Reviewed, UniProtKB/Swiss-Prot Q9SLM6 (GST16_ARATH)

Names and origin

Protein names

Recommended name:
    Glutathione S-transferase 16
    EC=2.5.1.18
Alternative name(s):
    GST class-phi

Gene names

Name:	GST16
Ordered Locus Names:	At2g02930
ORF Names:	T17M13.10

Organism

Arabidopsis thaliana (Mouse-ear cress) [Complete proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis

Protein attributes

Sequence length	212 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. In plants, may have a detoxification role against certain herbicides By similarity.
Catalytic activity	RX + glutathione = HX + R-S-glutathione.
Subcellular location	Cytoplasm Probable.
Sequence similarities	Belongs to the GST superfamily. Phi family. Contains 1 GST C-terminal domain. Contains 1 GST N-terminal domain.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	toxin catabolic process Traceable author statement. Source: TAIR
Cellular component	cytoplasm Non-traceable author statement. Source: TAIR plasma membrane Inferred from direct assay. Source: TAIR
Molecular function	glutathione transferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 212	212	Glutathione S-transferase 16		PRO_0000185853
Regions
	Domain	2 – 83	82	GST N-terminal
	Domain	93 – 212	120	GST C-terminal

Sequences

	Sequence		Length	Mass (Da)
	Q9SLM6-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 73818A85E6D05A59	FASTA	212	24,121
	10 20 30 40 50 60 MAGIKVFGHP ASTSTRRVLI ALHEKNLDFE LVHVELKDGE HKKEPFLSRN PFGQVPAFED 70 80 90 100 110 120 GDLKLFESRA ITQYIAHRYE NQGTNLLPAD SKNIAQYAIM SIGIQVEAHQ FDPVASKLAW 130 140 150 160 170 180 EQVFKFNYGL NTDQAVVAEE EAKLAKVLDV YEARLKEFKY LAGETFTLTD LHHIPVIQYL 190 200 210 LGTPTKKLFT ERPRVNEWVA EITKRPASEK VL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Analysis of the glutathione S-transferase family in Arabidopsis thaliana." Wagner U., Mauch F. Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Columbia.
[2]	"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana." Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C. Nature 402:761-768(1999) [PubMed: 10617197] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF288181 mRNA. Translation: AAG30130.1. AC004138 Genomic DNA. Translation: AAC32912.1.
IPI	IPI00532945.
PIR	D84442.
RefSeq	NP_178394.1.
UniGene	At.22195 At.24972
3D structure databases
HSSP	HSSP built from PDB template 1GNW based on UniProtKB P46422.
SMR	Q9SLM6. Positions 3-211.
ModBase	Search...
Proteomic databases
PRIDE	Q9SLM6.
ProMEX	Q9SLM6.
Genome annotation databases
GeneID	814822.
GenomeReviews	Gene locus AT2G02930 in contig CT485783_GR.
KEGG	ath:AT2G02930.
NMPDR	fig|3702.1.peg.7888.
Organism-specific databases
TAIR	At2g02930.
Phylogenomic databases
OMA	Q9SLM6. KASTIPA.
Enzyme and pathway databases
BRENDA	2.5.1.18. 302.
Gene expression databases
ArrayExpress	Q9SLM6.
GermOnline	AT2G02930. Arabidopsis thaliana.
Family and domain databases
InterPro	IPR010987. Glutathione-S-Trfase_C-like. IPR004045. Glutathione_S-Trfase_N. IPR017933. Glutathione_S_Trfase/Cl_chnl_C. IPR004046. GST_C. IPR012335. Thioredoxin_fold. [Graphical view]
Gene3D	G3DSA:1.20.1050.10. GST_C_like. 1 hit. G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.
Pfam	PF00043. GST_C. 1 hit. PF02798. GST_N. 1 hit. [Graphical view]
PROSITE	PS50405. GST_CTER. 1 hit. PS50404. GST_NTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GST16_ARATH

Accession

Primary (citable) accession number: Q9SLM6

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 11, 2001
Last sequence update:	May 1, 2000
Last modified:	June 16, 2009
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)