Reviewed,
UniProtKB/Swiss-Prot Q9SQI2 (GIGAN_ARATH)
Last modified
June 16, 2009.
Version 57.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Protein GIGANTEA | ||||||
| Gene names |
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| Organism | Arabidopsis thaliana (Mouse-ear cress) [Complete proteome] | ||||||
| Taxonomic identifier | 3702 [NCBI] | ||||||
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis |
Protein attributes
| Sequence length | 1173 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | Involved in regulation of circadian rhythm and photoperiodic flowering. May play a role in maintenance of circadian amplitude and period length. Is involved in phytochrome B signaling. Regulates 'CONSTANS' in the long-day flowering pathway. Ref.5 |
| Subunit structure | Interacts with SPY. Ref.6 |
| Subcellular location | |
| Tissue specificity | Widely expressed with highest levels in inflorescence apices, young flowers and young siliques. |
| Developmental stage | Found at all stages. |
| Induction | Expressed with a circadian rhythm with the highest level 10 hours into the light and the lowest level at dawn. The peak of expression in long days is slightly lower, shifted later and the decrease is slower. |
| Sequence similarities | Belongs to the GIGANTEA family. |
| Sequence caution | The sequence AAC25507.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence AAF00023.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAA72908.1 differs from that shown. Reason: Erroneous gene model prediction. |
Ontologies
Binary interactions
With | Entry | #Exp. | IntAct | Notes |
|---|---|---|---|---|
| ADO1 | Q94BT6 | 4 | EBI-446380,EBI-300691 | |
| ADO2 | Q8W420 | 2 | EBI-446380,EBI-1015688 | |
| ADO3 | Q9C9W9 | 10 | EBI-446380,EBI-401228 | |
| DOF5.5 | Q8W1E3 | 2 | EBI-446380,EBI-1536051 | |
| SPY | Q96301 | 1 | EBI-446380,EBI-446372 |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 1173 | 1173 | Protein GIGANTEA | PRO_0000087489 | |||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "GIGANTEA: a circadian clock-controlled gene that regulates photoperiodic flowering in Arabidopsis and encodes a protein with several possible membrane-spanning domains." Fowler S., Lee K., Onouchi H., Samach A., Richardson K., Morris B., Coupland G., Putterill J. EMBO J. 18:4679-4688(1999) [PubMed: 10469647] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Columbia. |
| [2] | "Control of circadian rhythms and photoperiodic flowering by the Arabidopsis GIGANTEA gene." Park D.H., Somers D.E., Kim Y.S., Choy Y.H., Lim H.K., Soh M.S., Kim H.J., Kay S.A., Nam H.G. Science 285:1579-1582(1999) [PubMed: 10477524] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Columbia. Tissue: Leaf and Stem. |
| [3] | "Sequence analysis of a 24-kb contiguous genomic region at the Arabidopsis thaliana PFL locus on chromosome 1." Terryn N., Neyt P., de Clercq R., de Keyser A., van den Daele H., Ardiles W., Dehais P., Rouze P., Gielen J., Villarroel R., van Montagu M. FEBS Lett. 416:156-160(1997) [PubMed: 9369203] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: cv. Columbia. |
| [4] | "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. Davis R.W.Nature 408:816-820(2000) [PubMed: 11130712] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia. |
| [5] | "GIGANTEA is a nuclear protein involved in phytochrome signaling in Arabidopsis." Huq E., Tepperman J.M., Quail P.H. Proc. Natl. Acad. Sci. U.S.A. 97:9789-9794(2000) [PubMed: 10920210] [Abstract] Cited for: FUNCTION, SUBCELLULAR LOCATION. |
| [6] | "SPINDLY and GIGANTEA interact and act in Arabidopsis thaliana pathways involved in light responses, flowering, and rhythms in cotyledon movements." Tseng T.-S., Salome P.A., McClung C.R., Olszewski N.E. Plant Cell 16:1550-1563(2004) [PubMed: 15155885] [Abstract] Cited for: INTERACTION WITH SPY. |
Cross-references
Sequence databases | |
|---|---|
| AJ133786 mRNA. Translation: CAB56039.1. AF105064 mRNA. Translation: AAF00092.1. AF076686 Genomic DNA. Translation: AAF00023.1. Sequence problems. Y12227 Genomic DNA. Translation: CAA72908.1. Sequence problems. AC003979 Genomic DNA. Translation: AAC25507.1. Sequence problems. | |
| IPI | IPI00531066. |
| PIR | T52575. |
| RefSeq | NP_564180.1. |
| UniGene | At.209 |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| IntAct | Q9SQI2. 5 interactions. |
Proteomic databases | |
| PRIDE | Q9SQI2. |
Genome annotation databases | |
| GeneID | 838883. |
| GenomeReviews | Gene locus AT1G22770 in contig CT485782_GR. |
| KEGG | ath:AT1G22770. |
| NMPDR | fig|3702.1.peg.2647. |
Organism-specific databases | |
| TAIR | At1g22770. |
Phylogenomic databases | |
| OMA | Q9SQI2. EPYARLF. |
Gene expression databases | |
| ArrayExpress | Q9SQI2. |
| GermOnline | AT1G22770. Arabidopsis thaliana. |
Family and domain databases | |
| ProtoNet | Search... |
Entry information
| Entry name | GIGAN_ARATH | ||||||||
| Accession | Primary (citable) accession number: Q9SQI2 Secondary accession number(s): O64381, O80545, Q9S7N0 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | PPAP (Plant Proteome Annotation Project) | ||||||||
Relevant documents
| Arabidopsis thaliana Arabidopsis thaliana: entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with


