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Protein

Serpin-Z1C

Gene
N/A
Organism
Triticum aestivum (Wheat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Inhibits chymotrypsin and cathepsin G in vitro.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei357 – 358Reactive bond2

GO - Molecular functioni

Keywordsi

Molecular functionProtease inhibitor, Serine protease inhibitor

Names & Taxonomyi

Protein namesi
Recommended name:
Serpin-Z1C
Alternative name(s):
TriaeZ1c
WSZ1c
OrganismiTriticum aestivum (Wheat)
Taxonomic identifieri4565 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladePooideaeTriticodaeTriticeaeTriticinaeTriticum
Proteomesi
  • UP000019116 Componenti: Unplaced

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Protein family/group databases

Allergomei5724. Tri a 33.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003345701 – 398Serpin-Z1CAdd BLAST398

Proteomic databases

PRIDEiQ9ST58.

Structurei

3D structure databases

ProteinModelPortaliQ9ST58.
SMRiQ9ST58.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni343 – 367RCLAdd BLAST25

Domaini

The reactive center loop (RCL) extends out from the body of the protein and directs binding to the target protease. The protease cleaves the serpin at the reactive site within the RCL, establishing a covalent linkage between the carboxyl group of the serpin reactive site and the serine hydroxyl of the protease. The resulting inactive serpin-protease complex is highly stable (By similarity).By similarity

Sequence similaritiesi

Belongs to the serpin family.Curated

Family and domain databases

InterProiView protein in InterPro
IPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
PANTHERiPTHR11461. PTHR11461. 1 hit.
PfamiView protein in Pfam
PF00079. Serpin. 1 hit.
SMARTiView protein in SMART
SM00093. SERPIN. 1 hit.
SUPFAMiSSF56574. SSF56574. 1 hit.
PROSITEiView protein in PROSITE
PS00284. SERPIN. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9ST58-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATTLATDVR LSIAHQTRFA LRLASTISSN PKSAASNAVF SPVSLHVALS
60 70 80 90 100
LLAAGAGSAT RDQLVATLGT GEVEGLHALA EQVVQFVLAD ASSAGGPHVA
110 120 130 140 150
FANGVFVDAS LPLKPSFQEL AVCKYKADTQ SVDFQTKAAE VATQVNSWVE
160 170 180 190 200
KVTSGRIKDI LPSGSVDNTT KLVLANALYF KGAWTDQFDS SGTKNDYFYL
210 220 230 240 250
PDGSSVQTPF MSSMDDQYLS SSDGLKVLKL PYKQGGDKRQ FSMYILLPEA
260 270 280 290 300
PGGLSNLAEK LSAEPDFLER HIPRQRVALR QFKLPKFKIS FETEASDLLK
310 320 330 340 350
CLGLQLPFSN EADFSEMVDS PMAHGLRVSS VFHQAFVEVN EQGTEAAAST
360 370 380 390
AIKMALLQAR PPSVMDFIAD HPFLFLLRED ISGVVLFMGH VVNPLLSS
Length:398
Mass (Da):42,882
Last modified:May 1, 2000 - v1
Checksum:iFB7B43E5DA3A9019
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ245878 mRNA. Translation: CAB52709.1.
UniGeneiTa.67750.

Genome annotation databases

EnsemblPlantsiTRIAE_CS42_5AL_TGACv1_376818_AA1241160.1; TRIAE_CS42_5AL_TGACv1_376818_AA1241160.1; TRIAE_CS42_5AL_TGACv1_376818_AA1241160.
GrameneiTRIAE_CS42_5AL_TGACv1_376818_AA1241160.1; TRIAE_CS42_5AL_TGACv1_376818_AA1241160.1; TRIAE_CS42_5AL_TGACv1_376818_AA1241160.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ245878 mRNA. Translation: CAB52709.1.
UniGeneiTa.67750.

3D structure databases

ProteinModelPortaliQ9ST58.
SMRiQ9ST58.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei5724. Tri a 33.

Proteomic databases

PRIDEiQ9ST58.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiTRIAE_CS42_5AL_TGACv1_376818_AA1241160.1; TRIAE_CS42_5AL_TGACv1_376818_AA1241160.1; TRIAE_CS42_5AL_TGACv1_376818_AA1241160.
GrameneiTRIAE_CS42_5AL_TGACv1_376818_AA1241160.1; TRIAE_CS42_5AL_TGACv1_376818_AA1241160.1; TRIAE_CS42_5AL_TGACv1_376818_AA1241160.

Family and domain databases

InterProiView protein in InterPro
IPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
PANTHERiPTHR11461. PTHR11461. 1 hit.
PfamiView protein in Pfam
PF00079. Serpin. 1 hit.
SMARTiView protein in SMART
SM00093. SERPIN. 1 hit.
SUPFAMiSSF56574. SSF56574. 1 hit.
PROSITEiView protein in PROSITE
PS00284. SERPIN. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSPZ1C_WHEAT
AccessioniPrimary (citable) accession number: Q9ST58
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 1, 2000
Last modified: May 10, 2017
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.