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Q9SQR3

- D14_ARATH

UniProt

Q9SQR3 - D14_ARATH

Protein

Probable strigolactone esterase D14 homolog

Gene

D14

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 82 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
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    Functioni

    Involved in strigolactone signaling pathway. May function downstream of strigolactone synthesis, as a component of hormone signaling or as an enzyme that participates in the conversion of strigolactones to the bioactive form. Strigolactones are hormones that inhibit tillering and shoot branching through the MAX-dependent pathway, contribute to the regulation of shoot architectural response to phosphate-limiting conditions and function as rhizosphere signal that stimulates hyphal branching of arbuscular mycorrhizal fungi and trigger seed germination of root parasitic weeds.1 Publication

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei97 – 971NucleophileBy similarity
    Active sitei218 – 2181By similarity
    Active sitei247 – 2471By similarity

    GO - Molecular functioni

    1. hydrolase activity Source: UniProtKB-KW

    GO - Biological processi

    1. secondary shoot formation Source: UniProtKB
    2. strigolactone biosynthetic process Source: UniProtKB

    Keywords - Molecular functioni

    Hydrolase

    Protein family/group databases

    MEROPSiS33.A18.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable strigolactone esterase D14 homolog
    Alternative name(s):
    Protein DWARF-14
    Short name:
    AtD14
    Gene namesi
    Name:D14
    Ordered Locus Names:At3g03990
    ORF Names:T11I18.10
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 3

    Organism-specific databases

    TAIRiAT3G03990.

    Pathology & Biotechi

    Disruption phenotypei

    Increased shoot branching.1 Publication

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 267267Probable strigolactone esterase D14 homologPRO_0000422053Add
    BLAST

    Proteomic databases

    PRIDEiQ9SQR3.

    Expressioni

    Gene expression databases

    ArrayExpressiQ9SQR3.
    GenevestigatoriQ9SQR3.

    Interactioni

    Protein-protein interaction databases

    STRINGi3702.AT3G03990.1-P.

    Structurei

    Secondary structure

    1
    267
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Turni7 – 115
    Beta strandi14 – 163
    Beta strandi21 – 255
    Helixi32 – 387
    Helixi40 – 434
    Beta strandi46 – 516
    Beta strandi54 – 563
    Helixi61 – 633
    Turni66 – 683
    Beta strandi70 – 734
    Helixi74 – 8512
    Beta strandi94 – 963
    Helixi98 – 10912
    Beta strandi111 – 1133
    Beta strandi118 – 1214
    Helixi138 – 15013
    Helixi152 – 16413
    Helixi170 – 18112
    Helixi184 – 19512
    Helixi202 – 2054
    Beta strandi211 – 2144
    Beta strandi219 – 2213
    Helixi225 – 2317
    Helixi249 – 2524
    Helixi254 – 2629

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4IH4X-ray3.50A/B/C/D1-267[»]
    ProteinModelPortaliQ9SQR3.
    SMRiQ9SQR3. Positions 6-266.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the AB hydrolase superfamily.Curated

    Phylogenomic databases

    InParanoidiQ9SQR3.
    OMAiTTLDPYV.
    PhylomeDBiQ9SQR3.

    Family and domain databases

    Gene3Di3.40.50.1820. 1 hit.
    InterProiIPR029058. AB_hydrolase.
    [Graphical view]
    SUPFAMiSSF53474. SSF53474. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q9SQR3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSQHNILEAL NVRVVGTGDR ILFLAHGFGT DQSAWHLILP YFTQNYRVVL    50
    YDLVCAGSVN PDYFDFNRYT TLDPYVDDLL NIVDSLGIQN CAYVGHSVSA 100
    MIGIIASIRR PELFSKLILI GFSPRFLNDE DYHGGFEEGE IEKVFSAMEA 150
    NYEAWVHGFA PLAVGADVPA AVREFSRTLF NMRPDISLFV SRTVFNSDLR 200
    GVLGLVRVPT CVIQTAKDVS VPASVAEYLR SHLGGDTTVE TLKTEGHLPQ 250
    LSAPAQLAQF LRRALPR 267
    Length:267
    Mass (Da):29,625
    Last modified:May 1, 2000 - v1
    Checksum:i47E326EEE2AE5204
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti236 – 2361D → E in AAM65892. 1 PublicationCurated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC011698 Genomic DNA. Translation: AAF05858.1.
    CP002686 Genomic DNA. Translation: AEE74023.1.
    AY064145 mRNA. Translation: AAL36052.1.
    AY097402 mRNA. Translation: AAM19918.1.
    AY088353 mRNA. Translation: AAM65892.1.
    RefSeqiNP_566220.1. NM_111270.2.
    UniGeneiAt.27069.

    Genome annotation databases

    EnsemblPlantsiAT3G03990.1; AT3G03990.1; AT3G03990.
    GeneIDi819554.
    KEGGiath:AT3G03990.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC011698 Genomic DNA. Translation: AAF05858.1 .
    CP002686 Genomic DNA. Translation: AEE74023.1 .
    AY064145 mRNA. Translation: AAL36052.1 .
    AY097402 mRNA. Translation: AAM19918.1 .
    AY088353 mRNA. Translation: AAM65892.1 .
    RefSeqi NP_566220.1. NM_111270.2.
    UniGenei At.27069.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4IH4 X-ray 3.50 A/B/C/D 1-267 [» ]
    ProteinModelPortali Q9SQR3.
    SMRi Q9SQR3. Positions 6-266.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 3702.AT3G03990.1-P.

    Protein family/group databases

    MEROPSi S33.A18.

    Proteomic databases

    PRIDEi Q9SQR3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT3G03990.1 ; AT3G03990.1 ; AT3G03990 .
    GeneIDi 819554.
    KEGGi ath:AT3G03990.

    Organism-specific databases

    TAIRi AT3G03990.

    Phylogenomic databases

    InParanoidi Q9SQR3.
    OMAi TTLDPYV.
    PhylomeDBi Q9SQR3.

    Gene expression databases

    ArrayExpressi Q9SQR3.
    Genevestigatori Q9SQR3.

    Family and domain databases

    Gene3Di 3.40.50.1820. 1 hit.
    InterProi IPR029058. AB_hydrolase.
    [Graphical view ]
    SUPFAMi SSF53474. SSF53474. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana."
      Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F.
      , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
      Nature 408:820-822(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    4. "Full-length cDNA from Arabidopsis thaliana."
      Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
      Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    5. "Specialisation within the DWARF14 protein family confers distinct responses to karrikins and strigolactones in Arabidopsis."
      Waters M.T., Nelson D.C., Scaffidi A., Flematti G.R., Sun Y.K., Dixon K.W., Smith S.M.
      Development 139:1285-1295(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, DISRUPTION PHENOTYPE.
      Strain: cv. Columbia.

    Entry informationi

    Entry nameiD14_ARATH
    AccessioniPrimary (citable) accession number: Q9SQR3
    Secondary accession number(s): Q8L9M4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 3, 2013
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 82 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3