Reviewed, UniProtKB/Swiss-Prot Q9SMM0 (PGMP_BRANA)

Names and origin

Protein names

Recommended name:
    Phosphoglucomutase, chloroplastic
      Short name=PGM
    EC=5.4.2.2
Alternative name(s):
    Glucose phosphomutase

Gene names

Name:

PGMP

Organism

Brassica napus (Rape)

Taxonomic identifier

3708 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Brassica

Protein attributes

Sequence length	629 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	This enzyme participates in both the breakdown and synthesis of glucose By similarity.
Catalytic activity	Alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.
Cofactor	Binds 1 magnesium ion per subunit By similarity.
Subcellular location	Plastid › chloroplast.
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glucose metabolism
Cellular component	Chloroplast Plastid
Domain	Transit peptide
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Gene Ontology (GO)
Biological process	glucose metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	chloroplast Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglucomutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – 69	69	Chloroplast Potential
	Chain	70 – 629	560	Phosphoglucomutase, chloroplastic		PRO_0000023896
Sites
	Active site	187	1	Phosphoserine intermediate By similarity
	Metal binding	187	1	Magnesium; via phosphate group By similarity
	Metal binding	352	1	Magnesium By similarity
	Metal binding	354	1	Magnesium By similarity
	Metal binding	356	1	Magnesium By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9SMM0-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: D67A6937B7B60F1A	FASTA	629	68,554
	10 20 30 40 50 60 MSSTYARFDT VFLLSRFAGA KYSPLWPSSS SSSHSSLLSS GIHLRAKPNS RLRSVTGASS 70 80 90 100 110 120 SSSGPIIAGS ESIEIKSLPT KPIEGQKTGT SGLRKKVKVF MQDNYLANWI QALFNSLPLE 130 140 150 160 170 180 DYKDATLVLG GDGRYFNKEA SQIIIKIAAG NGVGKILVGQ EGILSTPAVS AVIRKRKANG 190 200 210 220 230 240 GFIMSASHNP GGPEYDWGIK FNYSSGQPAP ESITDKIYGN TLSISEIKVA EIPDIDLSHV 250 260 270 280 290 300 GVTKYGNFSV EVIDPISDYL ELMEDVFDFD LIRGLLSRSD FGFMFDAMHA VTGAYAKPIF 310 320 330 340 350 360 VDNLEAKPDS ISNGVPLEDF GHGHPDPNLT YAKDLVDVMY RDDGPDFGAA SDGDGDRNMV 370 380 390 400 410 420 LGNKFFVTPS DSVAIIAANA QEAIPYFRAG PKGLARSMPT SGALDRVAEK LKLPFFEVPT 430 440 450 460 470 480 GWKFFGNLMD AGKLSICGEE SFGTGSDHIR EKDGIWAVLA WLSILAHRIK DKKPGEKLVS 490 500 510 520 530 540 VADVVNEYWA TYGRNFFSRY DYEECESEGA NKMIEYLRDI VAKSKAGENY GNYVLQFADD 550 560 570 580 590 600 FSYKDPVDGS VASKQGVRFV FTDGSRIIYR LSGNGSAGAT VRIYIEQFEP DVSKHDVDAQ 610 620 IAIKPLIDLA LSVSKLKEFT GREKPTVIT

References

[1]

"The rug3 locus of pea encodes plastidial phosphoglucomutase." Harrison C.J., Mould R.M., Leech M.J., Johnson S.A., Turner L., Schreck S.L., Baird K.M., Jack P.L., Rawsthorne S., Hedley C.L., Wang T.L. Plant Physiol. 122:1187-1192(2000) [PubMed: 10759514] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Ascari.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AJ250771 mRNA. Translation: CAB60109.1.
3D structure databases
HSSP	HSSP built from PDB template 3PMG based on UniProtKB P00949.
ModBase	Search...
Enzyme and pathway databases
BRENDA	5.4.2.2. 393.
Family and domain databases
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. A-D-PHexomutase_N. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PGMP_BRANA

Accession

Primary (citable) accession number: Q9SMM0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 24, 2001
Last sequence update:	May 1, 2000
Last modified:	June 16, 2009
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)