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Q9SUI2 (PI5K7_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 96. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphatidylinositol 4-phosphate 5-kinase 7

Short name=AtPIP5K7
EC=2.7.1.68
Alternative name(s):
1-phosphatidylinositol 4-phosphate kinase 7
Diphosphoinositide kinase 7
Short name=AtP5K2
PtdIns(4)P-5-kinase 7
Gene names
Name:PIP5K7
Synonyms:P5K2
Ordered Locus Names:At1g10900
ORF Names:T19D16.18
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length754 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.

Sequence similarities

Contains 8 MORN repeats.

Contains 1 PIPK domain.

Sequence caution

The sequence AAB65487.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
   DomainRepeat
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentplasma membrane

Inferred from direct assay PubMed 17317660. Source: TAIR

   Molecular_function1-phosphatidylinositol-4-phosphate 5-kinase activity

Inferred from electronic annotation. Source: UniProtKB-EC

ATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 754754Phosphatidylinositol 4-phosphate 5-kinase 7
PRO_0000185479

Regions

Repeat16 – 3823MORN 1
Repeat39 – 6123MORN 2
Repeat62 – 8423MORN 3
Repeat85 – 10723MORN 4
Repeat108 – 13023MORN 5
Repeat131 – 15323MORN 6
Repeat154 – 17623MORN 7
Repeat177 – 19822MORN 8
Domain329 – 750422PIPK
Region710 – 73122Activation loop By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9SUI2 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: D2310E6AABBA4F00

FASTA75485,955
        10         20         30         40         50         60 
MDMRSGDREF PNGDFYSGEV KGIIPNGKGK YAWSDGTIYE GDWDEGKISG KGKLIWSSGA 

        70         80         90        100        110        120 
KYEGDFSGGY LHGFGTMTSP DESVYSGAWR MNVRHGLGRK EYCNSDLYDG LWKEGLQDGR 

       130        140        150        160        170        180 
GSYSWTNGNR YIGNWKKGKM CERGVMRWEN GDLYDGFWLN GFRHGSGVYK FADGCLYYGT 

       190        200        210        220        230        240 
WSRGLKDGKG VFYPAGTKQP SLKKWCRSLE YDDTGKFVLS RSASVNVEEL RSLNTVTQSL 

       250        260        270        280        290        300 
SVKTSAGETT CDPPRDFTCH GPVSKSARFS GSGQSEGQDK NRIVYEREYM QGVLIRETIM 

       310        320        330        340        350        360 
SSVDRSHKIK PPNRPREVRA RSLMTFLRGE HNYYLMLNLQ LGIRYTVGKI TPVPRREVRA 

       370        380        390        400        410        420 
SDFGKNARTK MFFPRDGSNF TPPHKSVDFS WKDYCPMVFR NLRQMFKLDA AEYMMSICGD 

       430        440        450        460        470        480 
DGLTEISSPG KSGSIFYLSH DDRFVIKTLK KSELQVLLRM LPKYYEHVGD HENTLITKFF 

       490        500        510        520        530        540 
GVHRITLKWG KKVRFVVMGN MFCTELKIHR RYDLKGSTQG RFTEKIKIQE KTTLKDLDLA 

       550        560        570        580        590        600 
YEFHMDKLLR EALFKQIYLD CSFLESLNII DYSLLLGLHF RAPGQLNDIL EPPNAMSDQE 

       610        620        630        640        650        660 
SVSSVDVGLT QEHSIPPKGL LLVTHEPNSV NTAPGPHIRG STLRAFSVGE QEVDLILPGT 

       670        680        690        700        710        720 
ARLRVQLGVN MPAQAHHKLI EDKEESATIE LFEVYDVVVY MGIIDILQEY NTKKKVEHTC 

       730        740        750 
KSLQYDPMTI SVTEPSTYSK RFVNFLHKVF PEER 

« Hide

References

« Hide 'large scale' references
[1]"Molecular aspects of AtP5K2 in stomatal guard cells a phosphatidyinositol-4-phosphate 5-kinase."
Elge S., Mueller-Roeber B.
Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Columbia.
Tissue: Seedling hypocotyl.
[2]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[4]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[5]"Inositol phospholipid metabolism in Arabidopsis. Characterized and putative isoforms of inositol phospholipid kinase and phosphoinositide-specific phospholipase C."
Mueller-Roeber B., Pical C.
Plant Physiol. 130:22-46(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
[6]"Large-scale Arabidopsis phosphoproteome profiling reveals novel chloroplast kinase substrates and phosphorylation networks."
Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A., Grossmann J., Gruissem W., Baginsky S.
Plant Physiol. 150:889-903(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ009782 mRNA. Translation: CAB53377.1.
U95973 Genomic DNA. Translation: AAB65487.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE28661.1.
AY062718 mRNA. Translation: AAL32796.1.
BT010342 mRNA. Translation: AAQ56785.1.
PIRG86242.
RefSeqNP_172559.2. NM_100965.4.
UniGeneAt.485.

3D structure databases

ProteinModelPortalQ9SUI2.
SMRQ9SUI2. Positions 339-579.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PaxDbQ9SUI2.
PRIDEQ9SUI2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G10900.1; AT1G10900.1; AT1G10900.
GeneID837633.
KEGGath:AT1G10900.

Organism-specific databases

GeneFarm5100.
TAIRAT1G10900.

Phylogenomic databases

eggNOGCOG4642.
HOGENOMHOG000193875.
InParanoidQ9SUI2.
KOK00889.
OMALEPPNAM.
PhylomeDBQ9SUI2.

Enzyme and pathway databases

BioCycARA:AT1G10900-MONOMER.

Gene expression databases

GenevestigatorQ9SUI2.

Family and domain databases

Gene3D3.30.800.10. 1 hit.
3.30.810.10. 2 hits.
InterProIPR003409. MORN.
IPR017163. PIno-4-P-5_kinase_pln.
IPR023610. PInositol-4-P-5-kinase.
IPR027483. PInositol-4-P-5-kinase_C.
IPR002498. PInositol-4-P-5-kinase_core.
IPR027484. PInositol-4-P-5-kinase_N.
IPR016034. PInositol-4P-5-kinase_core_sub.
[Graphical view]
PANTHERPTHR23086. PTHR23086. 1 hit.
PfamPF02493. MORN. 8 hits.
PF01504. PIP5K. 1 hit.
[Graphical view]
PIRSFPIRSF037274. PIP5K_plant_prd. 1 hit.
SMARTSM00698. MORN. 8 hits.
SM00330. PIPKc. 1 hit.
[Graphical view]
PROSITEPS51455. PIPK. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePI5K7_ARATH
AccessionPrimary (citable) accession number: Q9SUI2
Secondary accession number(s): O04095
Entry history
Integrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: May 1, 2000
Last modified: June 11, 2014
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names