:129-138(2002) [PubMed: 12034502] [Abstract] Cited for: GENE FAMILY ORGANIZATION, NOMENCLATURE. Strain: cv. Columbia. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AF451951 mRNA. Translation: AAL40837.1. Different initiation. AL035678 Genomic DNA. Translation: CAB38800.1. Different initiation. AL161583 Genomic DNA. Translation: CAB80059.1. Different initiation. CP002687 Genomic DNA. Translation: AEE86222.1. BT044614 mRNA. Translation: ACI31314.1. |
| IPI | IPI00539387. |
| PIR | T05993. |
| RefSeq | NP_567919.1. NM_119496.3. |
| UniGene | At.28650. |
3D structure databases | |
| ProteinModelPortal | Q9SZB9. |
| SMR | Q9SZB9. Positions 43-315. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q9SZB9. |
Protein family/group databases | |
| PeroxiBase | 213. AtPrx47. |
Proteomic databases | |
| PRIDE | Q9SZB9. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblPlants | AT4G33420.1; AT4G33420.1; AT4G33420. |
| GeneID | 829479. |
| GenomeReviews | Gene locus AT4G33420 in contig CT486007_GR. |
| KEGG | ath:AT4G33420. |
| NMPDR | fig|3702.1.peg.21384. |
Organism-specific databases | |
| GeneFarm | 1879. 61. |
| TAIR | At4g33420. |
Phylogenomic databases | |
| GeneTree | EPGT00050000003124. |
| HOGENOM | HBG597790. |
| InParanoid | Q9SZB9. |
Gene expression databases | |
| Genevestigator | Q9SZB9. |
| GermOnline | AT4G33420. Arabidopsis thaliana. |
Family and domain databases | |
| InterPro | IPR010255. Haem_peroxidase. IPR002016. Haem_peroxidase_pln/fun/bac. IPR000823. Peroxidase_pln. IPR019794. Peroxidases_AS. IPR019793. Peroxidases_heam-ligand_BS. [Graphical view] |
| KO | K00430. |
| Pfam | PF00141. peroxidase. 1 hit. [Graphical view] |
| PRINTS | PR00458. PEROXIDASE. PR00461. PLPEROXIDASE. |
| SUPFAM | SSF48113. Peroxidase_super. 1 hit. |
| PROSITE | PS00435. PEROXIDASE_1. 1 hit. PS00436. PEROXIDASE_2. 1 hit. PS50873. PEROXIDASE_4. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | PER47_ARATH | ||||||||
| Accession | Primary (citable) accession number: Q9SZB9 Secondary accession number(s): B5X0P5 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Plant Protein Annotation Program | ||||||||
Relevant documents
| Arabidopsis thaliana Arabidopsis thaliana: entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with