Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosphatidylinositol 4-phosphate 5-kinase 7

Gene

PIP5K7

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT1G10900-MONOMER
ReactomeiR-ATH-1660499 Synthesis of PIPs at the plasma membrane
R-ATH-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
R-ATH-8856828 Clathrin-mediated endocytosis

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphatidylinositol 4-phosphate 5-kinase 7 (EC:2.7.1.68)
Short name:
AtPIP5K7
Alternative name(s):
1-phosphatidylinositol 4-phosphate kinase 7
Diphosphoinositide kinase 7
Short name:
AtP5K2
PtdIns(4)P-5-kinase 7
Gene namesi
Name:PIP5K7
Synonyms:P5K2
Ordered Locus Names:At1g10900
ORF Names:T19D16.18
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G10900
TAIRilocus:2197454 AT1G10900

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001854791 – 754Phosphatidylinositol 4-phosphate 5-kinase 7Add BLAST754

Proteomic databases

PaxDbiQ9SUI2

PTM databases

iPTMnetiQ9SUI2

Expressioni

Gene expression databases

ExpressionAtlasiQ9SUI2 baseline and differential
GenevisibleiQ9SUI2 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G10900.1

Structurei

3D structure databases

ProteinModelPortaliQ9SUI2
SMRiQ9SUI2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati16 – 38MORN 1Add BLAST23
Repeati39 – 61MORN 2Add BLAST23
Repeati62 – 84MORN 3Add BLAST23
Repeati85 – 107MORN 4Add BLAST23
Repeati108 – 130MORN 5Add BLAST23
Repeati131 – 153MORN 6Add BLAST23
Repeati154 – 176MORN 7Add BLAST23
Repeati177 – 198MORN 8Add BLAST22
Domaini329 – 750PIPKPROSITE-ProRule annotationAdd BLAST422

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni710 – 731Activation loopBy similarityAdd BLAST22

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG0229 Eukaryota
COG4642 LUCA
COG5253 LUCA
HOGENOMiHOG000193875
InParanoidiQ9SUI2
KOiK00889
OMAiKHGMGTM
OrthoDBiEOG0936025Q
PhylomeDBiQ9SUI2

Family and domain databases

Gene3Di3.30.800.10, 1 hit
3.30.810.10, 2 hits
InterProiView protein in InterPro
IPR003409 MORN
IPR017163 PIno-4-P-5_kinase_pln
IPR023610 PInositol-4-P-5-kinase
IPR027483 PInositol-4-P-5-kinase_C
IPR002498 PInositol-4-P-5-kinase_core
IPR027484 PInositol-4-P-5-kinase_N
PANTHERiPTHR23086 PTHR23086, 1 hit
PfamiView protein in Pfam
PF02493 MORN, 8 hits
PF01504 PIP5K, 1 hit
PIRSFiPIRSF037274 PIP5K_plant_prd, 1 hit
SMARTiView protein in SMART
SM00698 MORN, 8 hits
SM00330 PIPKc, 1 hit
PROSITEiView protein in PROSITE
PS51455 PIPK, 1 hit

Sequencei

Sequence statusi: Complete.

Q9SUI2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDMRSGDREF PNGDFYSGEV KGIIPNGKGK YAWSDGTIYE GDWDEGKISG
60 70 80 90 100
KGKLIWSSGA KYEGDFSGGY LHGFGTMTSP DESVYSGAWR MNVRHGLGRK
110 120 130 140 150
EYCNSDLYDG LWKEGLQDGR GSYSWTNGNR YIGNWKKGKM CERGVMRWEN
160 170 180 190 200
GDLYDGFWLN GFRHGSGVYK FADGCLYYGT WSRGLKDGKG VFYPAGTKQP
210 220 230 240 250
SLKKWCRSLE YDDTGKFVLS RSASVNVEEL RSLNTVTQSL SVKTSAGETT
260 270 280 290 300
CDPPRDFTCH GPVSKSARFS GSGQSEGQDK NRIVYEREYM QGVLIRETIM
310 320 330 340 350
SSVDRSHKIK PPNRPREVRA RSLMTFLRGE HNYYLMLNLQ LGIRYTVGKI
360 370 380 390 400
TPVPRREVRA SDFGKNARTK MFFPRDGSNF TPPHKSVDFS WKDYCPMVFR
410 420 430 440 450
NLRQMFKLDA AEYMMSICGD DGLTEISSPG KSGSIFYLSH DDRFVIKTLK
460 470 480 490 500
KSELQVLLRM LPKYYEHVGD HENTLITKFF GVHRITLKWG KKVRFVVMGN
510 520 530 540 550
MFCTELKIHR RYDLKGSTQG RFTEKIKIQE KTTLKDLDLA YEFHMDKLLR
560 570 580 590 600
EALFKQIYLD CSFLESLNII DYSLLLGLHF RAPGQLNDIL EPPNAMSDQE
610 620 630 640 650
SVSSVDVGLT QEHSIPPKGL LLVTHEPNSV NTAPGPHIRG STLRAFSVGE
660 670 680 690 700
QEVDLILPGT ARLRVQLGVN MPAQAHHKLI EDKEESATIE LFEVYDVVVY
710 720 730 740 750
MGIIDILQEY NTKKKVEHTC KSLQYDPMTI SVTEPSTYSK RFVNFLHKVF

PEER
Length:754
Mass (Da):85,955
Last modified:May 1, 2000 - v1
Checksum:iD2310E6AABBA4F00
GO

Sequence cautioni

The sequence AAB65487 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ009782 mRNA Translation: CAB53377.1
U95973 Genomic DNA Translation: AAB65487.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE28661.1
CP002684 Genomic DNA Translation: ANM60004.1
CP002684 Genomic DNA Translation: ANM60005.1
AY062718 mRNA Translation: AAL32796.1
BT010342 mRNA Translation: AAQ56785.1
PIRiG86242
RefSeqiNP_001322318.1, NM_001331939.1
NP_001322319.1, NM_001331940.1
NP_172559.2, NM_100965.5
UniGeneiAt.485

Genome annotation databases

EnsemblPlantsiAT1G10900.1; AT1G10900.1; AT1G10900
AT1G10900.2; AT1G10900.2; AT1G10900
AT1G10900.3; AT1G10900.3; AT1G10900
GeneIDi837633
GrameneiAT1G10900.1; AT1G10900.1; AT1G10900
AT1G10900.2; AT1G10900.2; AT1G10900
AT1G10900.3; AT1G10900.3; AT1G10900
KEGGiath:AT1G10900

Similar proteinsi

Entry informationi

Entry nameiPI5K7_ARATH
AccessioniPrimary (citable) accession number: Q9SUI2
Secondary accession number(s): O04095
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: May 1, 2000
Last modified: April 25, 2018
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health