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Protein

Ubiquitin-conjugating enzyme E2 29

Gene

UBC29

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.

Catalytic activityi

S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.PROSITE-ProRule annotation

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.PROSITE-ProRule annotation
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei85Glycyl thioester intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • ubiquitin-protein transferase activity Source: TAIR

GO - Biological processi

  • ubiquitin-dependent protein catabolic process Source: TAIR

Keywordsi

Molecular functionTransferase
Biological processUbl conjugation pathway
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-ATH-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A
R-ATH-5689896 Ovarian tumor domain proteases
R-ATH-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes
R-ATH-8866654 E3 ubiquitin ligases ubiquitinate target proteins
R-ATH-983168 Antigen processing: Ubiquitination & Proteasome degradation
UniPathwayiUPA00143

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquitin-conjugating enzyme E2 29 (EC:2.3.2.23)
Alternative name(s):
E2 ubiquitin-conjugating enzyme 29
Ubiquitin carrier protein 29
Gene namesi
Name:UBC29
Ordered Locus Names:At2g16740
ORF Names:T24I21.15
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G16740
TAIRilocus:2059904 AT2G16740

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003451941 – 148Ubiquitin-conjugating enzyme E2 29Add BLAST148

Proteomic databases

PaxDbiQ9SLE4

Expressioni

Gene expression databases

ExpressionAtlasiQ9SLE4 baseline and differential
GenevisibleiQ9SLE4 AT

Interactioni

Protein-protein interaction databases

BioGridi153213 interactors.
IntActiQ9SLE4 10 interactors.
STRINGi3702.AT2G16740.1

Structurei

3D structure databases

ProteinModelPortaliQ9SLE4
SMRiQ9SLE4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ubiquitin-conjugating enzyme family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0417 Eukaryota
COG5078 LUCA
HOGENOMiHOG000233455
InParanoidiQ9SLE4
KOiK06689
OMAiLAQEWTT
OrthoDBiEOG0936177B
PhylomeDBiQ9SLE4

Family and domain databases

CDDicd00195 UBCc, 1 hit
Gene3Di3.10.110.101 hit
InterProiView protein in InterPro
IPR000608 UBQ-conjugat_E2
IPR023313 UBQ-conjugating_AS
IPR016135 UBQ-conjugating_enzyme/RWD
PfamiView protein in Pfam
PF00179 UQ_con, 1 hit
SUPFAMiSSF54495 SSF54495, 1 hit
PROSITEiView protein in PROSITE
PS00183 UBIQUITIN_CONJUGAT_1, 1 hit
PS50127 UBIQUITIN_CONJUGAT_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9SLE4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATRRILKEL KELQRDPPVS CSAGPTGEDM FHWQATIMGP NESPYSGGVF
60 70 80 90 100
LVNIHFPPDY PFKPPKVVFR TKVFHPNINS NGNICLDILK DQWSPALTIS
110 120 130 140
KVLLSICSLL TDPNPDDPLV PEIAHIYKTD KTKYEAMARS WTQKYALF
Length:148
Mass (Da):16,759
Last modified:May 1, 2000 - v1
Checksum:i2A1836C152DC2C12
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ027042 mRNA Translation: AAY44868.1
AC005825 Genomic DNA Translation: AAD24607.1
CP002685 Genomic DNA Translation: AEC06533.1
AY063872 mRNA Translation: AAL36228.1
AY091232 mRNA Translation: AAM14171.1
AY086787 mRNA Translation: AAM63837.1
PIRiF84543
RefSeqiNP_565391.1, NM_127226.3
UniGeneiAt.27409

Genome annotation databases

EnsemblPlantsiAT2G16740.1; AT2G16740.1; AT2G16740
GeneIDi816175
GrameneiAT2G16740.1; AT2G16740.1; AT2G16740
KEGGiath:AT2G16740

Similar proteinsi

Entry informationi

Entry nameiUBC29_ARATH
AccessioniPrimary (citable) accession number: Q9SLE4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: May 1, 2000
Last modified: April 25, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome