SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9SZ92

- CK3_ARATH

UniProt

Q9SZ92 - CK3_ARATH

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Probable choline kinase 3
Gene
At4g09760, F17A8.110
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Involved in phospholipid biosynthesis. Catalyzes the first step in phosphatidylcholine biosynthesis By similarity.

Catalytic activityi

ATP + choline = ADP + phosphocholine.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei71 – 711ATP By similarity
Binding sitei207 – 2071ATP By similarity
Binding sitei224 – 2241ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. choline kinase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT4G09760-MONOMER.
ARA:GQT-1965-MONOMER.
UniPathwayiUPA00753; UER00737.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable choline kinase 3 (EC:2.7.1.32)
Gene namesi
Ordered Locus Names:At4g09760
ORF Names:F17A8.110
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 4

Organism-specific databases

TAIRiAT4G09760.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 346346Probable choline kinase 3
PRO_0000423348Add
BLAST

Proteomic databases

PRIDEiQ9SZ92.

Expressioni

Inductioni

By wounding, and salt and osmotic stresses.1 Publication

Gene expression databases

ArrayExpressiQ9SZ92.
GenevestigatoriQ9SZ92.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT4G09760.1-P.

Structurei

3D structure databases

ProteinModelPortaliQ9SZ92.
SMRiQ9SZ92. Positions 36-342.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

InParanoidiQ9SZ92.
KOiK14156.
OMAiVSHESID.
PhylomeDBiQ9SZ92.

Family and domain databases

InterProiIPR026712. Cho/Etha_kinase.
IPR011009. Kinase-like_dom.
[Graphical view]
PANTHERiPTHR22603:SF32. PTHR22603:SF32. 1 hit.
SUPFAMiSSF56112. SSF56112. 1 hit.

Sequencei

Sequence statusi: Complete.

This entry describes 1 isoform i produced by alternative splicing. Align

Note: A number of isoforms are produced. According to EST sequences.

Isoform 1 (identifier: Q9SZ92-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MAVGIFGLIP SSSPDELRKI LQALSTKWGD VVEDFESLEV KPMKGAMTNE    50
VFMVSWPRKE TNLRCRKLLV RVYGEGVELF FNRDDEIRTF EYVARHGHGP 100
TLLGRFAGGR VEEFIHARTL SATDLRDPNI SALVASKLRR FHSIHIPGDR 150
IMLIWDRMRT WVGQAKNLCS NEHSTEFGLD DIEDEINLLE QEVNNEQEIG 200
FCHNDLQYGN IMIDEETNAI TIIDYEYASY NPIAYDIANH FCEMAADYHS 250
NTPHILDYTL YPGEEERRRF ICNYLTSSGE EAREEDIEQL LDDIEKYTLA 300
SHLFWGLWGI ISGYVNKIEF DYIEYSRQRF KQYWLRKPKL LSFFPS 346
Length:346
Mass (Da):40,351
Last modified:May 1, 2000 - v1
Checksum:iCF5CCA7CF80F5FF7
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti64 – 674RCRK → QCRN in AAM66047. 1 Publication
Sequence conflicti151 – 1511I → T in AAM61617. 1 Publication
Sequence conflicti175 – 1751T → S in AAM61617. 1 Publication
Sequence conflicti181 – 1833DIE → CID in AAM61617. 1 Publication
Sequence conflicti219 – 2191A → T in AAM66047. 1 Publication
Sequence conflicti288 – 2881E → D in AAM61617. 1 Publication
Sequence conflicti344 – 3441F → Y in AAM61617. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL049482 Genomic DNA. Translation: CAB39643.1.
AL161515 Genomic DNA. Translation: CAB78099.1.
CP002687 Genomic DNA. Translation: AEE82792.1.
CP002687 Genomic DNA. Translation: AEE82793.1.
AY085061 mRNA. Translation: AAM61617.1.
AY088512 mRNA. Translation: AAM66047.1.
PIRiT04023.
RefSeqiNP_192714.1. NM_117044.3. [Q9SZ92-1]
NP_849350.1. NM_179019.1. [Q9SZ92-1]
UniGeneiAt.27989.
At.33676.

Genome annotation databases

EnsemblPlantsiAT4G09760.1; AT4G09760.1; AT4G09760. [Q9SZ92-1]
AT4G09760.2; AT4G09760.2; AT4G09760. [Q9SZ92-1]
GeneIDi826564.
KEGGiath:AT4G09760.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL049482 Genomic DNA. Translation: CAB39643.1 .
AL161515 Genomic DNA. Translation: CAB78099.1 .
CP002687 Genomic DNA. Translation: AEE82792.1 .
CP002687 Genomic DNA. Translation: AEE82793.1 .
AY085061 mRNA. Translation: AAM61617.1 .
AY088512 mRNA. Translation: AAM66047.1 .
PIRi T04023.
RefSeqi NP_192714.1. NM_117044.3. [Q9SZ92-1 ]
NP_849350.1. NM_179019.1. [Q9SZ92-1 ]
UniGenei At.27989.
At.33676.

3D structure databases

ProteinModelPortali Q9SZ92.
SMRi Q9SZ92. Positions 36-342.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 3702.AT4G09760.1-P.

Proteomic databases

PRIDEi Q9SZ92.

Protocols and materials databases

DNASUi 826564.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT4G09760.1 ; AT4G09760.1 ; AT4G09760 . [Q9SZ92-1 ]
AT4G09760.2 ; AT4G09760.2 ; AT4G09760 . [Q9SZ92-1 ]
GeneIDi 826564.
KEGGi ath:AT4G09760.

Organism-specific databases

TAIRi AT4G09760.

Phylogenomic databases

InParanoidi Q9SZ92.
KOi K14156.
OMAi VSHESID.
PhylomeDBi Q9SZ92.

Enzyme and pathway databases

UniPathwayi UPA00753 ; UER00737 .
BioCyci ARA:AT4G09760-MONOMER.
ARA:GQT-1965-MONOMER.

Gene expression databases

ArrayExpressi Q9SZ92.
Genevestigatori Q9SZ92.

Family and domain databases

InterProi IPR026712. Cho/Etha_kinase.
IPR011009. Kinase-like_dom.
[Graphical view ]
PANTHERi PTHR22603:SF32. PTHR22603:SF32. 1 hit.
SUPFAMi SSF56112. SSF56112. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana."
    Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B.
    , Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.
    Nature 402:769-777(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Full-length cDNA from Arabidopsis thaliana."
    Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
    Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  4. "Regulation of phosphatidylcholine biosynthesis under salt stress involves choline kinases in Arabidopsis thaliana."
    Tasseva G., Richard L., Zachowski A.
    FEBS Lett. 566:115-120(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION.

Entry informationi

Entry nameiCK3_ARATH
AccessioniPrimary (citable) accession number: Q9SZ92
Secondary accession number(s): Q8L9C6, Q8LF42
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 18, 2013
Last sequence update: May 1, 2000
Last modified: June 11, 2014
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi