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Q9SLG9

- PI5K5_ARATH

UniProt

Q9SLG9 - PI5K5_ARATH

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Protein

Phosphatidylinositol 4-phosphate 5-kinase 5

Gene
PIP5K5, At2g41210, T3K9.2
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.

GO - Molecular functioni

  1. 1-phosphatidylinositol-4-phosphate 5-kinase activity Source: TAIR
  2. ATP binding Source: UniProtKB-KW

GO - Biological processi

  1. phosphatidylinositol metabolic process Source: TAIR
  2. phosphatidylinositol phosphorylation Source: GOC
  3. plant-type cell wall modification Source: TAIR
  4. pollen germination Source: TAIR
  5. pollen tube growth Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT2G41210-MONOMER.
ReactomeiREACT_187642. Synthesis of PIPs at the plasma membrane.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphatidylinositol 4-phosphate 5-kinase 5 (EC:2.7.1.68)
Short name:
AtPIP5K5
Alternative name(s):
1-phosphatidylinositol 4-phosphate kinase 5
Diphosphoinositide kinase 5
PtdIns(4)P-5-kinase 5
Gene namesi
Name:PIP5K5
Ordered Locus Names:At2g41210
ORF Names:T3K9.2
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 2

Organism-specific databases

TAIRiAT2G41210.

Subcellular locationi

GO - Cellular componenti

  1. apical plasma membrane Source: TAIR
  2. cytosol Source: TAIR
  3. pollen tube Source: TAIR
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 772772Phosphatidylinositol 4-phosphate 5-kinase 5PRO_0000185477Add
BLAST

Proteomic databases

PaxDbiQ9SLG9.
PRIDEiQ9SLG9.

Expressioni

Gene expression databases

GenevestigatoriQ9SLG9.

Interactioni

Protein-protein interaction databases

MINTiMINT-8060064.
STRINGi3702.AT2G41210.1-P.

Structurei

3D structure databases

ProteinModelPortaliQ9SLG9.
SMRiQ9SLG9. Positions 389-633.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati75 – 9723MORN 1Add
BLAST
Repeati98 – 12023MORN 2Add
BLAST
Repeati121 – 14323MORN 3Add
BLAST
Repeati144 – 16623MORN 4Add
BLAST
Repeati167 – 18923MORN 5Add
BLAST
Repeati190 – 21223MORN 6Add
BLAST
Repeati213 – 23523MORN 7Add
BLAST
Repeati236 – 25722MORN 8Add
BLAST
Domaini377 – 768392PIPKAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni728 – 74922Activation loop By similarityAdd
BLAST

Sequence similaritiesi

Contains 8 MORN repeats.
Contains 1 PIPK domain.

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiCOG4642.
HOGENOMiHOG000193875.
InParanoidiQ9SLG9.
KOiK00889.
OMAiWKNGTIC.
PhylomeDBiQ9SLG9.

Family and domain databases

Gene3Di3.30.800.10. 1 hit.
3.30.810.10. 2 hits.
InterProiIPR003409. MORN.
IPR017163. PIno-4-P-5_kinase_pln.
IPR023610. PInositol-4-P-5-kinase.
IPR027483. PInositol-4-P-5-kinase_C.
IPR002498. PInositol-4-P-5-kinase_core.
IPR027484. PInositol-4-P-5-kinase_N.
IPR016034. PInositol-4P-5-kinase_core_sub.
[Graphical view]
PANTHERiPTHR23086. PTHR23086. 1 hit.
PfamiPF02493. MORN. 8 hits.
PF01504. PIP5K. 1 hit.
[Graphical view]
PIRSFiPIRSF037274. PIP5K_plant_prd. 1 hit.
SMARTiSM00698. MORN. 7 hits.
SM00330. PIPKc. 1 hit.
[Graphical view]
PROSITEiPS51455. PIPK. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9SLG9-1 [UniParc]FASTAAdd to Basket

