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Protein

KDEL-tailed cysteine endopeptidase CEP3

Gene

CEP3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Involved in the final stage of developmental programmed cell death and in intercalation of new cells. Cleaves extensins, thus probably supporting the final cell collapse.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei150PROSITE-ProRule annotation1
Active sitei287PROSITE-ProRule annotation1
Active sitei308PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Thiol protease

Protein family/group databases

MEROPSiC01.A02

Names & Taxonomyi

Protein namesi
Recommended name:
KDEL-tailed cysteine endopeptidase CEP3 (EC:3.4.22.-)
Gene namesi
Name:CEP31 Publication
Ordered Locus Names:At3g48350Imported
ORF Names:T29H11.130Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G48350
TAIRilocus:505006391 AT3G48350

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
PropeptideiPRO_000043632321 – 125Activation peptideCuratedAdd BLAST105
ChainiPRO_0000403791126 – 364KDEL-tailed cysteine endopeptidase CEP3Add BLAST239

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi122N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Disulfide bondi147 ↔ 189By similarity
Disulfide bondi181 ↔ 223By similarity
Disulfide bondi281 ↔ 333By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein, Zymogen

Proteomic databases

PaxDbiQ9STL5
PRIDEiQ9STL5

Expressioni

Tissue specificityi

Expressed in roots, stems, flowers, buds, green siliques, trichomes and near the stomata of cotyledons but not of true leaves. Found at the hypocotyl-root transition zone, in the vascular tissue, along primary and lateral roots, but not in root tips. Never found in the abscission zone of flower organs.1 Publication

Developmental stagei

Expressed during silique development, but limited to the carpels and the pedicel.1 Publication

Gene expression databases

ExpressionAtlasiQ9STL5 baseline and differential
GenevisibleiQ9STL5 AT

Interactioni

Protein-protein interaction databases

BioGridi9312, 1 interactor
STRINGi3702.AT3G48350.1

Structurei

3D structure databases

ProteinModelPortaliQ9STL5
SMRiQ9STL5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi361 – 364Prevents secretion from ERPROSITE-ProRule annotation4

Sequence similaritiesi

Belongs to the peptidase C1 family.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG1543 Eukaryota
COG4870 LUCA
HOGENOMiHOG000230773
InParanoidiQ9STL5
KOiK16292
OMAiKWRSHHT
OrthoDBiEOG09360FGY
PhylomeDBiQ9STL5

Family and domain databases

InterProiView protein in InterPro
IPR025661 Pept_asp_AS
IPR000169 Pept_cys_AS
IPR025660 Pept_his_AS
IPR013128 Peptidase_C1A
IPR000668 Peptidase_C1A_C
IPR013201 Prot_inhib_I29
PANTHERiPTHR12411 PTHR12411, 1 hit
PfamiView protein in Pfam
PF08246 Inhibitor_I29, 1 hit
PF00112 Peptidase_C1, 1 hit
PRINTSiPR00705 PAPAIN
SMARTiView protein in SMART
SM00848 Inhibitor_I29, 1 hit
SM00645 Pept_C1, 1 hit
PROSITEiView protein in PROSITE
PS00014 ER_TARGET, 1 hit
PS00640 THIOL_PROTEASE_ASN, 1 hit
PS00139 THIOL_PROTEASE_CYS, 1 hit
PS00639 THIOL_PROTEASE_HIS, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9STL5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLFFIVLIS FLSLLQASKG FDFDEKELET EENVWKLYER WRGHHSVSRA
60 70 80 90 100
SHEAIKRFNV FRHNVLHVHR TNKKNKPYKL KINRFADITH HEFRSSYAGS
110 120 130 140 150
NVKHHRMLRG PKRGSGGFMY ENVTRVPSSV DWREKGAVTE VKNQQDCGSC
160 170 180 190 200
WAFSTVAAVE GINKIRTNKL VSLSEQELVD CDTEENQGCA GGLMEPAFEF
210 220 230 240 250
IKNNGGIKTE ETYPYDSSDV QFCRANSIGG ETVTIDGHEH VPENDEEELL
260 270 280 290 300
KAVAHQPVSV AIDAGSSDFQ LYSEGVFIGE CGTQLNHGVV IVGYGETKNG
310 320 330 340 350
TKYWIVRNSW GPEWGEGGYV RIERGISENE GRCGIAMEAS YPTKLSSTPS
360
THESVVRDDV KDEL
Length:364
Mass (Da):40,971
Last modified:May 1, 2000 - v1
Checksum:i81C725D07DCE2E78
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL049659 Genomic DNA Translation: CAB41163.1
CP002686 Genomic DNA Translation: AEE78406.1
AK119026 mRNA Translation: BAC43602.1
PIRiT06707
RefSeqiNP_566901.1, NM_114696.4
UniGeneiAt.3162

Genome annotation databases

EnsemblPlantsiAT3G48350.1; AT3G48350.1; AT3G48350
GeneIDi823993
GrameneiAT3G48350.1; AT3G48350.1; AT3G48350
KEGGiath:AT3G48350

Similar proteinsi

Entry informationi

Entry nameiCEP3_ARATH
AccessioniPrimary (citable) accession number: Q9STL5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 11, 2011
Last sequence update: May 1, 2000
Last modified: April 25, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health