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Q9SXP2

- FDH1_ORYSJ

UniProt

Q9SXP2 - FDH1_ORYSJ

Protein

Formate dehydrogenase 1, mitochondrial

Gene

Os06g0486800

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 82 (01 Oct 2014)
      Sequence version 2 (07 Mar 2006)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Formate + NAD+ = CO2 + NADH.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei253 – 2531NAD; via carbonyl oxygenBy similarity
    Active sitei282 – 2821By similarity
    Binding sitei306 – 3061NADBy similarity
    Active sitei330 – 3301Proton donorBy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi199 – 2002NADBy similarity
    Nucleotide bindingi280 – 2823NADBy similarity
    Nucleotide bindingi330 – 3334NADBy similarity

    GO - Molecular functioni

    1. formate dehydrogenase (NAD+) activity Source: UniProtKB-EC
    2. NAD binding Source: InterPro
    3. oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    NAD

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Formate dehydrogenase 1, mitochondrial (EC:1.2.1.2)
    Alternative name(s):
    NAD-dependent formate dehydrogenase 1
    Short name:
    FDH 1
    Gene namesi
    Ordered Locus Names:Os06g0486800, LOC_Os06g29180
    ORF Names:P0008F02.23, P0404G03.8
    OrganismiOryza sativa subsp. japonica (Rice)
    Taxonomic identifieri39947 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
    ProteomesiUP000000763: Chromosome 6

    Organism-specific databases

    GrameneiQ9SXP2.

    Subcellular locationi

    Mitochondrion By similarity

    GO - Cellular componenti

    1. mitochondrion Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Mitochondrion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transit peptidei1 – 2020Mitochondrion1 PublicationAdd
    BLAST
    Chaini21 – 376356Formate dehydrogenase 1, mitochondrialPRO_0000007195Add
    BLAST

    Proteomic databases

    PaxDbiQ9SXP2.
    PRIDEiQ9SXP2.

    Interactioni

    Protein-protein interaction databases

    STRINGi39947.LOC_Os06g29180.1.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9SXP2.
    SMRiQ9SXP2. Positions 42-372.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transit peptide

    Phylogenomic databases

    eggNOGiCOG1052.
    HOGENOMiHOG000136703.
    KOiK00122.
    OMAiGCRRVEN.

    Family and domain databases

    Gene3Di3.40.50.720. 2 hits.
    InterProiIPR006139. D-isomer_2_OHA_DH_cat_dom.
    IPR006140. D-isomer_DH_NAD-bd.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PfamiPF00389. 2-Hacid_dh. 1 hit.
    PF02826. 2-Hacid_dh_C. 1 hit.
    [Graphical view]
    PROSITEiPS00065. D_2_HYDROXYACID_DH_1. 1 hit.
    PS00670. D_2_HYDROXYACID_DH_2. 1 hit.
    PS00671. D_2_HYDROXYACID_DH_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q9SXP2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAMWRAAAGH LLGRALGSRA AHTSAGSKKI VGVFYKGGEY ADKNPNFVGC    50
    VEGALGIREW LESKGHHYIV TDDKEGLNSE LEKHIEDMHV LITTPFHPAY 100
    VSAERIKKAK NLELLLTAGI GSDHIDLPAA AAAGLTVAEV TGSNTVSVAE 150
    DELMRILILL RNFLPGYQQV VHGEWNVAGI AYRAYDLEGK TVGTVGAGRI 200
    GRLLLQRLKP FNCNLLYHDR LKIDPELEKE IGAKYEEDLD AMLPKCDVIV 250
    INTPLTEKTR GMFNKERIAK MKKGVIIVNN ARGAIMDTQA VADACSSGQV 300
    AGYGGDVWFP QPAPKDHPWR YMPNHAMTPH ISGTTIDAQL RYAAGVKDML 350
    DRYFKGEDFP VQNYIVKEGQ LASQYQ 376
    Length:376
    Mass (Da):41,341
    Last modified:March 7, 2006 - v2
    Checksum:i9FE964AE572C585B
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti316 – 3172DH → GP in BAA77337. 1 PublicationCurated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB019533 mRNA. Translation: BAA77337.1.
    AP003518 Genomic DNA. Translation: BAD37348.1.
    AP005656 Genomic DNA. Translation: BAD38299.1.
    RefSeqiNP_001057666.1. NM_001064201.1.
    UniGeneiOs.4156.

    Genome annotation databases

    EnsemblPlantsiOS06T0486800-01; OS06T0486800-01; OS06G0486800.
    GeneIDi4341069.
    KEGGiosa:4341069.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB019533 mRNA. Translation: BAA77337.1 .
    AP003518 Genomic DNA. Translation: BAD37348.1 .
    AP005656 Genomic DNA. Translation: BAD38299.1 .
    RefSeqi NP_001057666.1. NM_001064201.1.
    UniGenei Os.4156.

    3D structure databases

    ProteinModelPortali Q9SXP2.
    SMRi Q9SXP2. Positions 42-372.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 39947.LOC_Os06g29180.1.

    Proteomic databases

    PaxDbi Q9SXP2.
    PRIDEi Q9SXP2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi OS06T0486800-01 ; OS06T0486800-01 ; OS06G0486800 .
    GeneIDi 4341069.
    KEGGi osa:4341069.

    Organism-specific databases

    Gramenei Q9SXP2.

    Phylogenomic databases

    eggNOGi COG1052.
    HOGENOMi HOG000136703.
    KOi K00122.
    OMAi GCRRVEN.

    Family and domain databases

    Gene3Di 3.40.50.720. 2 hits.
    InterProi IPR006139. D-isomer_2_OHA_DH_cat_dom.
    IPR006140. D-isomer_DH_NAD-bd.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    Pfami PF00389. 2-Hacid_dh. 1 hit.
    PF02826. 2-Hacid_dh_C. 1 hit.
    [Graphical view ]
    PROSITEi PS00065. D_2_HYDROXYACID_DH_1. 1 hit.
    PS00670. D_2_HYDROXYACID_DH_2. 1 hit.
    PS00671. D_2_HYDROXYACID_DH_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "NAD-dependent formate dehydrogenase."
      Shiraishi T., Fukusaki E., Kobayashi A.
      Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    3. "Rice proteome database based on two-dimensional polyacrylamide gel electrophoresis: its status in 2003."
      Komatsu S., Kojima K., Suzuki K., Ozaki K., Higo K.
      Nucleic Acids Res. 32:D388-D392(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 21-30.
      Strain: cv. Nipponbare.
      Tissue: Callus.

    Entry informationi

    Entry nameiFDH1_ORYSJ
    AccessioniPrimary (citable) accession number: Q9SXP2
    Secondary accession number(s): Q67U72
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 27, 2002
    Last sequence update: March 7, 2006
    Last modified: October 1, 2014
    This is version 82 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3