« Hide

MSKDQSYVLK AWEVTVRKTQ QAKKRANSVF GTVSVAPHTD NDTTTDDNDD    50
ETTTNRSSLE EFYHAERVLP NGDYYTGQWY DSFPHGHGKY LWTDGCMYIG 100
DWYNGKTMGN GKFGWPSGAT YEGEFKSGYM DGIGTYTGPS GDAYKGQWVM 150
NLKHGHGVKS FANGDAYDGE WRRGLQEGQG KYQWSDGSYY IGEWKNGTIC 200
GKGSFVWTNG NRYDGFWDEG FPRGNGTFKW DNGSFYVGHW SKDPEEMNGT 250
YYPSGNEGNL EWDPKDLFNN LSEYTICSGE RVPTLPSQKK LSVWNSSKRI 300
EKPRRTSVDG RVSVGVDRAF EKMNMWGNEI GEGGADMRKE LDAELMRLDA 350
EGLQSLKSSP VPMKLPKAGR KQGETISKGH RNYELMLNLQ LGIRHSVGRQ 400
APAASLDLKP SAFDPKDKIW RRFPREGTKY TPPHQSTEFK WKDYCPLVFR 450
SLRKLFKVDP ADYMLSICGN DALRELSSPG KSGSFFYLTN DDRYMIKTMK 500
KSETKVLLGM LAAYYNHVRA FENSLVIRFF GLHCVKLNGP TQKKVRFVIM 550
GNLFCSKYSV HRRFDLKGSS LGRTTDKPES EIDSNTILKD LDLNFIFRLQ 600
KAWYQEFIRQ IDKDCEFLEQ ERIMDYSLLV GIHFREASVA GELIPSGART 650
PIGESEEESG PRLSRAEVDE LLSDPSRWAS IRLGTNMPAR AERTMRKNDS 700
ELQLVGEPTG EFYEVVMIFG IIDILQDYDI SKKLEHAYKS IQYDPSSISA 750
VDPRQYSRRF RDFIFKVFTD DN 772
Length:772
Mass (Da):88,204
Last modified:May 1, 2000 - v1
Checksum:iD189D4B24D517152
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF260903 mRNA. Translation: AAK49397.1.
AC004261 Genomic DNA. Translation: AAM14925.1.
CP002685 Genomic DNA. Translation: AEC09944.1.
PIRiT02098.
RefSeqiNP_181654.1. NM_129686.1.
UniGeneiAt.13170.

Genome annotation databases

EnsemblPlantsiAT2G41210.1; AT2G41210.1; AT2G41210.
GeneIDi818720.
KEGGiath:AT2G41210.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF260903 mRNA. Translation: AAK49397.1 .
AC004261 Genomic DNA. Translation: AAM14925.1 .
CP002685 Genomic DNA. Translation: AEC09944.1 .
PIRi T02098.
RefSeqi NP_181654.1. NM_129686.1.
UniGenei At.13170.

3D structure databases

ProteinModelPortali Q9SLG9.
SMRi Q9SLG9. Positions 389-633.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

MINTi MINT-8060064.
STRINGi 3702.AT2G41210.1-P.

Proteomic databases

PaxDbi Q9SLG9.
PRIDEi Q9SLG9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT2G41210.1 ; AT2G41210.1 ; AT2G41210 .
GeneIDi 818720.
KEGGi ath:AT2G41210.

Organism-specific databases

TAIRi AT2G41210.

Phylogenomic databases

eggNOGi COG4642.
HOGENOMi HOG000193875.
InParanoidi Q9SLG9.
KOi K00889.
OMAi WKNGTIC.
PhylomeDBi Q9SLG9.

Enzyme and pathway databases

BioCyci ARA:AT2G41210-MONOMER.
Reactomei REACT_187642. Synthesis of PIPs at the plasma membrane.

Gene expression databases

Genevestigatori Q9SLG9.

Family and domain databases

Gene3Di 3.30.800.10. 1 hit.
3.30.810.10. 2 hits.
InterProi IPR003409. MORN.
IPR017163. PIno-4-P-5_kinase_pln.
IPR023610. PInositol-4-P-5-kinase.
IPR027483. PInositol-4-P-5-kinase_C.
IPR002498. PInositol-4-P-5-kinase_core.
IPR027484. PInositol-4-P-5-kinase_N.
IPR016034. PInositol-4P-5-kinase_core_sub.
[Graphical view ]
PANTHERi PTHR23086. PTHR23086. 1 hit.
Pfami PF02493. MORN. 8 hits.
PF01504. PIP5K. 1 hit.
[Graphical view ]
PIRSFi PIRSF037274. PIP5K_plant_prd. 1 hit.
SMARTi SM00698. MORN. 7 hits.
SM00330. PIPKc. 1 hit.
[Graphical view ]
PROSITEi PS51455. PIPK. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning and functional analysis of a novel Arabidopsis phosphatidylinositol-4-phosphate 5-kinase."
    Abd El-Haliem M., Elge S., Mueller-Roeber B.
    Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  3. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  4. "Inositol phospholipid metabolism in Arabidopsis. Characterized and putative isoforms of inositol phospholipid kinase and phosphoinositide-specific phospholipase C."
    Mueller-Roeber B., Pical C.
    Plant Physiol. 130:22-46(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiPI5K5_ARATH
AccessioniPrimary (citable) accession number: Q9SLG9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: May 1, 2000
Last modified: September 3, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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