Q9SRV5 (Q9SRV5_ARATH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Cobalamin-independent methionine synthase EMBL CAE55864.1
EC=2.1.1.14 EMBL CAE55864.1

Submitted name:
Methionine synthase 2 EMBL AEE73989.1
Submitted name:
Putative methionine synthase EMBL AAF00639.1

Gene names

Name:	F20H23.19 EMBL AAF00639.1
Synonyms:	atms2 EMBL CAE55864.1, MS2 EMBL AEE73989.1
Ordered Locus Names:	At3g03780 TAIR At3g03780
ORF Names:	AT3G03780 EMBL AEE73989.1

Organism

Arabidopsis thaliana (Mouse-ear cress) EMBL AAF00639.1

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	765 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Molecular function	Methyltransferase EMBL CAE55864.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	response to cadmium ion Inferred from expression pattern. Source: TAIR response to salt stress Inferred from expression pattern. Source: TAIR
Cellular component	apoplast Inferred from direct assay. Source: TAIR chloroplast envelope Inferred from direct assay. Source: TAIR cytosol Inferred from direct assay Ref.1. Source: TAIR plasma membrane Inferred from direct assay. Source: TAIR plasmodesma Inferred from direct assay. Source: TAIR
Molecular function	5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity Inferred from electronic annotation. Source: EC methionine synthase activity Inferred from direct assay Ref.1. Source: TAIR zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9SRV5 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: EB478D815910E701	FASTA	765	84,584
	10 20 30 40 50 60 MASHIVGYPR MGPKRELKFA LESFWDGKSS ADDLQKVSAD LRSDIWKQMS AAGIKYIPSN 70 80 90 100 110 120 TFSHYDQVLD TTAMLGAVPS RYGFTSGEIG LDVYFSMARG NASVPAMEMT KWFDTNYHYI 130 140 150 160 170 180 VPELGPEVKF SYASHKAVNE YKEAKALGVE TVPVLVGPVS YLLLSKLAKG VDKSFDLLSL 190 200 210 220 230 240 LPKILPVYKE VIAELKAAGA SWIQLDEPLF VMDLEGHKLQ AFSGAYAELE STLSGLNVLV 250 260 270 280 290 300 ETYFADIPAE AYKTLTSLKG VTAFGFDLVR GTKTIDLIKS GFPQGKYLFA GVVDGRNIWA 310 320 330 340 350 360 NDLAASLITL QSLEGVVGKD KLVVSTSCSL LHTAVDLINE TKLDAEIKSW LAFAAQKVVE 370 380 390 400 410 420 VDALAKALAG QTNESFFTAN ADALSSRRSS PRVTNESVQK AAAALKGSDH RRTTEVSARL 430 440 450 460 470 480 DAQQKKLNLP ILPTTTIGSF PQTVELRRVR REYKAKKISE EDYVKAIKEE IKKVVDIQED 490 500 510 520 530 540 LDIDVLVHGE PERNDMVEYF GEQLSGFAFT ANGWVQSYGS RCVKPPVIYG DVSRPKPMTV 550 560 570 580 590 600 FWSSTAQSMT KRPMKGMLTG PVTILNWSFV RNDQPRHETC YQIALAIKDE VEDLEKGGIG 610 620 630 640 650 660 VIQIDEAALR EGLPLRKAEH SFYLDWAVHS FRITNCGVQD STQIHTHMCY SNFNDIIHSI 670 680 690 700 710 720 IDMDADVITI ENSRSDEKLL SVFREGVKYG AGIGPGVYDI HSPRIPSTDE IADRINKMLA 730 740 750 760 VLEQNILWVN PDCGLKTRKY TEVKPALKAM VDAAKLIRSQ LGSAK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Methionine metabolism in plants: chloroplasts are autonomous for de novo methionine synthesis and can import S-adenosylmethionine from the cytosol." Ravanel S., Block M.A., Rippert P., Jabrin S., Curien G., Rebeille F., Douce R. J. Biol. Chem. 279:22548-22557(2004) [PubMed: 15024005] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana." European Union Chromosome 3 Arabidopsis Sequencing Consortium, Institute for Genomic Research, Kazusa DNA Research Institute Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F. , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. Nature 