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Q9SRH6 (HIR3_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Hypersensitive-induced response protein 3

Short name=AtHIR3
Gene names
Name:HIR3
Synonyms:P31
Ordered Locus Names:At3g01290
ORF Names:T22N4.8, T4P13.3
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length285 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

Self-interacts and forms heteromers. Interacts with NB-LRR class of R proteins before R proteins (e.g. RPS2 or RPM1) are activated by the effectors. Ref.9

Subcellular location

Cell membrane; Lipid-anchor Potential; Cytoplasmic side Probable Ref.5 Ref.6 Ref.7 Ref.8 Ref.9.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed Potential
Chain2 – 285284Hypersensitive-induced response protein 3
PRO_0000398598

Regions

Coiled coil113 – 13927 Potential
Coiled coil165 – 18521 Potential

Amino acid modifications

Lipidation21N-myristoyl glycine Potential

Sequences

Sequence LengthMass (Da)Tools
Q9SRH6 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 57A46F2A29CFB74C

FASTA28531,321
        10         20         30         40         50         60 
MGNLFCCVLV KQSDVAVKER FGKFQKVLNP GLQFVPWVIG DYVAGTLTLR LQQLDVQCET 

        70         80         90        100        110        120 
KTKDNVFVTV VASIQYRVLA DKASDAFYRL SNPTTQIKAY VFDVIRACVP KLNLDDVFEQ 

       130        140        150        160        170        180 
KNEIAKSVEE ELDKAMTAYG YEILQTLIID IEPDQQVKRA MNEINAAARM RVAASEKAEA 

       190        200        210        220        230        240 
EKIIQIKRAE GEAESKYLSG LGIARQRQAI VDGLRDSVLG FAGNVPGTSA KDVLDMVMMT 

       250        260        270        280 
QYFDTMRDIG ATSKSSAVFI PHGPGAVSDV AAQIRNGLLQ ANNAS 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana."
Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F. expand/collapse author list , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
Nature 408:820-822(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Arabidopsis ORF clones."
Shinn P., Chen H., Kim C.J., Ecker J.R.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Full-length cDNA from Arabidopsis thaliana."
Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[5]"Identification of new intrinsic proteins in Arabidopsis plasma membrane proteome."
Marmagne A., Rouet M.-A., Ferro M., Rolland N., Alcon C., Joyard J., Garin J., Barbier-Brygoo H., Ephritikhine G.
Mol. Cell. Proteomics 3:675-691(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY, SUBCELLULAR LOCATION.
[6]"Arabidopsis plasma membrane proteomics identifies components of transport, signal transduction and membrane trafficking."
Alexandersson E., Saalbach G., Larsson C., Kjellbom P.
Plant Cell Physiol. 45:1543-1556(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
Strain: cv. Columbia.
Tissue: Leaf and Petiole.
[7]"Mapping the Arabidopsis organelle proteome."
Dunkley T.P.J., Hester S., Shadforth I.P., Runions J., Weimar T., Hanton S.L., Griffin J.L., Bessant C., Brandizzi F., Hawes C., Watson R.B., Dupree P., Lilley K.S.
Proc. Natl. Acad. Sci. U.S.A. 103:6518-6523(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[8]"A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome."
Marmagne A., Ferro M., Meinnel T., Bruley C., Kuhn L., Garin J., Barbier-Brygoo H., Ephritikhine G.
Mol. Cell. Proteomics 6:1980-1996(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[9]"New classes of proteins forming complexes with resistance proteins."
Qi Y., Katagiri F.
(In) Proceedings of the 20th international conference on Arabidopsis research, abstract#501734213, Edinburgh (2009)
Cited for: INTERACTION WITH RESISTANCE PROTEINS, SUBUNIT, SUBCELLULAR LOCATION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC008261 Genomic DNA. Translation: AAF26146.1.
AC010676 Genomic DNA. Translation: AAF03497.1.
CP002686 Genomic DNA. Translation: AEE73633.1.
BT024707 mRNA. Translation: ABD59045.1.
AY084426 mRNA. Translation: AAM61000.1.
RefSeqNP_566135.1. NM_110995.2.
UniGeneAt.43760.

3D structure databases

ProteinModelPortalQ9SRH6.
SMRQ9SRH6. Positions 41-181.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid6642. 1 interaction.
IntActQ9SRH6. 6 interactions.
STRING3702.AT3G01290.1-P.

Proteomic databases

PaxDbQ9SRH6.
PRIDEQ9SRH6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT3G01290.1; AT3G01290.1; AT3G01290.
GeneID821309.
KEGGath:AT3G01290.

Organism-specific databases

TAIRAT3G01290.

Phylogenomic databases

eggNOGCOG0330.
HOGENOMHOG000035168.
InParanoidQ9SRH6.
OMADIEPDEK.
PhylomeDBQ9SRH6.
ProtClustDBCLSN2682581.

Gene expression databases

GenevestigatorQ9SRH6.

Family and domain databases

InterProIPR001107. Band_7.
IPR028512. HIR.
IPR001972. Stomatin_fam.
[Graphical view]
PANTHERPTHR10264. PTHR10264. 1 hit.
PTHR10264:SF25. PTHR10264:SF25. 1 hit.
PfamPF01145. Band_7. 1 hit.
[Graphical view]
SMARTSM00244. PHB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHIR3_ARATH
AccessionPrimary (citable) accession number: Q9SRH6
Entry history
Integrated into UniProtKB/Swiss-Prot: October 5, 2010
Last sequence update: May 1, 2000
Last modified: April 16, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names