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Protein

Developmentally-regulated G-protein 3

Gene

DRG3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Binds GDP and GTP, and has low GTPase activity in vitro.1 Publication

Caution

The nomenclature of the 3 Arabidopsis DRG genes is ambiguous; in the literature several gene names have been used for the same protein.Curated

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi72 – 79GTPPROSITE-ProRule annotation8
Nucleotide bindingi118 – 122GTPPROSITE-ProRule annotation5
Nucleotide bindingi249 – 252GTPPROSITE-ProRule annotation4

GO - Molecular functioni

  • GDP binding Source: TAIR
  • GTPase activity Source: TAIR
  • GTP binding Source: TAIR

Keywordsi

LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Developmentally-regulated G-protein 3
Short name:
AtDRG3
Alternative name(s):
Developmentally-regulated G-protein 1
Short name:
AtDRG1
Gene namesi
Name:DRG3
Synonyms:DRG1
Ordered Locus Names:At4g39520
ORF Names:F23K16.150
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G39520
TAIRilocus:2122536 AT4G39520

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004248331 – 369Developmentally-regulated G-protein 3Add BLAST369

Proteomic databases

PaxDbiQ9SVA6
PRIDEiQ9SVA6

Expressioni

Gene expression databases

ExpressionAtlasiQ9SVA6 baseline and differential
GenevisibleiQ9SVA6 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT4G39520.1

Structurei

3D structure databases

ProteinModelPortaliQ9SVA6
SMRiQ9SVA6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini66 – 291OBG-type GPROSITE-ProRule annotationAdd BLAST226

Sequence similaritiesi

Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1487 Eukaryota
COG1163 LUCA
HOGENOMiHOG000112078
InParanoidiQ9SVA6
OMAiSAKHPGQ
OrthoDBiEOG09360DX3
PhylomeDBiQ9SVA6

Family and domain databases

Gene3Di3.10.20.30, 1 hit
InterProiView protein in InterPro
IPR012675 Beta-grasp_dom_sf
IPR031167 G_OBG
IPR031662 GTP-binding_2
IPR006074 GTP1-OBG_CS
IPR006073 GTP_binding_domain
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR004095 TGS
IPR012676 TGS-like
PfamiView protein in Pfam
PF01926 MMR_HSR1, 1 hit
PF16897 MMR_HSR1_Xtn, 1 hit
PF02824 TGS, 1 hit
PRINTSiPR00326 GTP1OBG
SUPFAMiSSF52540 SSF52540, 1 hit
SSF81271 SSF81271, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51710 G_OBG, 1 hit
PS00905 GTP1_OBG, 1 hit

Sequencei

Sequence statusi: Complete.

Q9SVA6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTIMQKIKE IEDEMAKTQK NKATSHHLGL LKAKLAKLRR DLLAPPTKGG
60 70 80 90 100
GGGAGEGFDV TKSGDSRVGL VGFPSVGKST LLNKLTGTFS EVASYEFTTL
110 120 130 140 150
TCIPGVITYR GAKIQLLDLP GIIEGAKDGK GRGRQVISTA RTCNCILIVL
160 170 180 190 200
DAIKPITHKR LIEKELEGFG IRLNKEPPNL TFRKKDKGGI NLTSTVAVTH
210 220 230 240 250
LDLDTVKAIC GEYRMHNADI TLRYDATADD LIDVIEGSRI YMPCIYAVNK
260 270 280 290 300
IDSITLEELE ILDKLPHYCP VSAHLEWNLD GLLDKIWEYL DLTRIYTKPK
310 320 330 340 350
AMNPDYDDPV ILSSKKRTVE DFCIRIHKDM LKQFKYALVW GSSAKHKPQR
360
VGKEHELEDE DVVQIVKKI
Length:369
Mass (Da):41,144
Last modified:May 1, 2000 - v1
Checksum:i7235DC68F06DADFB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL078620 Genomic DNA Translation: CAB44687.1
AL161595 Genomic DNA Translation: CAB80615.1
CP002687 Genomic DNA Translation: AEE87081.1
AY035034 mRNA Translation: AAK59539.1
PIRiT09368
RefSeqiNP_195662.1, NM_120112.4
UniGeneiAt.3445

Genome annotation databases

EnsemblPlantsiAT4G39520.1; AT4G39520.1; AT4G39520
GeneIDi830106
GrameneiAT4G39520.1; AT4G39520.1; AT4G39520
KEGGiath:AT4G39520

Similar proteinsi

Entry informationi

Entry nameiDRG3_ARATH
AccessioniPrimary (citable) accession number: Q9SVA6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 22, 2014
Last sequence update: May 1, 2000
Last modified: April 25, 2018
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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