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Protein

Phosphatidylinositol 4-phosphate 5-kinase 5

Gene

PIP5K5

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.

GO - Molecular functioni

  • 1-phosphatidylinositol-4-phosphate 5-kinase activity Source: TAIR
  • ATP binding Source: UniProtKB-KW

GO - Biological processi

  • phosphatidylinositol metabolic process Source: TAIR
  • plant-type cell wall modification Source: TAIR
  • pollen germination Source: TAIR
  • pollen tube growth Source: TAIR

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT2G41210-MONOMER
ReactomeiR-ATH-1660499 Synthesis of PIPs at the plasma membrane
R-ATH-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
R-ATH-8856828 Clathrin-mediated endocytosis

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphatidylinositol 4-phosphate 5-kinase 5 (EC:2.7.1.68)
Short name:
AtPIP5K5
Alternative name(s):
1-phosphatidylinositol 4-phosphate kinase 5
Diphosphoinositide kinase 5
PtdIns(4)P-5-kinase 5
Gene namesi
Name:PIP5K5
Ordered Locus Names:At2g41210
ORF Names:T3K9.2
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G41210
TAIRilocus:2040327 AT2G41210

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001854771 – 772Phosphatidylinositol 4-phosphate 5-kinase 5Add BLAST772

Proteomic databases

PaxDbiQ9SLG9
PRIDEiQ9SLG9

PTM databases

iPTMnetiQ9SLG9

Expressioni

Gene expression databases

ExpressionAtlasiQ9SLG9 baseline and differential
GenevisibleiQ9SLG9 AT

Interactioni

Protein-protein interaction databases

BioGridi4057, 3 interactors
STRINGi3702.AT2G41210.1

Structurei

3D structure databases

ProteinModelPortaliQ9SLG9
SMRiQ9SLG9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati75 – 97MORN 1Add BLAST23
Repeati98 – 120MORN 2Add BLAST23
Repeati121 – 143MORN 3Add BLAST23
Repeati144 – 166MORN 4Add BLAST23
Repeati167 – 189MORN 5Add BLAST23
Repeati190 – 212MORN 6Add BLAST23
Repeati213 – 235MORN 7Add BLAST23
Repeati236 – 257MORN 8Add BLAST22
Domaini377 – 768PIPKPROSITE-ProRule annotationAdd BLAST392

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni728 – 749Activation loopBy similarityAdd BLAST22

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG0229 Eukaryota
COG4642 LUCA
COG5253 LUCA
HOGENOMiHOG000193875
InParanoidiQ9SLG9
KOiK00889
OMAiSVAPHTD
OrthoDBiEOG093602F1
PhylomeDBiQ9SLG9

Family and domain databases

Gene3Di3.30.800.10, 1 hit
3.30.810.10, 2 hits
InterProiView protein in InterPro
IPR003409 MORN
IPR017163 PIno-4-P-5_kinase_pln
IPR023610 PInositol-4-P-5-kinase
IPR027483 PInositol-4-P-5-kinase_C
IPR002498 PInositol-4-P-5-kinase_core
IPR027484 PInositol-4-P-5-kinase_N
PANTHERiPTHR23086 PTHR23086, 1 hit
PfamiView protein in Pfam
PF02493 MORN, 8 hits
PF01504 PIP5K, 1 hit
PIRSFiPIRSF037274 PIP5K_plant_prd, 1 hit
SMARTiView protein in SMART
SM00698 MORN, 7 hits
SM00330 PIPKc, 1 hit
PROSITEiView protein in PROSITE
PS51455 PIPK, 1 hit

Sequencei

Sequence statusi: Complete.

Q9SLG9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKDQSYVLK AWEVTVRKTQ QAKKRANSVF GTVSVAPHTD NDTTTDDNDD
60 70 80 90 100
ETTTNRSSLE EFYHAERVLP NGDYYTGQWY DSFPHGHGKY LWTDGCMYIG
110 120 130 140 150
DWYNGKTMGN GKFGWPSGAT YEGEFKSGYM DGIGTYTGPS GDAYKGQWVM
160 170 180 190 200
NLKHGHGVKS FANGDAYDGE WRRGLQEGQG KYQWSDGSYY IGEWKNGTIC
210 220 230 240 250
GKGSFVWTNG NRYDGFWDEG FPRGNGTFKW DNGSFYVGHW SKDPEEMNGT
260 270 280 290 300
YYPSGNEGNL EWDPKDLFNN LSEYTICSGE RVPTLPSQKK LSVWNSSKRI
310 320 330 340 350
EKPRRTSVDG RVSVGVDRAF EKMNMWGNEI GEGGADMRKE LDAELMRLDA
360 370 380 390 400
EGLQSLKSSP VPMKLPKAGR KQGETISKGH RNYELMLNLQ LGIRHSVGRQ
410 420 430 440 450
APAASLDLKP SAFDPKDKIW RRFPREGTKY TPPHQSTEFK WKDYCPLVFR
460 470 480 490 500
SLRKLFKVDP ADYMLSICGN DALRELSSPG KSGSFFYLTN DDRYMIKTMK
510 520 530 540 550
KSETKVLLGM LAAYYNHVRA FENSLVIRFF GLHCVKLNGP TQKKVRFVIM
560 570 580 590 600
GNLFCSKYSV HRRFDLKGSS LGRTTDKPES EIDSNTILKD LDLNFIFRLQ
610 620 630 640 650
KAWYQEFIRQ IDKDCEFLEQ ERIMDYSLLV GIHFREASVA GELIPSGART
660 670 680 690 700
PIGESEEESG PRLSRAEVDE LLSDPSRWAS IRLGTNMPAR AERTMRKNDS
710 720 730 740 750
ELQLVGEPTG EFYEVVMIFG IIDILQDYDI SKKLEHAYKS IQYDPSSISA
760 770
VDPRQYSRRF RDFIFKVFTD DN
Length:772
Mass (Da):88,204
Last modified:May 1, 2000 - v1
Checksum:iD189D4B24D517152
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF260903 mRNA Translation: AAK49397.1
AC004261 Genomic DNA Translation: AAM14925.1
CP002685 Genomic DNA Translation: AEC09944.1
PIRiT02098
RefSeqiNP_181654.1, NM_129686.2
UniGeneiAt.13170

Genome annotation databases

EnsemblPlantsiAT2G41210.1; AT2G41210.1; AT2G41210
GeneIDi818720
GrameneiAT2G41210.1; AT2G41210.1; AT2G41210
KEGGiath:AT2G41210

Similar proteinsi

Entry informationi

Entry nameiPI5K5_ARATH
AccessioniPrimary (citable) accession number: Q9SLG9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: May 1, 2000
Last modified: April 25, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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