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Q9STS1

- BADH2_ARATH

UniProt

Q9STS1 - BADH2_ARATH

Protein

Betaine aldehyde dehydrogenase 2, mitochondrial

Gene

ALDH10A9

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 92 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Betaine aldehyde + NAD+ + H2O = betaine + NADH.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei162 – 1621Transition state stabilizerBy similarity
    Active sitei260 – 2601Proton acceptorPROSITE-ProRule annotation
    Active sitei294 – 2941NucleophilePROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi238 – 2436NADBy similarity

    GO - Molecular functioni

    1. aldehyde dehydrogenase (NAD) activity Source: TAIR
    2. betaine-aldehyde dehydrogenase activity Source: TAIR

    GO - Biological processi

    1. oxidation-reduction process Source: TAIR
    2. response to abscisic acid Source: TAIR
    3. response to water deprivation Source: TAIR

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    NAD

    Enzyme and pathway databases

    BioCyciARA:AT3G48170-MONOMER.
    MetaCyc:AT3G48170-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Betaine aldehyde dehydrogenase 2, mitochondrial (EC:1.2.1.8)
    Short name:
    BADH
    Alternative name(s):
    Aldehyde dehydrogenase family 10 member A9
    Gene namesi
    Name:ALDH10A9
    Ordered Locus Names:At3g48170
    ORF Names:T24C20.50
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 3

    Organism-specific databases

    TAIRiAT3G48170.

    Subcellular locationi

    GO - Cellular componenti

    1. mitochondrion Source: UniProtKB-SubCell
    2. peroxisome Source: TAIR

    Keywords - Cellular componenti

    Mitochondrion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transit peptidei1 – 6565MitochondrionSequence AnalysisAdd
    BLAST
    Chaini66 – 503438Betaine aldehyde dehydrogenase 2, mitochondrialPRO_0000256063Add
    BLAST

    Proteomic databases

    PaxDbiQ9STS1.
    PRIDEiQ9STS1.

    Expressioni

    Gene expression databases

    ArrayExpressiQ9STS1.
    GenevestigatoriQ9STS1.

    Interactioni

    Subunit structurei

    Homodimer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ9STS1.
    SMRiQ9STS1. Positions 5-503.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the aldehyde dehydrogenase family.Curated

    Keywords - Domaini

    Transit peptide

    Phylogenomic databases

    eggNOGiCOG1012.
    HOGENOMiHOG000271505.
    InParanoidiQ9STS1.
    KOiK00130.
    OMAiAEYQEHK.
    PhylomeDBiQ9STS1.

    Family and domain databases

    Gene3Di3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProiIPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR016160. Ald_DH_CS_CYS.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view]
    PfamiPF00171. Aldedh. 1 hit.
    [Graphical view]
    SUPFAMiSSF53720. SSF53720. 1 hit.
    PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
    PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q9STS1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAITVPRRQL FIGGQWTEPV LRKTLPVVNP ATEDIIGYIP AATSEDVELA    50
    VEAARKAFTR NNGKDWARAT GAVRAKYLRA IAAKVIERKS ELANLEAIDC 100
    GKPLDEAAWD MDDVAGCFEY YADLAEGLDA KQKTPLSLPM DTFKGYILKE 150
    PIGVVGMITP WNYPLLMAVW KVAPSLAAGC TAILKPSELA SLTCLELADI 200
    CREVGLPPGV LNILTGLGTE AGAPLASHPH VDKIVFTGST TTGSSIMTSA 250
    AKLVKPVSLE LGGKSPIIVF DDVDIDKAVE WTMFGCFWTN GQICSATSRL 300
    LVHERIADEF LDKLVKWTKN IKISDPFEEG CRLGPVVSKG QYERVLKFVS 350
    NARNEGATVL CGGVRPEHLK KGYFVEPAIV SNVTTSMEIW REEVFGPALC 400
    VKTFSTEDEA IQLANDSQYG LAGAVLSNDL ERCDRVSKAF QAGIVWVNCS 450
    QPCFCQAPWG GTKRSGFGRE LGEWGLENYL SVKQVTQYIS DEPWGWYKPP 500
    SKL 503
    Length:503
    Mass (Da):54,918
    Last modified:May 1, 2000 - v1
    Checksum:i7E17AE86E9F2784C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL096856 Genomic DNA. Translation: CAB51064.1.
    CP002686 Genomic DNA. Translation: AEE78376.1.
    AF370333 mRNA. Translation: AAK44148.1.
    AY062987 mRNA. Translation: AAL34161.1.
    Z29888 mRNA. Translation: CAA82832.1.
    PIRiT13006.
    RefSeqiNP_190400.1. NM_114686.3.
    UniGeneiAt.1613.

    Genome annotation databases

    EnsemblPlantsiAT3G48170.1; AT3G48170.1; AT3G48170.
    GeneIDi823972.
    KEGGiath:AT3G48170.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL096856 Genomic DNA. Translation: CAB51064.1 .
    CP002686 Genomic DNA. Translation: AEE78376.1 .
    AF370333 mRNA. Translation: AAK44148.1 .
    AY062987 mRNA. Translation: AAL34161.1 .
    Z29888 mRNA. Translation: CAA82832.1 .
    PIRi T13006.
    RefSeqi NP_190400.1. NM_114686.3.
    UniGenei At.1613.

    3D structure databases

    ProteinModelPortali Q9STS1.
    SMRi Q9STS1. Positions 5-503.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PaxDbi Q9STS1.
    PRIDEi Q9STS1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT3G48170.1 ; AT3G48170.1 ; AT3G48170 .
    GeneIDi 823972.
    KEGGi ath:AT3G48170.

    Organism-specific databases

    TAIRi AT3G48170.

    Phylogenomic databases

    eggNOGi COG1012.
    HOGENOMi HOG000271505.
    InParanoidi Q9STS1.
    KOi K00130.
    OMAi AEYQEHK.
    PhylomeDBi Q9STS1.

    Enzyme and pathway databases

    BioCyci ARA:AT3G48170-MONOMER.
    MetaCyc:AT3G48170-MONOMER.

    Gene expression databases

    ArrayExpressi Q9STS1.
    Genevestigatori Q9STS1.

    Family and domain databases

    Gene3Di 3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProi IPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR016160. Ald_DH_CS_CYS.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view ]
    Pfami PF00171. Aldedh. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53720. SSF53720. 1 hit.
    PROSITEi PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
    PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana."
      Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F.
      , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
      Nature 408:820-822(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    4. "The Arabidopsis thaliana transcribed genome: the GDR cDNA program."
      Raynal M., Grellet F., Laudie M., Meyer Y., Cooke R., Delseny M.
      Submitted (FEB-1994) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 417-503.
      Strain: cv. Columbia.
      Tissue: Seed.
    5. Cited for: NOMENCLATURE.

    Entry informationi

    Entry nameiBADH2_ARATH
    AccessioniPrimary (citable) accession number: Q9STS1
    Secondary accession number(s): Q42237
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 31, 2006
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 92 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3