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Protein

Ubiquitin-conjugating enzyme E2 29

Gene

UBC29

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.

Catalytic activityi

S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.PROSITE-ProRule annotation

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.PROSITE-ProRule annotation
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei85Glycyl thioester intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • ubiquitin-protein transferase activity Source: TAIR

GO - Biological processi

  • ubiquitin-dependent protein catabolic process Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Ubl conjugation pathway

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-ATH-174184. Cdc20:Phospho-APC/C mediated degradation of Cyclin A.
R-ATH-179409. APC-Cdc20 mediated degradation of Nek2A.
R-ATH-5689896. Ovarian tumor domain proteases.
R-ATH-8866652. Synthesis of active ubiquitin: roles of E1 and E2 enzymes.
UniPathwayiUPA00143.

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquitin-conjugating enzyme E2 29 (EC:2.3.2.23)
Alternative name(s):
E2 ubiquitin-conjugating enzyme 29
Ubiquitin carrier protein 29
Gene namesi
Name:UBC29
Ordered Locus Names:At2g16740
ORF Names:T24I21.15
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G16740.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003451941 – 148Ubiquitin-conjugating enzyme E2 29Add BLAST148

Proteomic databases

PaxDbiQ9SLE4.

Expressioni

Gene expression databases

GenevisibleiQ9SLE4. AT.

Interactioni

Protein-protein interaction databases

BioGridi1532. 13 interactors.
IntActiQ9SLE4. 10 interactors.
STRINGi3702.AT2G16740.1.

Structurei

3D structure databases

ProteinModelPortaliQ9SLE4.
SMRiQ9SLE4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ubiquitin-conjugating enzyme family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0417. Eukaryota.
COG5078. LUCA.
HOGENOMiHOG000233455.
InParanoidiQ9SLE4.
KOiK06689.
OMAiTGEDMFH.
OrthoDBiEOG0936177B.
PhylomeDBiQ9SLE4.

Family and domain databases

Gene3Di3.10.110.10. 1 hit.
InterProiIPR000608. UBQ-conjugat_E2.
IPR023313. UBQ-conjugating_AS.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view]
PfamiPF00179. UQ_con. 1 hit.
[Graphical view]
SUPFAMiSSF54495. SSF54495. 1 hit.
PROSITEiPS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9SLE4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATRRILKEL KELQRDPPVS CSAGPTGEDM FHWQATIMGP NESPYSGGVF
60 70 80 90 100
LVNIHFPPDY PFKPPKVVFR TKVFHPNINS NGNICLDILK DQWSPALTIS
110 120 130 140
KVLLSICSLL TDPNPDDPLV PEIAHIYKTD KTKYEAMARS WTQKYALF
Length:148
Mass (Da):16,759
Last modified:May 1, 2000 - v1
Checksum:i2A1836C152DC2C12
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ027042 mRNA. Translation: AAY44868.1.
AC005825 Genomic DNA. Translation: AAD24607.1.
CP002685 Genomic DNA. Translation: AEC06533.1.
AY063872 mRNA. Translation: AAL36228.1.
AY091232 mRNA. Translation: AAM14171.1.
AY086787 mRNA. Translation: AAM63837.1.
PIRiF84543.
RefSeqiNP_565391.1. NM_127226.3.
UniGeneiAt.27409.

Genome annotation databases

EnsemblPlantsiAT2G16740.1; AT2G16740.1; AT2G16740.
GeneIDi816175.
GrameneiAT2G16740.1; AT2G16740.1; AT2G16740.
KEGGiath:AT2G16740.

Cross-referencesi

Web resourcesi

PlantsUBQ

A functional genomics database for the ubiquitin/26S proteasome proteolytic pathway in plants

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ027042 mRNA. Translation: AAY44868.1.
AC005825 Genomic DNA. Translation: AAD24607.1.
CP002685 Genomic DNA. Translation: AEC06533.1.
AY063872 mRNA. Translation: AAL36228.1.
AY091232 mRNA. Translation: AAM14171.1.
AY086787 mRNA. Translation: AAM63837.1.
PIRiF84543.
RefSeqiNP_565391.1. NM_127226.3.
UniGeneiAt.27409.

3D structure databases

ProteinModelPortaliQ9SLE4.
SMRiQ9SLE4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi1532. 13 interactors.
IntActiQ9SLE4. 10 interactors.
STRINGi3702.AT2G16740.1.

Proteomic databases

PaxDbiQ9SLE4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G16740.1; AT2G16740.1; AT2G16740.
GeneIDi816175.
GrameneiAT2G16740.1; AT2G16740.1; AT2G16740.
KEGGiath:AT2G16740.

Organism-specific databases

TAIRiAT2G16740.

Phylogenomic databases

eggNOGiKOG0417. Eukaryota.
COG5078. LUCA.
HOGENOMiHOG000233455.
InParanoidiQ9SLE4.
KOiK06689.
OMAiTGEDMFH.
OrthoDBiEOG0936177B.
PhylomeDBiQ9SLE4.

Enzyme and pathway databases

UniPathwayiUPA00143.
ReactomeiR-ATH-174184. Cdc20:Phospho-APC/C mediated degradation of Cyclin A.
R-ATH-179409. APC-Cdc20 mediated degradation of Nek2A.
R-ATH-5689896. Ovarian tumor domain proteases.
R-ATH-8866652. Synthesis of active ubiquitin: roles of E1 and E2 enzymes.

Miscellaneous databases

PROiQ9SLE4.

Gene expression databases

GenevisibleiQ9SLE4. AT.

Family and domain databases

Gene3Di3.10.110.10. 1 hit.
InterProiIPR000608. UBQ-conjugat_E2.
IPR023313. UBQ-conjugating_AS.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view]
PfamiPF00179. UQ_con. 1 hit.
[Graphical view]
SUPFAMiSSF54495. SSF54495. 1 hit.
PROSITEiPS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiUBC29_ARATH
AccessioniPrimary (citable) accession number: Q9SLE4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: May 1, 2000
Last modified: November 30, 2016
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.