408:820-822(2000) [PubMed: 11130713] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[3]	"Full-length messenger RNA sequences greatly improve genome annotation." Haas B.J., Volfovsky N., Town C.D., Troukhan M., Alexandrov N., Feldmann K.A., Flavell R.B., White O., Salzberg S.L. Genome Biol. 3:RESEARCH0029-RESEARCH0029(2002) [PubMed: 12093376] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[4]	"Features of Arabidopsis genes and genome discovered using full-length cDNAs." Alexandrov N.A., Troukhan M.E., Brover V.V., Flavell R.B., Feldmann K.A. Plant Mol. Biol. 60:71-87(2006) Cited for: NUCLEOTIDE SEQUENCE.
[5]	"Arabidopsis Open Reading Frame (ORF) Clones." Yamada K., Chan M.M., Chang C.H., Dale J.M., Hsuan V.W., Lee J.M., Quach H.L., Tang C.C., Toriumi M., Wallender E.K., Wong C., Wu H.C., Yu G., Yuan S., Chen H., Cheuk R., Jones T., Kim C.J. , Nguyen M., Palm C.J., Shinn P., Southwick A., Tripp M.G., Wu T., Davis R.W., Ecker J.R., Theologis A. Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[6]	Arabidopsis TAIR10 Release Swarbreck D., Lamesch P., Wilks C., Huala E. Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[7]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[8]	Brover V., Troukhan M., Alexandrov N., Lu Y.-P., Flavell R., Feldmann K. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[9]	"Arabidopsis thaliana chromosome III BAC F20H23 genomic sequence." Lin X., Kaul S., Town C.D., Benito M.-I., Creasy T.H., Haas B., Ronning C.M., Koo H., Fujii C.Y., Utterback T.R., Barnstead M.E., Bowman C.L., White O., Nierman W.C., Fraser C.M. Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC009540 Genomic DNA. Translation: AAF00639.1. AY084559 mRNA. Translation: AAM61126.1. AY150385 mRNA. Translation: AAN12930.1. CP002686 Genomic DNA. Translation: AEE73989.1. CP002686 Genomic DNA. Translation: AEE73990.1. CP002686 Genomic DNA. Translation: AEE73991.1. AJ608674 mRNA. Translation: CAE55864.1.
IPI	IPI00532889.
RefSeq	NP_001118564.1. NM_001125092.1. NP_187028.1. NM_111249.4. NP_850507.1. NM_180176.3.
UniGene	At.18359.
3D structure databases
ProteinModelPortal	Q9SRV5.
SMR	Q9SRV5. Positions 2-760.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9SRV5.
Proteomic databases
PRIDE	Q9SRV5.
ProMEX	Q9SRV5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT3G03780.1; AT3G03780.1; AT3G03780. AT3G03780.2; AT3G03780.2; AT3G03780. AT3G03780.3; AT3G03780.3; AT3G03780.
GeneID	821147.
KEGG	ath:AT3G03780.
NMPDR	fig|3702.1.peg.12333.
Organism-specific databases
TAIR	At3g03780.
Phylogenomic databases
GeneTree	EPGT00050000016428.
InParanoid	Q9SRV5.
OMA	MLDTAVM.
PhylomeDB	Q9SRV5.
ProtClustDB	PLN02475.
Gene expression databases
Genevestigator	Q9SRV5.
Family and domain databases
HAMAP	MF_00172. Meth_synth. [Tree]
InterPro	IPR013215. Cbl-indep_Met_Synth_N. IPR006276. Cobalamin-indep_Met_synthase. IPR002629. Methionine_synth. [Graphical view]
KO	K00549.
Pfam	PF08267. Meth_synt_1. 1 hit. PF01717. Meth_synt_2. 1 hit. [Graphical view]
PIRSF	PIRSF000382. MeTrfase_B12_ind. 1 hit.
TIGRFAMs	TIGR01371. Met_syn_B12ind. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q9SRV5_ARATH

Accession

Primary (citable) accession number: Q9SRV5

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	January 25, 2012
This is version 90 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)