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Protein

Reticulon-like protein B1

Gene

RTNLB1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Plays a role in the Agrobacterium-mediated plant transformation via its interaction with VirB2, the major component of the T-pilus.1 Publication

GO - Biological processi

  • endoplasmic reticulum tubular network organization Source: UniProtKB
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Reticulon-like protein B1
Short name:
AtRTNLB1
Alternative name(s):
VirB2-interacting protein 1
Gene namesi
Name:RTNLB1
Synonyms:BTI1
Ordered Locus Names:At4g23630
ORF Names:F9D16.100
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRiAT4G23630.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei99 – 119HelicalSequence analysisAdd BLAST21
Transmembranei120 – 140HelicalSequence analysisAdd BLAST21
Transmembranei194 – 214HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • endoplasmic reticulum Source: TAIR
  • endoplasmic reticulum membrane Source: TAIR
  • endoplasmic reticulum tubular network Source: UniProtKB
  • integral component of cytoplasmic side of endoplasmic reticulum membrane Source: UniProtKB
  • plasma membrane Source: TAIR
  • vacuole Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Endoplasmic reticulum, Membrane

Pathology & Biotechi

Disruption phenotypei

Shows reduced levels of Agrobacterium-mediated root transformation.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00003712822 – 275Reticulon-like protein B1Add BLAST274

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ9SUR3.
PRIDEiQ9SUR3.

PTM databases

iPTMnetiQ9SUR3.

Expressioni

Tissue specificityi

Predominantly expressed in root tissues.1 Publication

Inductioni

Up-regulated after Agrobacterium infection.1 Publication

Gene expression databases

GenevisibleiQ9SUR3. AT.

Interactioni

Subunit structurei

Interacts with VirB2.1 Publication

Protein-protein interaction databases

BioGridi13752. 6 interactors.
STRINGi3702.AT4G23630.1.

Structurei

3D structure databases

ProteinModelPortaliQ9SUR3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini89 – 274ReticulonPROSITE-ProRule annotationAdd BLAST186

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi40 – 68Ser-richAdd BLAST29

Sequence similaritiesi

Contains 1 reticulon domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1792. Eukaryota.
ENOG410XPKH. LUCA.
HOGENOMiHOG000237479.
InParanoidiQ9SUR3.
OMAiIHHGGDS.
OrthoDBiEOG09360L7O.
PhylomeDBiQ9SUR3.

Family and domain databases

InterProiIPR003388. Reticulon.
[Graphical view]
PfamiPF02453. Reticulon. 1 hit.
[Graphical view]
PROSITEiPS50845. RETICULON. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9SUR3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEEHKHDES VIAPEPAVEV VERESLMDKI SEKIHHGGDS SSSSSSSDDE
60 70 80 90 100
DEKKKTKKPS SPSSSMKSKV YRLFGREQPV HKVLGGGKPA DIFMWKNKKM
110 120 130 140 150
SGGVLGGATA AWVVFELMEY HLLTLLCHVM IVVLAVLFLW SNATMFINKS
160 170 180 190 200
PPKIPEVHIP EEPILQLASG LRIEINRGFS SLREIASGRD LKKFLIAIAG
210 220 230 240 250
LWVLSILGGC FNFLTLAYIA LVLLFTVPLA YDKYEDKVDP LGEKAMIELK
260 270
KQYAVLDEKV LSKIPLGPLK NKKKD
Length:275
Mass (Da):30,529
Last modified:May 1, 2000 - v1
Checksum:iEE165EFBB33258C6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL035394 Genomic DNA. Translation: CAA23029.1.
AL161559 Genomic DNA. Translation: CAB79318.1.
CP002687 Genomic DNA. Translation: AEE84787.1.
AY050321 mRNA. Translation: AAK91338.1.
AY133635 mRNA. Translation: AAM91465.1.
AY087881 mRNA. Translation: AAM65433.1.
PIRiT05595.
RefSeqiNP_194094.1. NM_118494.5.
UniGeneiAt.25485.

Genome annotation databases

EnsemblPlantsiAT4G23630.1; AT4G23630.1; AT4G23630.
GeneIDi828463.
GrameneiAT4G23630.1; AT4G23630.1; AT4G23630.
KEGGiath:AT4G23630.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL035394 Genomic DNA. Translation: CAA23029.1.
AL161559 Genomic DNA. Translation: CAB79318.1.
CP002687 Genomic DNA. Translation: AEE84787.1.
AY050321 mRNA. Translation: AAK91338.1.
AY133635 mRNA. Translation: AAM91465.1.
AY087881 mRNA. Translation: AAM65433.1.
PIRiT05595.
RefSeqiNP_194094.1. NM_118494.5.
UniGeneiAt.25485.

3D structure databases

ProteinModelPortaliQ9SUR3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi13752. 6 interactors.
STRINGi3702.AT4G23630.1.

PTM databases

iPTMnetiQ9SUR3.

Proteomic databases

PaxDbiQ9SUR3.
PRIDEiQ9SUR3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G23630.1; AT4G23630.1; AT4G23630.
GeneIDi828463.
GrameneiAT4G23630.1; AT4G23630.1; AT4G23630.
KEGGiath:AT4G23630.

Organism-specific databases

TAIRiAT4G23630.

Phylogenomic databases

eggNOGiKOG1792. Eukaryota.
ENOG410XPKH. LUCA.
HOGENOMiHOG000237479.
InParanoidiQ9SUR3.
OMAiIHHGGDS.
OrthoDBiEOG09360L7O.
PhylomeDBiQ9SUR3.

Miscellaneous databases

PROiQ9SUR3.

Gene expression databases

GenevisibleiQ9SUR3. AT.

Family and domain databases

InterProiIPR003388. Reticulon.
[Graphical view]
PfamiPF02453. Reticulon. 1 hit.
[Graphical view]
PROSITEiPS50845. RETICULON. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRTNLA_ARATH
AccessioniPrimary (citable) accession number: Q9SUR3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: May 1, 2000
Last modified: November 30, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.