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Protein

Phytochrome-associated serine/threonine-protein phosphatase 1

Gene

FYPP1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Dephosphorylates phosphorylated phytochromes, with a preference toward Pfr forms. Plays a major role in the photoperiodic control of flowering time in long days by modulating phytochrome signals in flowering time control (By similarity).By similarity1 Publication

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mn2+By similarityNote: Binds 2 manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi50Manganese 1By similarity1
Metal bindingi52Manganese 1By similarity1
Metal bindingi78Manganese 1By similarity1
Metal bindingi78Manganese 2By similarity1
Metal bindingi110Manganese 2By similarity1
Active sitei111Proton donorBy similarity1
Metal bindingi160Manganese 2By similarity1
Metal bindingi234Manganese 2By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandManganese, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Phytochrome-associated serine/threonine-protein phosphatase 1 (EC:3.1.3.16)
Short name:
AtFyPP1
Gene namesi
Name:FYPP1
Ordered Locus Names:At1g50370
ORF Names:F14I3.5
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G50370
TAIRilocus:2011907 AT1G50370

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003089891 – 303Phytochrome-associated serine/threonine-protein phosphatase 1Add BLAST303

Proteomic databases

PaxDbiQ9SX52
PRIDEiQ9SX52

Expressioni

Tissue specificityi

Mostly expressed in flowers. Also detected to a lower extent in stems and leaves.1 Publication

Gene expression databases

ExpressionAtlasiQ9SX52 baseline and differential
GenevisibleiQ9SX52 AT

Interactioni

Subunit structurei

Interacts with PHYA and PHYB, mostly when they are phosphorylated and in Pfr forms (By similarity). Interacts with TAP46 (PubMed:21216945, PubMed:24357600).By similarity2 Publications

Protein-protein interaction databases

BioGridi26684, 11 interactors
IntActiQ9SX52, 1 interactor
STRINGi3702.AT1G50370.1

Structurei

3D structure databases

ProteinModelPortaliQ9SX52
SMRiQ9SX52
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0373 Eukaryota
ENOG410XNR9 LUCA
HOGENOMiHOG000172696
InParanoidiQ9SX52
KOiK15498
OMAiKYCCRVF
OrthoDBiEOG09360F5Z
PhylomeDBiQ9SX52

Family and domain databases

Gene3Di3.60.21.10, 1 hit
InterProiView protein in InterPro
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
IPR006186 Ser/Thr-sp_prot-phosphatase
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PRINTSiPR00114 STPHPHTASE
SMARTiView protein in SMART
SM00156 PP2Ac, 1 hit
PROSITEiView protein in PROSITE
PS00125 SER_THR_PHOSPHATASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q9SX52-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLDQWISKV KDGQHLSEDE LQLLCEYVKE ILIEESNVQP VNSPVTVCGD
60 70 80 90 100
IHGQFHDLMK LFQTGGHVPE TNYIFMGDFV DRGYNSLEVF TILLLLKARH
110 120 130 140 150
PANITLLRGN HESRQLTQVY GFYDECQRKY GNANAWRYCT DVFDYLTLSA
160 170 180 190 200
IIDGTVLCVH GGLSPDVRTI DQIRLIERNC EIPHEGPFCD LMWSDPEDIE
210 220 230 240 250
TWAVSPRGAG WLFGSRVTTE FNHINNLDLV CRAHQLVQEG LKYMFQDKGL
260 270 280 290 300
VTVWSAPNYC YRCGNVASIL SFNDNMEREV KFFTETEENN QMRGPRTGVP

YFL
Length:303
Mass (Da):34,819
Last modified:May 1, 2000 - v1
Checksum:i44598694DD92D626
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti68V → F in BAE98396 (Ref. 5) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007980 Genomic DNA Translation: AAD50050.1
CP002684 Genomic DNA Translation: AEE32541.1
AF428374 mRNA Translation: AAL16304.1
BT020404 mRNA Translation: AAV97795.1
AK226232 mRNA Translation: BAE98396.1
AY087422 mRNA Translation: AAM64970.1
PIRiH96539
RefSeqiNP_175454.1, NM_103920.4
UniGeneiAt.18962
At.5940

Genome annotation databases

EnsemblPlantsiAT1G50370.1; AT1G50370.1; AT1G50370
GeneIDi841459
GrameneiAT1G50370.1; AT1G50370.1; AT1G50370
KEGGiath:AT1G50370

Similar proteinsi

Entry informationi

Entry nameiFYPP1_ARATH
AccessioniPrimary (citable) accession number: Q9SX52
Secondary accession number(s): Q0WWV2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: May 1, 2000
Last modified: May 23, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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