Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9SSM2

- MDLL_ARATH

UniProt

Q9SSM2 - MDLL_ARATH

Protein

(R)-mandelonitrile lyase-like

Gene

At1g73050

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 84 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    (R)-mandelonitrile = cyanide + benzaldehyde.

    Cofactori

    FAD.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei492 – 4921By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi55 – 8228FADBy similarityAdd
    BLAST

    GO - Molecular functioni

    1. choline dehydrogenase activity Source: InterPro
    2. flavin adenine dinucleotide binding Source: InterPro
    3. mandelonitrile lyase activity Source: UniProtKB-EC

    GO - Biological processi

    1. alcohol metabolic process Source: InterPro

    Keywords - Molecular functioni

    Lyase

    Keywords - Ligandi

    FAD, Flavoprotein

    Enzyme and pathway databases

    BioCyciARA:AT1G73050-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    (R)-mandelonitrile lyase-like (EC:4.1.2.10)
    Alternative name(s):
    Hydroxynitrile lyase-like
    Short name:
    (R)-oxynitrilase-like
    Gene namesi
    Ordered Locus Names:At1g73050
    ORF Names:F3N23.25
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 1

    Organism-specific databases

    TAIRiAT1G73050.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2828Sequence AnalysisAdd
    BLAST
    Chaini29 – 552524(R)-mandelonitrile lyase-likePRO_0000412562Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi44 – 441N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi162 – 1621N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi259 – 2591N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi434 – 4341N-linked (GlcNAc...)Sequence Analysis

    Post-translational modificationi

    Glycosylated.By similarity

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PRIDEiQ9SSM2.

    Expressioni

    Gene expression databases

    GenevestigatoriQ9SSM2.

    Interactioni

    Subunit structurei

    Monomer.By similarity

    Protein-protein interaction databases

    STRINGi3702.AT1G73050.1-P.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9SSM2.
    SMRiQ9SSM2. Positions 38-550.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GMC oxidoreductase family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiCOG2303.
    HOGENOMiHOG000239349.
    InParanoidiQ9SSM2.
    KOiK08248.
    OMAiWVERAIV.
    PhylomeDBiQ9SSM2.

    Family and domain databases

    InterProiIPR012132. GMC_OxRdtase.
    IPR000172. GMC_OxRdtase_N.
    IPR007867. GMC_OxRtase_C.
    [Graphical view]
    PfamiPF05199. GMC_oxred_C. 1 hit.
    PF00732. GMC_oxred_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000137. Alcohol_oxidase. 1 hit.
    PROSITEiPS00623. GMC_OXRED_1. 1 hit.
    PS00624. GMC_OXRED_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q9SSM2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTKRIDSSLL YTALVVLLLL GVVHRSNARP RVNRPPGFMR FISNATDFAS    50
    EDYYDYIIVG GGTAGCPLAA TLSQSFRVLL LERGGVPYNR PNVMSHDGFL 100
    TTLTDVNNFD SPAQSFISEE GVPNARGRVL GGSSAINAGF YSRADKQFFE 150
    NSGLVWDLSS VNQSYEWVER AIVFRPQLRT WQTAIRDALL EVGVHPFNGF 200
    TLEHKVGTKI GGSTFDRTGR RHSSADLLRY ARSSNIRVAV YATVERVLLA 250
    SSPSVSGSNV SAIGVVYRDQ LGRFHHALIR DRGEVILSAG ALGSPQLLFL 300
    SGIGPRSYLS TWGIPVALDQ PHVGDFVYDN PRNGISIVPP VPMENSLIQV 350
    VGVTEDGAFL EAASNVIPFA SPLHSVFIRA PASPLYVPVT TIMEKILGPV 400
    SIGLLRLAST DVRINPVVRF NYFSDPQDLE RCVNGTRKIG EILRSRAMQD 450
    FMIREWFGNR RFRFVGAPLP VDQSNDLVMA DFCRRTVSTI WHYHGGAVVG 500
    KVVDSDLKVI GVNSLRLVDG STFNISPGTN PQATLMMLGR YMGLKMLRER 550
    MR 552
    Length:552
    Mass (Da):60,783
    Last modified:May 1, 2000 - v1
    Checksum:i7747A5D5C2DA7C7A
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti257 – 2571G → R in ABE65766. (PubMed:17147637)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC008017 Genomic DNA. Translation: AAD55652.1.
    CP002684 Genomic DNA. Translation: AEE35408.1.
    DQ446423 mRNA. Translation: ABE65766.1.
    PIRiA96756.
    RefSeqiNP_177448.1. NM_105963.1.
    UniGeneiAt.52489.

    Genome annotation databases

    EnsemblPlantsiAT1G73050.1; AT1G73050.1; AT1G73050.
    GeneIDi843636.
    KEGGiath:AT1G73050.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC008017 Genomic DNA. Translation: AAD55652.1 .
    CP002684 Genomic DNA. Translation: AEE35408.1 .
    DQ446423 mRNA. Translation: ABE65766.1 .
    PIRi A96756.
    RefSeqi NP_177448.1. NM_105963.1.
    UniGenei At.52489.

    3D structure databases

    ProteinModelPortali Q9SSM2.
    SMRi Q9SSM2. Positions 38-550.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 3702.AT1G73050.1-P.

    Proteomic databases

    PRIDEi Q9SSM2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT1G73050.1 ; AT1G73050.1 ; AT1G73050 .
    GeneIDi 843636.
    KEGGi ath:AT1G73050.

    Organism-specific databases

    TAIRi AT1G73050.

    Phylogenomic databases

    eggNOGi COG2303.
    HOGENOMi HOG000239349.
    InParanoidi Q9SSM2.
    KOi K08248.
    OMAi WVERAIV.
    PhylomeDBi Q9SSM2.

    Enzyme and pathway databases

    BioCyci ARA:AT1G73050-MONOMER.

    Miscellaneous databases

    PROi Q9SSM2.

    Gene expression databases

    Genevestigatori Q9SSM2.

    Family and domain databases

    InterProi IPR012132. GMC_OxRdtase.
    IPR000172. GMC_OxRdtase_N.
    IPR007867. GMC_OxRtase_C.
    [Graphical view ]
    Pfami PF05199. GMC_oxred_C. 1 hit.
    PF00732. GMC_oxred_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000137. Alcohol_oxidase. 1 hit.
    PROSITEi PS00623. GMC_OXRED_1. 1 hit.
    PS00624. GMC_OXRED_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
      Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
      , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
      Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations."
      Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.
      Plant Biotechnol. J. 4:317-324(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.

    Entry informationi

    Entry nameiMDLL_ARATH
    AccessioniPrimary (citable) accession number: Q9SSM2
    Secondary accession number(s): Q1PFE0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 21, 2011
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 84 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3