Q9SNN0 (SPE1_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Arginine decarboxylase 1
Short name=ARGDC1
Short name=OsADC1
EC=4.1.1.19

Gene names

Name:	ADC1
Ordered Locus Names:	Os06g0131300, LOC_Os06g04070
ORF Names:	P0493C11.18

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	702 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	L-arginine = agmatine + CO2.
Cofactor	Pyridoxal phosphate By similarity. Magnesium By similarity.
Pathway	Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1.
Tissue specificity	Expressed in roots, leaves and stems (at protein level). Ref.1 Ref.2
Induction	By cold stress. Ref.1
Sequence similarities	Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.

Ontologies

Keywords
Biological process	Putrescine biosynthesis Spermidine biosynthesis
Ligand	Magnesium Pyridoxal phosphate
Molecular function	Decarboxylase Lyase
Gene Ontology (GO)
Biological process	arginine catabolic process Inferred from electronic annotation. Source: InterPro putrescine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW response to cold Inferred from expression pattern Ref.1. Source: UniProtKB spermidine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	arginine decarboxylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 702	702	Arginine decarboxylase 1		PRO_0000149952
Regions
	Region	336 – 346	11	Substrate-binding By similarity
	Compositional bias	31 – 38	8	Poly-Ala
Amino acid modifications
	Modified residue	151	1	N6-(pyridoxal phosphate)lysine By similarity
Experimental info
	Sequence conflict	235	1	V → M in ABY47890. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Q9SNN0 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 3B6B8E7AF4959126	FASTA	702	74,064
	10 20 30 40 50 60 MPALAVDAAA PVAHAFACDA ARFPAPLLGP AAAAAAVAEK PDAAAWSADL SSALYNVDGW 70 80 90 100 110 120 GAPYFFVNDD GDVAVRPHGA ATLPGQEIDL AKVVAKAAGP RSGGGLGLPL PLLVRFPDVL 130 140 150 160 170 180 RHRVEALNAA FDYAVRSTGY GGRYQGVYPV KCNQDRHVVE DIVEFGEPFR FGLEAGSKPE 190 200 210 220 230 240 LLLAMSCLAA RGNPDALLIC NGYKDDEYVS LALIARTMGL NTVIVLEQEE ELDIVVDASR 250 260 270 280 290 300 RLGVRPVVGM RAKLRTKHAG HFGSTSGEKG KFGLNAAQIL SVVAKLKTLG MLDCLQLLHF 310 320 330 340 350 360 HIGSQIPTTA LLGDGVGEAA QIYCELARLG AAMRVIDVGG GLGIDYDGSH SAQTDMSVAY 370 380 390 400 410 420 SLEEYAAAVV AAVGRVCDRK GVAHPIICSE SGRALVSHHS VLVFEAFSAS APGRIDPATG 430 440 450 460 470 480 YLLDELTDDC HADYRNLMAA AVRGDFDTCA LYADQLKRRC ADQFKDGVLG LEHLAAVDSL 490 500 510 520 530 540 CEIVARGMGA AEPPRTYHIN LSVFTSLPDM WAIGQMFPII PIQRLGERPA VDGVLSDLTC 550 560 570 580 590 600 DSDGKVDHFI GGRHSLPLHE LPVHGTRGYY LGMFLGGAYQ EALGGLHNLF GGPSVVRVSQ 610 620 630 640 650 660 SDGPHCFAVT RAAAGPSCAD VLRSMQHEPE VMFEVLKQRT DGATAAALAR AFGAMPYLSF 670 680 690 700 DPEAAAMASG ESSGMSSDSE GSAAGAAEED DDEWEFMRGL TV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Molecular cloning and characterization of an arginine decarboxylase gene up-regulated by chilling stress in rice seedlings." Akiyama T., Jin S. J. Plant Physiol. 164:645-654(2007) [PubMed: 16769152] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, INDUCTION.
[2]	"Molecular characterization of the Arginine decarboxylase gene family in rice." Peremarti A., Bassie L., Zhu C., Christou P., Capell T. Transgenic Res. 19:785-797(2010) [PubMed: 20082138] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY. Strain: cv. Eyi 105.
[3]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed: 16100779] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[4]	"The rice annotation project database (RAP-DB): 2008 update." The rice annotation project (RAP) Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed: 18089549] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY604047 mRNA. Translation: AAT37534.1. EU220429 mRNA. Translation: ABY47890.1. AP000559 Genomic DNA. Translation: BAA84799.1. AP008212 Genomic DNA. Translation: BAF18609.1.
RefSeq	NP_001056695.1. NM_001063230.1.
UniGene	Os.75600.
3D structure databases
ProteinModelPortal	Q9SNN0.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9SNN0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os06g04070.1; LOC_Os06g04070.1; LOC_Os06g04070.
GeneID	4340008.
KEGG	osa:4340008.
Organism-specific databases
Gramene	Q9SNN0.
Phylogenomic databases
GeneTree	EPGT00050000019086.
OMA	LICNGYK.
PhylomeDB	Q9SNN0.
ProtClustDB	PLN02439.
Family and domain databases
InterPro	IPR009006. Ala_racemase/Decarboxylase_C. IPR002985. Arg_decrbxlase. IPR022643. De-COase2_C. IPR022644. De-COase2_N. IPR022653. De-COase2_pyr-phos_BS. IPR000183. Orn/DAP/Arg_de-COase. [Graphical view]
Gene3D	G3DSA:2.40.37.10. Ala_racemase/Decarboxylase_C. 2 hits.
KO	K01583.
PANTHER	PTHR11482:SF3. Arg_decrbxlase. 1 hit.
Pfam	PF02784. Orn_Arg_deC_N. 1 hit. PF00278. Orn_DAP_Arg_deC. 1 hit. [Graphical view]
PIRSF	PIRSF001336. Arg_decrbxlase. 1 hit.
PRINTS	PR01180. ARGDCRBXLASE. PR01179. ODADCRBXLASE.
TIGRFAMs	TIGR01273. SpeA. 1 hit.
PROSITE	PS00878. ODR_DC_2_1. 1 hit. PS00879. ODR_DC_2_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SPE1_ORYSJ

Accession

Primary (citable) accession number: Q9SNN0
Secondary accession number(s): A9YLB8, Q0DEW4, Q6J285

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	May 1, 2000
Last modified:	November 16, 2011
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program