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Protein

Glutathione S-transferase F5

Gene

GSTF5

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.By similarity

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

GO - Molecular functioni

GO - Biological processi

  • glutathione metabolic process Source: GO_Central
  • response to toxic substance Source: UniProtKB-KW
  • toxin catabolic process Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Detoxification

Enzyme and pathway databases

BioCyciARA:AT1G02940-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase F5 (EC:2.5.1.18)
Short name:
AtGSTF5
Alternative name(s):
GST class-phi member 5
Gene namesi
Name:GSTF5
Ordered Locus Names:At1g02940
ORF Names:F22D16.6
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G02940.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: TAIR
  • cytosol Source: UniProtKB-SubCell
  • mitochondrion Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004135431 – 256Glutathione S-transferase F5Add BLAST256

Proteomic databases

PaxDbiQ9SRY6.

Expressioni

Gene expression databases

GenevisibleiQ9SRY6. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G02940.1.

Structurei

3D structure databases

ProteinModelPortaliQ9SRY6.
SMRiQ9SRY6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini37 – 118GST N-terminalAdd BLAST82
Domaini126 – 256GST C-terminalAdd BLAST131

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni47 – 48Glutathione bindingBy similarity2
Regioni76 – 77Glutathione bindingBy similarity2
Regioni89 – 90Glutathione bindingBy similarity2
Regioni102 – 103Glutathione bindingBy similarity2

Sequence similaritiesi

Belongs to the GST superfamily. Phi family.Curated
Contains 1 GST C-terminal domain.Curated
Contains 1 GST N-terminal domain.Curated

Phylogenomic databases

eggNOGiKOG0867. Eukaryota.
COG0625. LUCA.
HOGENOMiHOG000125746.
InParanoidiQ9SRY6.
KOiK00799.
OMAiMWMAIES.
OrthoDBiEOG09360M18.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9SRY6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGINASHVPE TCYHHCNQTF ESSRQCFKWC QELARKDEYK IYGYPYSTNT
60 70 80 90 100
RRVLAVLHEK GLSYDPITVN LIAGDQKKPS FLAINPFGQV PVFLDGGLKL
110 120 130 140 150
TESRAISEYI ATVHKSRGTQ LLNYKSYKTM GTQRMWMAIE SFEFDPLTST
160 170 180 190 200
LTWEQSIKPM YGLKTDYKVV NETEAKLEKV LDIYEERLKN SSFLASNSFT
210 220 230 240 250
MADLYHLPNI QYLMDTHTKR MFVNRPSVRR WVAEITARPA WKRACDVKAW

YHKKKN
Length:256
Mass (Da):29,849
Last modified:October 19, 2011 - v2
Checksum:iCF93E7D6D804C46F
GO

Sequence cautioni

The sequence AAF02872 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009525 Genomic DNA. Translation: AAF02872.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE27499.1.
PIRiH86159.
RefSeqiNP_171793.1. NM_100175.2.

Genome annotation databases

EnsemblPlantsiAT1G02940.1; AT1G02940.1; AT1G02940.
GeneIDi839479.
GrameneiAT1G02940.1; AT1G02940.1; AT1G02940.
KEGGiath:AT1G02940.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009525 Genomic DNA. Translation: AAF02872.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE27499.1.
PIRiH86159.
RefSeqiNP_171793.1. NM_100175.2.

3D structure databases

ProteinModelPortaliQ9SRY6.
SMRiQ9SRY6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT1G02940.1.

Proteomic databases

PaxDbiQ9SRY6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G02940.1; AT1G02940.1; AT1G02940.
GeneIDi839479.
GrameneiAT1G02940.1; AT1G02940.1; AT1G02940.
KEGGiath:AT1G02940.

Organism-specific databases

TAIRiAT1G02940.

Phylogenomic databases

eggNOGiKOG0867. Eukaryota.
COG0625. LUCA.
HOGENOMiHOG000125746.
InParanoidiQ9SRY6.
KOiK00799.
OMAiMWMAIES.
OrthoDBiEOG09360M18.

Enzyme and pathway databases

BioCyciARA:AT1G02940-MONOMER.

Miscellaneous databases

PROiQ9SRY6.

Gene expression databases

GenevisibleiQ9SRY6. AT.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGSTF5_ARATH
AccessioniPrimary (citable) accession number: Q9SRY6
Secondary accession number(s): F4HZ88
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: October 19, 2011
Last modified: November 30, 2016
This is version 101 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.