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Q9SRY6 (GSTF5_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutathione S-transferase F5

Short name=AtGSTF5
EC=2.5.1.18
Alternative name(s):
GST class-phi member 5
Gene names
Name:GSTF5
Ordered Locus Names:At1g02940
ORF Names:F22D16.6
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length256 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides By similarity.

Catalytic activity

RX + glutathione = HX + R-S-glutathione.

Subcellular location

Cytoplasmcytosol Probable.

Sequence similarities

Belongs to the GST superfamily. Phi family.

Contains 1 GST C-terminal domain.

Contains 1 GST N-terminal domain.

Sequence caution

The sequence AAF02872.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
   Biological processDetoxification
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processresponse to toxic substance

Inferred from electronic annotation. Source: UniProtKB-KW

toxin catabolic process

Traceable author statement Ref.3. Source: TAIR

   Cellular_componentcytoplasm

Non-traceable author statement Ref.3. Source: TAIR

cytosol

Inferred from electronic annotation. Source: UniProtKB-SubCell

mitochondrion

Inferred from direct assay PubMed 14671022. Source: TAIR

   Molecular_functionglutathione transferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 256256Glutathione S-transferase F5
PRO_0000413543

Regions

Domain37 – 11882GST N-terminal
Domain126 – 256131GST C-terminal
Region47 – 482Glutathione binding By similarity
Region76 – 772Glutathione binding By similarity
Region89 – 902Glutathione binding By similarity
Region102 – 1032Glutathione binding By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9SRY6 [UniParc].

Last modified October 19, 2011. Version 2.
Checksum: CF93E7D6D804C46F

FASTA25629,849
        10         20         30         40         50         60 
MGINASHVPE TCYHHCNQTF ESSRQCFKWC QELARKDEYK IYGYPYSTNT RRVLAVLHEK 

        70         80         90        100        110        120 
GLSYDPITVN LIAGDQKKPS FLAINPFGQV PVFLDGGLKL TESRAISEYI ATVHKSRGTQ 

       130        140        150        160        170        180 
LLNYKSYKTM GTQRMWMAIE SFEFDPLTST LTWEQSIKPM YGLKTDYKVV NETEAKLEKV 

       190        200        210        220        230        240 
LDIYEERLKN SSFLASNSFT MADLYHLPNI QYLMDTHTKR MFVNRPSVRR WVAEITARPA 

       250 
WKRACDVKAW YHKKKN 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Probing the diversity of the Arabidopsis glutathione S-transferase gene family."
Wagner U., Edwards R., Dixon D.P., Mauch F.
Plant Mol. Biol. 49:515-532(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC009525 Genomic DNA. Translation: AAF02872.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE27499.1.
PIRH86159.
RefSeqNP_171793.1. NM_100175.1.
UniGeneAt.51463.

3D structure databases

ProteinModelPortalQ9SRY6.
SMRQ9SRY6. Positions 40-243.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT1G02940.1-P.

Proteomic databases

PaxDbQ9SRY6.
PRIDEQ9SRY6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G02940.1; AT1G02940.1; AT1G02940.
GeneID839479.
KEGGath:AT1G02940.

Organism-specific databases

TAIRAT1G02940.

Phylogenomic databases

eggNOGCOG0625.
HOGENOMHOG000125746.
InParanoidQ9SRY6.
KOK00799.
OMAMWMAIES.

Enzyme and pathway databases

BioCycARA:AT1G02940-MONOMER.

Gene expression databases

GenevestigatorQ9SRY6.

Family and domain databases

Gene3D1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamPF00043. GST_C. 1 hit.
PF13417. GST_N_3. 1 hit.
[Graphical view]
SUPFAMSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGSTF5_ARATH
AccessionPrimary (citable) accession number: Q9SRY6
Secondary accession number(s): F4HZ88
Entry history
Integrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: October 19, 2011
Last modified: May 14, 2014
This is version 88 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names