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Protein

Probable cysteine protease RDL5

Gene

RDL5

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Possesses protease activity in vitro.1 Publication

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei168 – 1681PROSITE-ProRule annotation
Active sitei304 – 3041PROSITE-ProRule annotation
Active sitei324 – 3241PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Thiol protease

Enzyme and pathway databases

BioCyciARA:AT4G11320-MONOMER.

Protein family/group databases

MEROPSiI29.003.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cysteine protease RDL5Curated (EC:3.4.22.-Curated)
Alternative name(s):
Cysteine protease 21 Publication
Short name:
AtCP21 Publication
Probable cysteine proteinase At4g11320Curated
RD21A-like protease 5Curated
Gene namesi
Name:RDL5Curated
Synonyms:CP21 Publication
Ordered Locus Names:At4g11320
ORF Names:F8L21.110
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRiAT4G11320.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323Sequence analysisAdd
BLAST
Propeptidei24 – 143120Activation peptideCuratedPRO_0000026465Add
BLAST
Chaini144 – 371228Probable cysteine protease RDL5PRO_0000026466Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi94 – 941N-linked (GlcNAc...)PROSITE-ProRule annotation
Disulfide bondi165 ↔ 206By similarity
Disulfide bondi199 ↔ 239By similarity
Disulfide bondi298 ↔ 349By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein, Zymogen

Proteomic databases

PaxDbiQ9SUS9.
PRIDEiQ9SUS9.

Expressioni

Tissue specificityi

Expressed in roots, inflorescences and siliques.1 Publication

Inductioni

By wounding.1 Publication

Gene expression databases

GenevisibleiQ9SUS9. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT4G11320.1.

Structurei

3D structure databases

ProteinModelPortaliQ9SUS9.
SMRiQ9SUS9. Positions 55-362.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase C1 family.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG1543. Eukaryota.
COG4870. LUCA.
HOGENOMiHOG000230773.
InParanoidiQ9SUS9.
OMAiKATDQKC.
OrthoDBiEOG093613VO.
PhylomeDBiQ9SUS9.

Family and domain databases

InterProiIPR025660. Pept_his_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
IPR013201. Prot_inhib_I29.
[Graphical view]
PANTHERiPTHR12411. PTHR12411. 1 hit.
PfamiPF08246. Inhibitor_I29. 1 hit.
PF00112. Peptidase_C1. 1 hit.
[Graphical view]
PRINTSiPR00705. PAPAIN.
SMARTiSM00848. Inhibitor_I29. 1 hit.
SM00645. Pept_C1. 1 hit.
[Graphical view]
PROSITEiPS00639. THIOL_PROTEASE_HIS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9SUS9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGYAKSAMLI FLLALVIASC ATAMDMSVVS SNDNHHVTAG PGRRQGIFDA
60 70 80 90 100
EATLMFESWM VKHGKVYDSV AEKERRLTIF EDNLRFITNR NAENLSYRLG
110 120 130 140 150
LNRFADLSLH EYGEICHGAD PRPPRNHVFM TSSNRYKTSD GDVLPKSVDW
160 170 180 190 200
RNEGAVTEVK DQGLCRSCWA FSTVGAVEGL NKIVTGELVT LSEQDLINCN
210 220 230 240 250
KENNGCGGGK VETAYEFIMN NGGLGTDNDY PYKALNGVCE GRLKEDNKNV
260 270 280 290 300
MIDGYENLPA NDEAALMKAV AHQPVTAVVD SSSREFQLYE SGVFDGTCGT
310 320 330 340 350
NLNHGVVVVG YGTENGRDYW IVKNSRGDTW GEAGYMKMAR NIANPRGLCG
360 370
IAMRASYPLK NSFSTDKVSV A
Length:371
Mass (Da):40,711
Last modified:May 1, 2000 - v1
Checksum:i6A8D5A5B8F7DD96D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL096882 Genomic DNA. Translation: CAB51416.1.
AL161531 Genomic DNA. Translation: CAB81233.1.
CP002687 Genomic DNA. Translation: AEE82996.1.
AY035055 mRNA. Translation: AAK59560.1.
AY051062 mRNA. Translation: AAK93739.1.
PIRiT13023.
RefSeqiNP_567377.1. NM_117203.3.
UniGeneiAt.25206.

Genome annotation databases

EnsemblPlantsiAT4G11320.1; AT4G11320.1; AT4G11320.
GeneIDi826734.
GrameneiAT4G11320.1; AT4G11320.1; AT4G11320.
KEGGiath:AT4G11320.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL096882 Genomic DNA. Translation: CAB51416.1.
AL161531 Genomic DNA. Translation: CAB81233.1.
CP002687 Genomic DNA. Translation: AEE82996.1.
AY035055 mRNA. Translation: AAK59560.1.
AY051062 mRNA. Translation: AAK93739.1.
PIRiT13023.
RefSeqiNP_567377.1. NM_117203.3.
UniGeneiAt.25206.

3D structure databases

ProteinModelPortaliQ9SUS9.
SMRiQ9SUS9. Positions 55-362.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT4G11320.1.

Protein family/group databases

MEROPSiI29.003.

Proteomic databases

PaxDbiQ9SUS9.
PRIDEiQ9SUS9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G11320.1; AT4G11320.1; AT4G11320.
GeneIDi826734.
GrameneiAT4G11320.1; AT4G11320.1; AT4G11320.
KEGGiath:AT4G11320.

Organism-specific databases

TAIRiAT4G11320.

Phylogenomic databases

eggNOGiKOG1543. Eukaryota.
COG4870. LUCA.
HOGENOMiHOG000230773.
InParanoidiQ9SUS9.
OMAiKATDQKC.
OrthoDBiEOG093613VO.
PhylomeDBiQ9SUS9.

Enzyme and pathway databases

BioCyciARA:AT4G11320-MONOMER.

Miscellaneous databases

PROiQ9SUS9.

Gene expression databases

GenevisibleiQ9SUS9. AT.

Family and domain databases

InterProiIPR025660. Pept_his_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
IPR013201. Prot_inhib_I29.
[Graphical view]
PANTHERiPTHR12411. PTHR12411. 1 hit.
PfamiPF08246. Inhibitor_I29. 1 hit.
PF00112. Peptidase_C1. 1 hit.
[Graphical view]
PRINTSiPR00705. PAPAIN.
SMARTiSM00848. Inhibitor_I29. 1 hit.
SM00645. Pept_C1. 1 hit.
[Graphical view]
PROSITEiPS00639. THIOL_PROTEASE_HIS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRDL5_ARATH
AccessioniPrimary (citable) accession number: Q9SUS9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 30, 2003
Last sequence update: May 1, 2000
Last modified: September 7, 2016
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. Peptidase families
    Classification of peptidase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.