Q9SZ83 (Y4967_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized oxidoreductase At4g09670
EC=1.-.-.-

Gene names

Ordered Locus Names:	At4g09670
ORF Names:	F17A8.20

Organism

Arabidopsis thaliana (Mouse-ear cress)

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	362 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subunit structure	Homodimer Potential. Ref.6
Sequence similarities	Belongs to the gfo/idh/mocA family.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	cytosol Inferred from direct assay. Source: TAIR
Molecular function	nucleotide binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 362

362

Uncharacterized oxidoreductase At4g09670

PRO_0000091788

Experimental info

Sequence conflict

173

1

I → M in BAD94240. Ref.5

Secondary structure

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362

Helix Strand Turn

Details...

Beta strand

7 – 13

7

Helix

18 – 27

10

Beta strand

31 – 37

7

Helix

41 – 50

10

Beta strand

58 – 62

5

Helix

63 – 68

6

Beta strand

74 – 77

4

Helix

81 – 83

3

Helix

84 – 92

9

Turn

93 – 95

3

Beta strand

97 – 100

4

Beta strand

105 – 107

3

Helix

108 – 119

12

Turn

120 – 122

3

Beta strand

125 – 127

3

Helix

131 – 133

3

Helix

135 – 137

3

Turn

138 – 142

5

Helix

143 – 145

3

Turn

147 – 150

4

Beta strand

152 – 163

12

Helix

166 – 171

6

Helix

173 – 175

3

Helix

183 – 187

5

Helix

189 – 199

11

Turn

200 – 202

3

Beta strand

206 – 210

5

Beta strand

222 – 230

9

Beta strand

232 – 234

3

Beta strand

236 – 264

29

Beta strand

273 – 281

9

Beta strand

288 – 293

6

Beta strand

296 – 301

6

Helix

306 – 314

9

Helix

332 – 351

20

Turn

352 – 354

3

Sequences

	Sequence		Length	Mass (Da)
	Q9SZ83 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: EC2595BE6C53AACC	FASTA	362	39,562
	10 20 30 40 50 60 MATETQIRIG VMGCADIARK VSRAIHLAPN ATISGVASRS LEKAKAFATA NNYPESTKIH 70 80 90 100 110 120 GSYESLLEDP EIDALYVPLP TSLHVEWAIK AAEKGKHILL EKPVAMNVTE FDKIVDACEA 130 140 150 160 170 180 NGVQIMDGTM WVHNPRTALL KEFLSDSERF GQLKTVQSCF SFAGDEDFLK NDIRVKPGLD 190 200 210 220 230 240 GLGALGDAGW YAIRATLLAN NFELPKTVTA FPGAVLNEAG VILSCGASLS WEDGRTATIY 250 260 270 280 290 300 CSFLANLTME ITAIGTKGTL RVHDFIIPYK ETEASFTTST KAWFNDLVTA WVSPPSEHTV 310 320 330 340 350 360 KTELPQEACM VREFARLVGE IKNNGAKPDG YWPSISRKTQ LVVDAVKESV DKNYQQISLS GR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana." Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B. , Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R. Nature 402:769-777(1999) [PubMed: 10617198] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	"Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R. Science 302:842-846(2003) [PubMed: 14593172] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[4]	"Full-length cDNA from Arabidopsis thaliana." Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[5]	"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs." Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K. , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K. Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 173-362. Strain: cv. Columbia.
[6]	"X-ray structure of gene product from Arabidopsis thaliana At4g09670." Center for eukaryotic structural genomics (CESG) Submitted (JAN-2005) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.49 ANGSTROMS) OF 2-362, SUBUNIT.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AL049482 Genomic DNA. Translation: CAB39634.1.
AL161515 Genomic DNA. Translation: CAB78090.1.
CP002687 Genomic DNA. Translation: AEE82779.1.
BT002355 mRNA. Translation: AAN86188.1.
AY045851 mRNA. Translation: AAK76525.2.
AY085911 mRNA. Translation: AAM63123.1.
AK220867 mRNA. Translation: BAD94240.1.

IPI

IPI00536577.

PIR

T04014.

RefSeq

NP_192705.1. NM_117035.3.

UniGene

At.23812.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1YDW	X-ray	2.49	A/B	2-362	[»]
2Q4E	X-ray	2.49	A/B	2-362	[»]

ProteinModelPortal

Q9SZ83.

SMR

Q9SZ83. Positions 6-360.

ModBase

Search...

Protein-protein interaction databases

STRING

Q9SZ83.

Proteomic databases

PRIDE

Q9SZ83.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblPlants

AT4G09670.1; AT4G09670.1; AT4G09670.

GeneID

826553.

GenomeReviews

Gene locus AT4G09670 in contig CT486007_GR.

KEGG

ath:AT4G09670.

NMPDR

fig|3702.1.peg.18618.

Organism-specific databases

TAIR

At4g09670.

Phylogenomic databases

eggNOG

KOG2741.

GeneTree

EPGT00050000010923.

HOGENOM

HBG318909.

InParanoid

Q9SZ83.

OMA

GAANIAW.

PhylomeDB

Q9SZ83.

ProtClustDB

CLSN2679712.

Gene expression databases

Genevestigator

Q9SZ83.

GermOnline

AT4G09670. Arabidopsis thaliana.

Family and domain databases

InterPro

IPR016040. NAD(P)-bd_dom.
IPR000683. Oxidoreductase_N.
IPR004104. OxRdtase_C.
[Graphical view]

Gene3D

G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.

Pfam

PF01408. GFO_IDH_MocA. 1 hit.
PF02894. GFO_IDH_MocA_C. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Y4967_ARATH

Accession

Primary (citable) accession number: Q9SZ83
Secondary accession number(s): Q56ZU4, Q94AR5

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 30, 2005
Last sequence update:	May 1, 2000
Last modified:	December 14, 2011
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program