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Protein

Glutathione S-transferase F3

Gene

GSTF3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Binds a series of heterocyclic compounds, including lumichrome, harmane, norharmane and indole-3-aldehyde. May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

GO - Molecular functioni

GO - Biological processi

  • glutathione metabolic process Source: GO_Central
  • response to oomycetes Source: TAIR
  • toxin catabolic process Source: TAIR

Keywordsi

Molecular functionTransferase
Biological processDetoxification

Enzyme and pathway databases

BioCyciARA:AT2G02930-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase F3 (EC:2.5.1.18)
Short name:
AtGSTF3
Alternative name(s):
GST class-phi member 3
Glutathione S-transferase 16
Gene namesi
Name:GSTF3
Synonyms:GST16
Ordered Locus Names:At2g02930
ORF Names:T17M13.10
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G02930
TAIRilocus:2056685 AT2G02930

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001858531 – 212Glutathione S-transferase F3Add BLAST212

Proteomic databases

PaxDbiQ9SLM6
PRIDEiQ9SLM6

Expressioni

Gene expression databases

ExpressionAtlasiQ9SLM6 baseline and differential
GenevisibleiQ9SLM6 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G02930.1

Structurei

3D structure databases

ProteinModelPortaliQ9SLM6
SMRiQ9SLM6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 83GST N-terminalAdd BLAST82
Domaini93 – 212GST C-terminalAdd BLAST120

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni12 – 13Glutathione bindingBy similarity2
Regioni41 – 42Glutathione bindingBy similarity2
Regioni54 – 55Glutathione bindingBy similarity2
Regioni67 – 68Glutathione bindingBy similarity2

Sequence similaritiesi

Belongs to the GST superfamily. Phi family.Curated

Phylogenomic databases

eggNOGiKOG0867 Eukaryota
COG0625 LUCA
HOGENOMiHOG000125746
InParanoidiQ9SLM6
KOiK00799
OMAiVCESRAI
OrthoDBiEOG09360M18
PhylomeDBiQ9SLM6

Family and domain databases

CDDicd03187 GST_C_Phi, 1 hit
InterProiView protein in InterPro
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR004046 GST_C
IPR034347 GST_Phi_C
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF00043 GST_C, 1 hit
PF02798 GST_N, 1 hit
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

Q9SLM6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGIKVFGHP ASTSTRRVLI ALHEKNLDFE LVHVELKDGE HKKEPFLSRN
60 70 80 90 100
PFGQVPAFED GDLKLFESRA ITQYIAHRYE NQGTNLLPAD SKNIAQYAIM
110 120 130 140 150
SIGIQVEAHQ FDPVASKLAW EQVFKFNYGL NTDQAVVAEE EAKLAKVLDV
160 170 180 190 200
YEARLKEFKY LAGETFTLTD LHHIPVIQYL LGTPTKKLFT ERPRVNEWVA
210
EITKRPASEK VL
Length:212
Mass (Da):24,121
Last modified:May 1, 2000 - v1
Checksum:i73818A85E6D05A59
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti96Q → R in BAF01093 (Ref. 5) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF288181 mRNA Translation: AAG30130.1
AC004138 Genomic DNA Translation: AAC32912.1
CP002685 Genomic DNA Translation: AEC05642.1
BT024921 mRNA Translation: ABD94077.1
AK229226 mRNA Translation: BAF01093.1
PIRiD84442
RefSeqiNP_178394.1, NM_126346.3
UniGeneiAt.22195
At.24972

Genome annotation databases

EnsemblPlantsiAT2G02930.1; AT2G02930.1; AT2G02930
GeneIDi814822
GrameneiAT2G02930.1; AT2G02930.1; AT2G02930
KEGGiath:AT2G02930

Similar proteinsi

Entry informationi

Entry nameiGSTF3_ARATH
AccessioniPrimary (citable) accession number: Q9SLM6
Secondary accession number(s): Q0WP56, Q1WWI5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: May 1, 2000
Last modified: April 25, 2018
This is version 131 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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