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Reviewed, UniProtKB/Swiss-Prot Q9STS1 (BADH2_ARATH)

Last modified November 3, 2009. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Betaine aldehyde dehydrogenase 2, mitochondrial
      Short name=BADH
    EC=1.2.1.8
Alternative name(s):
    Aldehyde dehydrogenase family 10 member A9
Gene names
Name: ALDH10A9
Ordered Locus Names: At3g48170
ORF Names: T24C20.50
OrganismArabidopsis thaliana (Mouse-ear cress) [Complete proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis

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Protein attributes

Sequence length503 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Catalytic activity

Betaine aldehyde + NAD+ + H2O = betaine + NADH.

Subunit structure

Homodimer By similarity.

Subcellular location

Mitochondrion Potential.

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

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Ontologies

Keywords
   Cellular componentMitochondrion
   DomainTransit peptide
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentmitochondrion

Inferred from electronic annotation. Source: UniProtKB-SubCell

peroxisome

Inferred from direct assay. Source: TAIR

   Molecular functionbetaine-aldehyde dehydrogenase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 6565Mitochondrion Potential
Chain66 – 503438Betaine aldehyde dehydrogenase 2, mitochondrial
PRO_0000256063

Regions

Nucleotide binding238 – 2436NAD By similarity

Sites

Active site2601Proton acceptor By similarity
Active site2941Nucleophile By similarity
Site1621Transition state stabilizer By similarity

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Sequences

Sequence LengthMass (Da)Tools
Q9STS1-1 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 7E17AE86E9F2784C

FASTA50354,918
        10         20         30         40         50         60 
MAITVPRRQL FIGGQWTEPV LRKTLPVVNP ATEDIIGYIP AATSEDVELA VEAARKAFTR 

        70         80         90        100        110        120 
NNGKDWARAT GAVRAKYLRA IAAKVIERKS ELANLEAIDC GKPLDEAAWD MDDVAGCFEY 

       130        140        150        160        170        180 
YADLAEGLDA KQKTPLSLPM DTFKGYILKE PIGVVGMITP WNYPLLMAVW KVAPSLAAGC 

       190        200        210        220        230        240 
TAILKPSELA SLTCLELADI CREVGLPPGV LNILTGLGTE AGAPLASHPH VDKIVFTGST 

       250        260        270        280        290        300 
TTGSSIMTSA AKLVKPVSLE LGGKSPIIVF DDVDIDKAVE WTMFGCFWTN GQICSATSRL 

       310        320        330        340        350        360 
LVHERIADEF LDKLVKWTKN IKISDPFEEG CRLGPVVSKG QYERVLKFVS NARNEGATVL 

       370        380        390        400        410        420 
CGGVRPEHLK KGYFVEPAIV SNVTTSMEIW REEVFGPALC VKTFSTEDEA IQLANDSQYG 

       430        440        450        460        470        480 
LAGAVLSNDL ERCDRVSKAF QAGIVWVNCS QPCFCQAPWG GTKRSGFGRE LGEWGLENYL 

       490        500 
SVKQVTQYIS DEPWGWYKPP SKL

« Hide

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References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana."
Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F. expand/collapse author list , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
Nature 408:820-822(2000) [PubMed: 11130713] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed: 14593172] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[3]"The Arabidopsis thaliana transcribed genome: the GDR cDNA program."
Raynal M., Grellet F., Laudie M., Meyer Y., Cooke R., Delseny M.
Submitted (FEB-1994) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 417-503.
Strain: cv. Columbia.
Tissue: Seed.
[4]"The ALDH gene superfamily of Arabidopsis."
Kirch H.-H., Bartels D., Wei Y., Schnable P.S., Wood A.J.
Trends Plant Sci. 9:371-377(2004) [PubMed: 15358267] [Abstract]
Cited for: NOMENCLATURE.
+Additional computationally mapped references.

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Cross-references

Sequence databases

AL096856 Genomic DNA. Translation: CAB51064.1.
AF370333 mRNA. Translation: AAK44148.1.
AY062987 mRNA. Translation: AAL34161.1.
Z29888 mRNA. Translation: CAA82832.1.
IPIIPI00545825.
PIRT13006.
RefSeqNP_190400.1.
UniGeneAt.1613

3D structure databases

HSSPHSSP built from PDB template 1O04 based on UniProtKB P05091.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ9STS1.

Proteomic databases

PRIDEQ9STS1.

Genome annotation databases

GeneID823972.
GenomeReviewsGene locus AT3G48170 in contig BA000014_GR.
KEGGath:AT3G48170.
NMPDRfig|3702.1.peg.16052.

Organism-specific databases

TAIRAt3g48170.

Phylogenomic databases

OMARCERISK.

Enzyme and pathway databases

BRENDA1.2.1.8. 302.

Gene expression databases

ArrayExpressQ9STS1.
GenevestigatorQ9STS1.
GermOnlineAT3G48170. Arabidopsis thaliana.

Family and domain databases

InterProIPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH.
[Graphical view]
Gene3DG3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
PANTHERPTHR11699. Aldehyde_dehyd. 1 hit.
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameBADH2_ARATH
AccessionPrimary (citable) accession number: Q9STS1
Secondary accession number(s): Q42237
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: May 1, 2000
Last modified: November 3, 2009
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

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Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents