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Protein

Nuclear transcription factor Y subunit A-5

Gene

NFYA5

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters (By similarity). Involved in the blue light (BL) and abscisic acid (ABA) signaling pathways.By similarity1 Publication

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi211 – 23626NFYA/HAP2-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  • DNA binding Source: UniProtKB-KW
  • transcription factor activity, sequence-specific DNA binding Source: TAIR

GO - Biological processi

  • abscisic acid-activated signaling pathway Source: UniProtKB
  • blue light signaling pathway Source: UniProtKB
  • embryo development ending in seed dormancy Source: TAIR
  • negative regulation of transcription, DNA-templated Source: TAIR
  • response to water deprivation Source: TAIR
  • seed development Source: TAIR
  • somatic embryogenesis Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Abscisic acid signaling pathway, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

ReactomeiR-ATH-2426168. Activation of gene expression by SREBF (SREBP).

Names & Taxonomyi

Protein namesi
Recommended name:
Nuclear transcription factor Y subunit A-5
Short name:
AtNF-YA-5
Gene namesi
Name:NFYA5
Ordered Locus Names:At1g54160
ORF Names:F15I1.26
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G54160.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Disruption phenotypei

Altered response to blue light (BL) and abscisic acid (ABA).1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 308308Nuclear transcription factor Y subunit A-5PRO_0000198775Add
BLAST

Proteomic databases

PaxDbiQ9SYH4.
PRIDEiQ9SYH4.

Expressioni

Tissue specificityi

Expressed in the whole plant, except roots. Present in etiolated seedlings.2 Publications

Gene expression databases

GenevisibleiQ9SYH4. AT.

Interactioni

Subunit structurei

Heterotrimeric transcription factor composed of three components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and dimerize for NF-YA association and DNA binding (By similarity).By similarity

Protein-protein interaction databases

BioGridi27081. 3 interactions.
STRINGi3702.AT1G54160.1.

Structurei

3D structure databases

ProteinModelPortaliQ9SYH4.
SMRiQ9SYH4. Positions 179-234.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi181 – 20424Subunit association domain (SAD)Add
BLAST

Sequence similaritiesi

Belongs to the NFYA/HAP2 subunit family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1561. Eukaryota.
COG5224. LUCA.
HOGENOMiHOG000239782.
InParanoidiQ9SYH4.
KOiK08064.
OMAiYPSTHHA.
OrthoDBiEOG09360H5Y.
PhylomeDBiQ9SYH4.

Family and domain databases

InterProiIPR018362. CCAAT-binding_factor_CS.
IPR001289. NFYA.
[Graphical view]
PANTHERiPTHR12632. PTHR12632. 1 hit.
PfamiPF02045. CBFB_NFYA. 1 hit.
[Graphical view]
PRINTSiPR00616. CCAATSUBUNTB.
SMARTiSM00521. CBF. 1 hit.
[Graphical view]
PROSITEiPS00686. NFYA_HAP2_1. 1 hit.
PS51152. NFYA_HAP2_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9SYH4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQVFQRKEDS SWGNSMPTTN SNIQGSESFS LTKDMIMSTT QLPAMKHSGL
60 70 80 90 100
QLQNQDSTSS QSTEEESGGG EVASFGEYKR YGCSIVNNNL SGYIENLGKP
110 120 130 140 150
IENYTKSITT SSMVSQDSVF PAPTSGQISW SLQCAETSHF NGFLAPEYAS
160 170 180 190 200
TPTALPHLEM MGLVSSRVPL PHHIQENEPI FVNAKQYHAI LRRRKHRAKL
210 220 230 240 250
EAQNKLIKCR KPYLHESRHL HALKRARGSG GRFLNTKKLQ ESSNSLCSSQ
260 270 280 290 300
MANGQNFSMS PHGGGSGIGS SSISPSSNSN CINMFQNPQF RFSGYPSTHH

ASALMSGT
Length:308
Mass (Da):33,774
Last modified:May 1, 2000 - v1
Checksum:iECD29EEA85FB6860
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006577 Genomic DNA. Translation: AAD25790.1.
CP002684 Genomic DNA. Translation: AEE33056.1.
AF386957 mRNA. Translation: AAK62402.1.
AY081445 mRNA. Translation: AAM10007.1.
PIRiG96582.
RefSeqiNP_175818.1. NM_104294.3.
UniGeneiAt.48305.
At.57160.

Genome annotation databases

EnsemblPlantsiAT1G54160.1; AT1G54160.1; AT1G54160.
GeneIDi841856.
GrameneiAT1G54160.1; AT1G54160.1; AT1G54160.
KEGGiath:AT1G54160.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006577 Genomic DNA. Translation: AAD25790.1.
CP002684 Genomic DNA. Translation: AEE33056.1.
AF386957 mRNA. Translation: AAK62402.1.
AY081445 mRNA. Translation: AAM10007.1.
PIRiG96582.
RefSeqiNP_175818.1. NM_104294.3.
UniGeneiAt.48305.
At.57160.

3D structure databases

ProteinModelPortaliQ9SYH4.
SMRiQ9SYH4. Positions 179-234.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi27081. 3 interactions.
STRINGi3702.AT1G54160.1.

Proteomic databases

PaxDbiQ9SYH4.
PRIDEiQ9SYH4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G54160.1; AT1G54160.1; AT1G54160.
GeneIDi841856.
GrameneiAT1G54160.1; AT1G54160.1; AT1G54160.
KEGGiath:AT1G54160.

Organism-specific databases

TAIRiAT1G54160.

Phylogenomic databases

eggNOGiKOG1561. Eukaryota.
COG5224. LUCA.
HOGENOMiHOG000239782.
InParanoidiQ9SYH4.
KOiK08064.
OMAiYPSTHHA.
OrthoDBiEOG09360H5Y.
PhylomeDBiQ9SYH4.

Enzyme and pathway databases

ReactomeiR-ATH-2426168. Activation of gene expression by SREBF (SREBP).

Miscellaneous databases

PROiQ9SYH4.

Gene expression databases

GenevisibleiQ9SYH4. AT.

Family and domain databases

InterProiIPR018362. CCAAT-binding_factor_CS.
IPR001289. NFYA.
[Graphical view]
PANTHERiPTHR12632. PTHR12632. 1 hit.
PfamiPF02045. CBFB_NFYA. 1 hit.
[Graphical view]
PRINTSiPR00616. CCAATSUBUNTB.
SMARTiSM00521. CBF. 1 hit.
[Graphical view]
PROSITEiPS00686. NFYA_HAP2_1. 1 hit.
PS51152. NFYA_HAP2_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNFYA5_ARATH
AccessioniPrimary (citable) accession number: Q9SYH4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: May 1, 2000
Last modified: September 7, 2016
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.