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Q9SR24

- P2C36_ARATH

UniProt

Q9SR24 - P2C36_ARATH

Protein

Probable protein phosphatase 2C 36

Gene

PLL3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 82 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi276 – 2761Manganese 1By similarity
    Metal bindingi276 – 2761Manganese 2By similarity
    Metal bindingi277 – 2771Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi569 – 5691Manganese 2By similarity
    Metal bindingi632 – 6321Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. phosphoprotein phosphatase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Enzyme and pathway databases

    BioCyciARA:AT3G09400-MONOMER.
    ARA:GQT-422-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable protein phosphatase 2C 36 (EC:3.1.3.16)
    Short name:
    AtPP2C36
    Alternative name(s):
    Protein POLTERGEIST-LIKE 3
    Protein phosphatase 2C PLL3
    Short name:
    PP2C PLL3
    Gene namesi
    Name:PLL3
    Ordered Locus Names:At3g09400
    ORF Names:F3L24.29
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 3

    Organism-specific databases

    TAIRiAT3G09400.

    Subcellular locationi

    Nucleus Curated

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    Pathology & Biotechi

    Disruption phenotypei

    No visible phenotype.1 Publication

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 650650Probable protein phosphatase 2C 36PRO_0000301261Add
    BLAST

    Proteomic databases

    PRIDEiQ9SR24.

    Expressioni

    Gene expression databases

    GenevestigatoriQ9SR24.

    Interactioni

    Protein-protein interaction databases

    STRINGi3702.AT3G09400.1-P.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9SR24.
    SMRiQ9SR24. Positions 405-645.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini305 – 613309PP2C-likeAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi67 – 704Poly-Thr
    Compositional biasi148 – 19548Lys-richAdd
    BLAST

    Domaini

    The conserved PP2C phosphatase domain (240-639) is interrupted by an insertion of approximately 100 amino acids.

    Sequence similaritiesi

    Belongs to the PP2C family.Curated
    Contains 1 PP2C-like domain.Curated

    Phylogenomic databases

    eggNOGiCOG0631.
    HOGENOMiHOG000239375.
    InParanoidiQ9SR24.
    OMAiNEEAIFE.
    PhylomeDBiQ9SR24.

    Family and domain databases

    Gene3Di3.60.40.10. 3 hits.
    InterProiIPR001932. PP2C-like_dom.
    IPR015655. Protein_Pase_2C.
    [Graphical view]
    PANTHERiPTHR13832. PTHR13832. 1 hit.
    PfamiPF00481. PP2C. 1 hit.
    [Graphical view]
    SMARTiSM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 3 hits.

    Sequencei

    Sequence statusi: Complete.

    This entry describes 1 isoform i produced by alternative splicing. Align

    Note: A number of isoforms are produced. According to EST sequences.

    Isoform 1 (identifier: Q9SR24-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MGNGVASFSG CCAGTTAGEI SGRYVTGVGL VQENLGHSFC YVRPVLTGSK    50
    SSFPPEPPLR PDPIPGTTTT FRSISGASVS ANTSTALSTS LSTDTSGIAS 100
    AFESSNRFAS LPLQPVPRSP IKKSDHGSGL FERRFLSGPI ESGLVSGKKT 150
    KEKAKLKKSG SKSFTKPKLK KSESKIFTFK NVFTNLSCSK KSVIKPINGF 200
    DSFDGSSDTD RYIPEINSLS TIVSSHEKPR IKEEEDKTES ALEEPKIQWA 250
    QGKAGEDRVH VILSEENGWL FVGIYDGFSG PDPPDYLIKN LYTAVLRELK 300
    GLLWIDKGES YNRNGESNIE KQSTVEHASD SDQENCPVMN GNDVACGSRN 350
    ITSDVKKLQW RCEWEHNSSN KSNNINHKDV LRALQQALEK TEESFDLMVN 400
    ENPELALMGS CVLVTLMKGE DVYVMSVGDS RAVLARRPNV EKMKMQKELE 450
    RVKEESPLET LFITERGLSL LVPVQLNKEH STSVEEEVRR IKKEHPDDIL 500
    AIENNRVKGY LKVTRAFGAG FLKQPKWNEA LLEMFRIDYV GTSPYITCSP 550
    SLHHHRLSSR DKFLILSSDG LYEYFSNEEA IFEVDSFISA FPEGDPAQHL 600
    IQEVLLRAAK KYGMDFHELL EIPQGDRRRY HDDVSVIVIS LEGRIWRSSM 650
    Length:650
    Mass (Da):72,381
    Last modified:May 1, 2000 - v1
    Checksum:i54B6EBB6A4264106
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC011436 Genomic DNA. Translation: AAF14035.1.
    CP002686 Genomic DNA. Translation: AEE74761.1.
    RefSeqiNP_187551.1. NM_111774.1. [Q9SR24-1]
    UniGeneiAt.53233.

    Genome annotation databases

    EnsemblPlantsiAT3G09400.1; AT3G09400.1; AT3G09400. [Q9SR24-1]
    GeneIDi820099.
    KEGGiath:AT3G09400.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC011436 Genomic DNA. Translation: AAF14035.1 .
    CP002686 Genomic DNA. Translation: AEE74761.1 .
    RefSeqi NP_187551.1. NM_111774.1. [Q9SR24-1 ]
    UniGenei At.53233.

    3D structure databases

    ProteinModelPortali Q9SR24.
    SMRi Q9SR24. Positions 405-645.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 3702.AT3G09400.1-P.

    Proteomic databases

    PRIDEi Q9SR24.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT3G09400.1 ; AT3G09400.1 ; AT3G09400 . [Q9SR24-1 ]
    GeneIDi 820099.
    KEGGi ath:AT3G09400.

    Organism-specific databases

    TAIRi AT3G09400.

    Phylogenomic databases

    eggNOGi COG0631.
    HOGENOMi HOG000239375.
    InParanoidi Q9SR24.
    OMAi NEEAIFE.
    PhylomeDBi Q9SR24.

    Enzyme and pathway databases

    BioCyci ARA:AT3G09400-MONOMER.
    ARA:GQT-422-MONOMER.

    Gene expression databases

    Genevestigatori Q9SR24.

    Family and domain databases

    Gene3Di 3.60.40.10. 3 hits.
    InterProi IPR001932. PP2C-like_dom.
    IPR015655. Protein_Pase_2C.
    [Graphical view ]
    PANTHERi PTHR13832. PTHR13832. 1 hit.
    Pfami PF00481. PP2C. 1 hit.
    [Graphical view ]
    SMARTi SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 3 hits.
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana."
      Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F.
      , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
      Nature 408:820-822(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "POL and related phosphatases are dosage-sensitive regulators of meristem and organ development in Arabidopsis."
      Song S.-K., Clark S.E.
      Dev. Biol. 285:272-284(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE, DISRUPTION PHENOTYPE.
    4. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
      Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
      BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiP2C36_ARATH
    AccessioniPrimary (citable) accession number: Q9SR24
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 11, 2007
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 82 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3