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Q9STS1 (BADH2_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Betaine aldehyde dehydrogenase 2, mitochondrial
Short name=BADH
EC=1.2.1.8
Alternative name(s):
Aldehyde dehydrogenase family 10 member A9
Gene names
Name:ALDH10A9
Ordered Locus Names:At3g48170
ORF Names:T24C20.50
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length503 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

Betaine aldehyde + NAD+ + H2O = betaine + NADH.

Subunit structure

Homodimer By similarity.

Subcellular location

Mitochondrion Potential.

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 6565Mitochondrion Potential
Chain66 – 503438Betaine aldehyde dehydrogenase 2, mitochondrial
PRO_0000256063

Regions

Nucleotide binding238 – 2436NAD By similarity

Sites

Active site2601Proton acceptor By similarity
Active site2941Nucleophile By similarity
Site1621Transition state stabilizer By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9STS1 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 7E17AE86E9F2784C

FASTA50354,918
        10         20         30         40         50         60 
MAITVPRRQL FIGGQWTEPV LRKTLPVVNP ATEDIIGYIP AATSEDVELA VEAARKAFTR 

        70         80         90        100        110        120 
NNGKDWARAT GAVRAKYLRA IAAKVIERKS ELANLEAIDC GKPLDEAAWD MDDVAGCFEY 

       130        140        150        160        170        180 
YADLAEGLDA KQKTPLSLPM DTFKGYILKE PIGVVGMITP WNYPLLMAVW KVAPSLAAGC 

       190        200        210        220        230        240 
TAILKPSELA SLTCLELADI CREVGLPPGV LNILTGLGTE AGAPLASHPH VDKIVFTGST 

       250        260        270        280        290        300 
TTGSSIMTSA AKLVKPVSLE LGGKSPIIVF DDVDIDKAVE WTMFGCFWTN GQICSATSRL 

       310        320        330        340        350        360 
LVHERIADEF LDKLVKWTKN IKISDPFEEG CRLGPVVSKG QYERVLKFVS NARNEGATVL 

       370        380        390        400        410        420 
CGGVRPEHLK KGYFVEPAIV SNVTTSMEIW REEVFGPALC VKTFSTEDEA IQLANDSQYG 

       430        440        450        460        470        480 
LAGAVLSNDL ERCDRVSKAF QAGIVWVNCS QPCFCQAPWG GTKRSGFGRE LGEWGLENYL 

       490        500 
SVKQVTQYIS DEPWGWYKPP SKL

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana."
Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F. expand/collapse author list , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
Nature 408:820-822(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"The Arabidopsis thaliana transcribed genome: the GDR cDNA program."
Raynal M., Grellet F., Laudie M., Meyer Y., Cooke R., Delseny M.
Submitted (FEB-1994) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 417-503.
Strain: cv. Columbia.
Tissue: Seed.
[5]"The ALDH gene superfamily of Arabidopsis."
Kirch H.-H., Bartels D., Wei Y., Schnable P.S., Wood A.J.
Trends Plant Sci. 9:371-377(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NOMENCLATURE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL096856 Genomic DNA. Translation: CAB51064.1.
CP002686 Genomic DNA. Translation: AEE78376.1.
AF370333 mRNA. Translation: AAK44148.1.
AY062987 mRNA. Translation: AAL34161.1.
Z29888 mRNA. Translation: CAA82832.1.
IPIIPI00545825.
PIRT13006.
RefSeqNP_190400.1. NM_114686.3.
UniGeneAt.1613.

3D structure databases

HSSPHSSP built from PDB template 1ZUM based on UniProtKB P05091.
ProteinModelPortalQ9STS1.
SMRQ9STS1. Positions 5-503.
ModBaseSearch...

Proteomic databases

PaxDbQ9STS1.
PRIDEQ9STS1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT3G48170.1; AT3G48170.1; AT3G48170.
GeneID823972.
KEGGath:AT3G48170.

Organism-specific databases

TAIRAt3g48170.

Phylogenomic databases

eggNOGCOG1012.
HOGENOMHOG000271505.
InParanoidQ9STS1.
KOK00130.
OMAKAVEWTM.
PhylomeDBQ9STS1.
ProtClustDBPLN02467.

Enzyme and pathway databases

BioCycARA:AT3G48170-MONOMER.
MetaCyc:AT3G48170-MONOMER.

Gene expression databases

ArrayExpressQ9STS1.
GenevestigatorQ9STS1.
GermOnlineAT3G48170. Arabidopsis thaliana.

Family and domain databases

Gene3D3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBADH2_ARATH
AccessionPrimary (citable) accession number: Q9STS1
Secondary accession number(s): Q42237
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: May 1, 2000
Last modified: May 1, 2013
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents