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Q9SLG9

- PI5K5_ARATH

UniProt

Q9SLG9 - PI5K5_ARATH

Protein

Phosphatidylinositol 4-phosphate 5-kinase 5

Gene

PIP5K5

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 95 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.

    GO - Molecular functioni

    1. 1-phosphatidylinositol-4-phosphate 5-kinase activity Source: TAIR
    2. ATP binding Source: UniProtKB-KW

    GO - Biological processi

    1. phosphatidylinositol metabolic process Source: TAIR
    2. phosphatidylinositol phosphorylation Source: GOC
    3. plant-type cell wall modification Source: TAIR
    4. pollen germination Source: TAIR
    5. pollen tube growth Source: TAIR

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciARA:AT2G41210-MONOMER.
    ReactomeiREACT_187642. Synthesis of PIPs at the plasma membrane.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphatidylinositol 4-phosphate 5-kinase 5 (EC:2.7.1.68)
    Short name:
    AtPIP5K5
    Alternative name(s):
    1-phosphatidylinositol 4-phosphate kinase 5
    Diphosphoinositide kinase 5
    PtdIns(4)P-5-kinase 5
    Gene namesi
    Name:PIP5K5
    Ordered Locus Names:At2g41210
    ORF Names:T3K9.2
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 2

    Organism-specific databases

    TAIRiAT2G41210.

    Subcellular locationi

    GO - Cellular componenti

    1. apical plasma membrane Source: TAIR
    2. cytosol Source: TAIR
    3. pollen tube Source: TAIR

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 772772Phosphatidylinositol 4-phosphate 5-kinase 5PRO_0000185477Add
    BLAST

    Proteomic databases

    PaxDbiQ9SLG9.
    PRIDEiQ9SLG9.

    Expressioni

    Gene expression databases

    GenevestigatoriQ9SLG9.

    Interactioni

    Protein-protein interaction databases

    MINTiMINT-8060064.
    STRINGi3702.AT2G41210.1-P.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9SLG9.
    SMRiQ9SLG9. Positions 389-633.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati75 – 9723MORN 1Add
    BLAST
    Repeati98 – 12023MORN 2Add
    BLAST
    Repeati121 – 14323MORN 3Add
    BLAST
    Repeati144 – 16623MORN 4Add
    BLAST
    Repeati167 – 18923MORN 5Add
    BLAST
    Repeati190 – 21223MORN 6Add
    BLAST
    Repeati213 – 23523MORN 7Add
    BLAST
    Repeati236 – 25722MORN 8Add
    BLAST
    Domaini377 – 768392PIPKPROSITE-ProRule annotationAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni728 – 74922Activation loopBy similarityAdd
    BLAST

    Sequence similaritiesi

    Contains 8 MORN repeats.Curated
    Contains 1 PIPK domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    eggNOGiCOG4642.
    HOGENOMiHOG000193875.
    InParanoidiQ9SLG9.
    KOiK00889.
    OMAiWKNGTIC.
    PhylomeDBiQ9SLG9.

    Family and domain databases

    Gene3Di3.30.800.10. 1 hit.
    3.30.810.10. 2 hits.
    InterProiIPR003409. MORN.
    IPR017163. PIno-4-P-5_kinase_pln.
    IPR023610. PInositol-4-P-5-kinase.
    IPR027483. PInositol-4-P-5-kinase_C.
    IPR002498. PInositol-4-P-5-kinase_core.
    IPR027484. PInositol-4-P-5-kinase_N.
    IPR016034. PInositol-4P-5-kinase_core_sub.
    [Graphical view]
    PANTHERiPTHR23086. PTHR23086. 1 hit.
    PfamiPF02493. MORN. 8 hits.
    PF01504. PIP5K. 1 hit.
    [Graphical view]
    PIRSFiPIRSF037274. PIP5K_plant_prd. 1 hit.
    SMARTiSM00698. MORN. 7 hits.
    SM00330. PIPKc. 1 hit.
    [Graphical view]
    PROSITEiPS51455. PIPK. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9SLG9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSKDQSYVLK AWEVTVRKTQ QAKKRANSVF GTVSVAPHTD NDTTTDDNDD    50
    ETTTNRSSLE EFYHAERVLP NGDYYTGQWY DSFPHGHGKY LWTDGCMYIG 100
    DWYNGKTMGN GKFGWPSGAT YEGEFKSGYM DGIGTYTGPS GDAYKGQWVM 150
    NLKHGHGVKS FANGDAYDGE WRRGLQEGQG KYQWSDGSYY IGEWKNGTIC 200
    GKGSFVWTNG NRYDGFWDEG FPRGNGTFKW DNGSFYVGHW SKDPEEMNGT 250
    YYPSGNEGNL EWDPKDLFNN LSEYTICSGE RVPTLPSQKK LSVWNSSKRI 300
    EKPRRTSVDG RVSVGVDRAF EKMNMWGNEI GEGGADMRKE LDAELMRLDA 350
    EGLQSLKSSP VPMKLPKAGR KQGETISKGH RNYELMLNLQ LGIRHSVGRQ 400
    APAASLDLKP SAFDPKDKIW RRFPREGTKY TPPHQSTEFK WKDYCPLVFR 450
    SLRKLFKVDP ADYMLSICGN DALRELSSPG KSGSFFYLTN DDRYMIKTMK 500
    KSETKVLLGM LAAYYNHVRA FENSLVIRFF GLHCVKLNGP TQKKVRFVIM 550
    GNLFCSKYSV HRRFDLKGSS LGRTTDKPES EIDSNTILKD LDLNFIFRLQ 600
    KAWYQEFIRQ IDKDCEFLEQ ERIMDYSLLV GIHFREASVA GELIPSGART 650
    PIGESEEESG PRLSRAEVDE LLSDPSRWAS IRLGTNMPAR AERTMRKNDS 700
    ELQLVGEPTG EFYEVVMIFG IIDILQDYDI SKKLEHAYKS IQYDPSSISA 750
    VDPRQYSRRF RDFIFKVFTD DN 772
    Length:772
    Mass (Da):88,204
    Last modified:May 1, 2000 - v1
    Checksum:iD189D4B24D517152
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF260903 mRNA. Translation: AAK49397.1.
    AC004261 Genomic DNA. Translation: AAM14925.1.
    CP002685 Genomic DNA. Translation: AEC09944.1.
    PIRiT02098.
    RefSeqiNP_181654.1. NM_129686.1.
    UniGeneiAt.13170.

