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Q9SR24 (P2C36_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable protein phosphatase 2C 36

Short name=AtPP2C36
EC=3.1.3.16
Alternative name(s):
Protein POLTERGEIST-LIKE 3
Protein phosphatase 2C PLL3
Short name=PP2C PLL3
Gene names
Name:PLL3
Ordered Locus Names:At3g09400
ORF Names:F3L24.29
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length650 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity.

Subcellular location

Nucleus Potential.

Domain

The conserved PP2C phosphatase domain (240-639) is interrupted by an insertion of approximately 100 amino acids.

Disruption phenotype

No visible phenotype. Ref.3

Sequence similarities

Belongs to the PP2C family.

Contains 1 PP2C-like domain.

Ontologies

Keywords
   Cellular componentNucleus
   Coding sequence diversityAlternative splicing
   LigandMagnesium
Manganese
Metal-binding
   Molecular functionHydrolase
Protein phosphatase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoprotein phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Alternative products

This entry describes 1 isoform produced by alternative splicing. [Select]

Note: A number of isoforms are produced. According to EST sequences.
Isoform 1 (identifier: Q9SR24-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 650650Probable protein phosphatase 2C 36
PRO_0000301261

Regions

Domain305 – 613309PP2C-like
Compositional bias67 – 704Poly-Thr
Compositional bias148 – 19548Lys-rich

Sites

Metal binding2761Manganese 1 By similarity
Metal binding2761Manganese 2 By similarity
Metal binding2771Manganese 1; via carbonyl oxygen By similarity
Metal binding5691Manganese 2 By similarity
Metal binding6321Manganese 2 By similarity

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 54B6EBB6A4264106

FASTA65072,381
        10         20         30         40         50         60 
MGNGVASFSG CCAGTTAGEI SGRYVTGVGL VQENLGHSFC YVRPVLTGSK SSFPPEPPLR 

        70         80         90        100        110        120 
PDPIPGTTTT FRSISGASVS ANTSTALSTS LSTDTSGIAS AFESSNRFAS LPLQPVPRSP 

       130        140        150        160        170        180 
IKKSDHGSGL FERRFLSGPI ESGLVSGKKT KEKAKLKKSG SKSFTKPKLK KSESKIFTFK 

       190        200        210        220        230        240 
NVFTNLSCSK KSVIKPINGF DSFDGSSDTD RYIPEINSLS TIVSSHEKPR IKEEEDKTES 

       250        260        270        280        290        300 
ALEEPKIQWA QGKAGEDRVH VILSEENGWL FVGIYDGFSG PDPPDYLIKN LYTAVLRELK 

       310        320        330        340        350        360 
GLLWIDKGES YNRNGESNIE KQSTVEHASD SDQENCPVMN GNDVACGSRN ITSDVKKLQW 

       370        380        390        400        410        420 
RCEWEHNSSN KSNNINHKDV LRALQQALEK TEESFDLMVN ENPELALMGS CVLVTLMKGE 

       430        440        450        460        470        480 
DVYVMSVGDS RAVLARRPNV EKMKMQKELE RVKEESPLET LFITERGLSL LVPVQLNKEH 

       490        500        510        520        530        540 
STSVEEEVRR IKKEHPDDIL AIENNRVKGY LKVTRAFGAG FLKQPKWNEA LLEMFRIDYV 

       550        560        570        580        590        600 
GTSPYITCSP SLHHHRLSSR DKFLILSSDG LYEYFSNEEA IFEVDSFISA FPEGDPAQHL 

       610        620        630        640        650 
IQEVLLRAAK KYGMDFHELL EIPQGDRRRY HDDVSVIVIS LEGRIWRSSM 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana."
Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F. expand/collapse author list , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
Nature 408:820-822(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"POL and related phosphatases are dosage-sensitive regulators of meristem and organ development in Arabidopsis."
Song S.-K., Clark S.E.
Dev. Biol. 285:272-284(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE, DISRUPTION PHENOTYPE.
[4]"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC011436 Genomic DNA. Translation: AAF14035.1.
CP002686 Genomic DNA. Translation: AEE74761.1.
RefSeqNP_187551.1. NM_111774.1.
UniGeneAt.53233.

3D structure databases

ProteinModelPortalQ9SR24.
SMRQ9SR24. Positions 405-645.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT3G09400.1-P.

Proteomic databases

PRIDEQ9SR24.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT3G09400.1; AT3G09400.1; AT3G09400. [Q9SR24-1]
GeneID820099.
KEGGath:AT3G09400.

Organism-specific databases

TAIRAT3G09400.

Phylogenomic databases

eggNOGCOG0631.
HOGENOMHOG000239375.
InParanoidQ9SR24.
OMANEEAIFE.
PhylomeDBQ9SR24.
ProtClustDBCLSN2685134.

Enzyme and pathway databases

BioCycARA:AT3G09400-MONOMER.
ARA:GQT-422-MONOMER.

Gene expression databases

GenevestigatorQ9SR24.

Family and domain databases

Gene3D3.60.40.10. 3 hits.
InterProIPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERPTHR13832. PTHR13832. 1 hit.
PfamPF00481. PP2C. 1 hit.
[Graphical view]
SMARTSM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMSSF81606. SSF81606. 3 hits.
ProtoNetSearch...

Entry information

Entry nameP2C36_ARATH
AccessionPrimary (citable) accession number: Q9SR24
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: May 1, 2000
Last modified: April 16, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names