Q9SXB0 (SY125_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Syntaxin-125
Short name=AtSYP125

Gene names

Name:	SYP125
Ordered Locus Names:	At1g11250
ORF Names:	T28P6.10

Organism

Arabidopsis thaliana (Mouse-ear cress) [Reference proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	298 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Vesicle trafficking protein that functions in the secretory pathway By similarity.
Subunit structure	Part of the t-SNARE complex By similarity.
Subcellular location	Membrane; Single-pass type IV membrane protein By similarity.
Sequence similarities	Belongs to the syntaxin family. Contains 1 t-SNARE coiled-coil homology domain.

Ontologies

Keywords
Biological process	Protein transport Transport
Cellular component	Membrane
Domain	Coiled coil Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	intracellular protein transport Inferred from electronic annotation. Source: InterPro vesicle-mediated transport Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 298	298	Syntaxin-125		PRO_0000210250
Regions
	Topological domain	1 – 274	274	Cytoplasmic Potential
	Transmembrane	275 – 295	21	Helical; Anchor for type IV membrane protein; Potential
	Topological domain	296 – 298	3	Vesicular Potential
	Domain	198 – 260	63	t-SNARE coiled-coil homology
	Coiled coil	25 – 155	131	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q9SXB0 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 6BECC870842205B8	FASTA	298	33,826
	10 20 30 40 50 60 MNDLFSNSFK KNQAQLGDVE AGQETMNLDK FFEDVENVKD DMKGVEALYK KLQDSNEECK 70 80 90 100 110 120 TVHNAKKVKE LRAKMDGDVA MVLKRVKIIK QKLEALEKAN ANSRNVPGCG PGSSTDRTRS 130 140 150 160 170 180 SVVSGLGKKL KDLMDSFQGL RARMNNEYKE TVERRYFTIT GEKADEQTID NLIASGESEN 190 200 210 220 230 240 FLQKAIQEQG RGQILDTISE IQERHDAVKE IEKNLLELHQ VFLDMAALVE AQGQQLNNIE 250 260 270 280 290 SHVAKASSFV RRGTDQLQDA REYQKSSRKW TCYAIILFIV IFILLLIPLL PHIMLMLK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W. Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W., Redman J.C., Wu H.C., Utterback T., Town C.D. Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC007259 Genomic DNA. Translation: AAD50004.1. CP002684 Genomic DNA. Translation: AEE28704.1. DQ056451 mRNA. Translation: AAY78608.1.
IPI	IPI00519644.
PIR	D86246.
RefSeq	NP_172591.1. NM_100997.1.
UniGene	At.51565.
3D structure databases
ProteinModelPortal	Q9SXB0.
SMR	Q9SXB0. Positions 28-285.
ModBase	Search...
Proteomic databases
PaxDb	Q9SXB0.
PRIDE	Q9SXB0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT1G11250.1; AT1G11250.1; AT1G11250.
GeneID	837666.
KEGG	ath:AT1G11250.
Organism-specific databases
GeneFarm	2181. 383.
TAIR	At1g11250.
Phylogenomic databases
eggNOG	NOG236854.
HOGENOM	HOG000238904.
InParanoid	Q9SXB0.
KO	K08486.
OMA	IMIMICC.
PhylomeDB	Q9SXB0.
ProtClustDB	CLSN2681842.
Gene expression databases
Genevestigator	Q9SXB0.
GermOnline	AT1G11250. Arabidopsis thaliana.
Family and domain databases
InterPro	IPR006012. Syntaxin/epimorphin_CS. IPR006011. Syntaxin_N. IPR010989. t-SNARE. IPR000727. T_SNARE_dom. [Graphical view]
Pfam	PF05739. SNARE. 1 hit. PF00804. Syntaxin. 1 hit. [Graphical view]
SMART	SM00503. SynN. 1 hit. SM00397. t_SNARE. 1 hit. [Graphical view]
SUPFAM	SSF47661. t-snare. 1 hit.
PROSITE	PS00914. SYNTAXIN. 1 hit. PS50192. T_SNARE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SY125_ARATH

Accession

Primary (citable) accession number: Q9SXB0
Secondary accession number(s): Q4PT35

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 12, 2003
Last sequence update:	May 1, 2000
Last modified:	May 1, 2013
This is version 82 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program