    Genome annotation databases

    EnsemblPlantsiAT2G41210.1; AT2G41210.1; AT2G41210.
    GeneIDi818720.
    KEGGiath:AT2G41210.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF260903 mRNA. Translation: AAK49397.1 .
    AC004261 Genomic DNA. Translation: AAM14925.1 .
    CP002685 Genomic DNA. Translation: AEC09944.1 .
    PIRi T02098.
    RefSeqi NP_181654.1. NM_129686.1.
    UniGenei At.13170.

    3D structure databases

    ProteinModelPortali Q9SLG9.
    SMRi Q9SLG9. Positions 389-633.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    MINTi MINT-8060064.
    STRINGi 3702.AT2G41210.1-P.

    Proteomic databases

    PaxDbi Q9SLG9.
    PRIDEi Q9SLG9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT2G41210.1 ; AT2G41210.1 ; AT2G41210 .
    GeneIDi 818720.
    KEGGi ath:AT2G41210.

    Organism-specific databases

    TAIRi AT2G41210.

    Phylogenomic databases

    eggNOGi COG4642.
    HOGENOMi HOG000193875.
    InParanoidi Q9SLG9.
    KOi K00889.
    OMAi WKNGTIC.
    PhylomeDBi Q9SLG9.

    Enzyme and pathway databases

    BioCyci ARA:AT2G41210-MONOMER.
    Reactomei REACT_187642. Synthesis of PIPs at the plasma membrane.

    Gene expression databases

    Genevestigatori Q9SLG9.

    Family and domain databases

    Gene3Di 3.30.800.10. 1 hit.
    3.30.810.10. 2 hits.
    InterProi IPR003409. MORN.
    IPR017163. PIno-4-P-5_kinase_pln.
    IPR023610. PInositol-4-P-5-kinase.
    IPR027483. PInositol-4-P-5-kinase_C.
    IPR002498. PInositol-4-P-5-kinase_core.
    IPR027484. PInositol-4-P-5-kinase_N.
    IPR016034. PInositol-4P-5-kinase_core_sub.
    [Graphical view ]
    PANTHERi PTHR23086. PTHR23086. 1 hit.
    Pfami PF02493. MORN. 8 hits.
    PF01504. PIP5K. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF037274. PIP5K_plant_prd. 1 hit.
    SMARTi SM00698. MORN. 7 hits.
    SM00330. PIPKc. 1 hit.
    [Graphical view ]
    PROSITEi PS51455. PIPK. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning and functional analysis of a novel Arabidopsis phosphatidylinositol-4-phosphate 5-kinase."
      Abd El-Haliem M., Elge S., Mueller-Roeber B.
      Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    3. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    4. "Inositol phospholipid metabolism in Arabidopsis. Characterized and putative isoforms of inositol phospholipid kinase and phosphoinositide-specific phospholipase C."
      Mueller-Roeber B., Pical C.
      Plant Physiol. 130:22-46(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiPI5K5_ARATH
    AccessioniPrimary (citable) accession number: Q9SLG9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 25, 2005
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 95 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3