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Protein

Probable CCR4-associated factor 1 homolog 7

Gene

CAF1-7

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Ubiquitous transcription factor required for a diverse set of processes. It is a component of the CCR4 complex involved in the control of gene expression (By similarity).By similarity

Catalytic activityi

Exonucleolytic cleavage of poly(A) to 5'-AMP.

Cofactori

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi40 – 401Divalent metal cation; catalyticBy similarity
Metal bindingi42 – 421Divalent metal cation; catalyticBy similarity
Metal bindingi167 – 1671Divalent metal cation; catalyticBy similarity
Metal bindingi236 – 2361Divalent metal cation; catalyticBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Exonuclease, Hydrolase, Nuclease

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

Metal-binding, RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable CCR4-associated factor 1 homolog 7 (EC:3.1.13.4)
Gene namesi
Name:CAF1-7
Ordered Locus Names:At2g32070
ORF Names:F22D22.18
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G32070.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 275274Probable CCR4-associated factor 1 homolog 7PRO_0000371557Add
BLAST

Proteomic databases

PaxDbiQ9SKZ2.
PRIDEiQ9SKZ2.

Expressioni

Gene expression databases

GenevisibleiQ9SKZ2. AT.

Interactioni

Subunit structurei

Component of the CCR4-NOT complex, at least composed of CRR4 and CAF1 proteins.By similarity

Protein-protein interaction databases

STRINGi3702.AT2G32070.1.

Structurei

3D structure databases

ProteinModelPortaliQ9SKZ2.
SMRiQ9SKZ2. Positions 11-271.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CAF1 family.Curated

Phylogenomic databases

eggNOGiKOG0304. Eukaryota.
COG5228. LUCA.
HOGENOMiHOG000173077.
InParanoidiQ9SKZ2.
KOiK12581.
OMAiRIRHVIR.
OrthoDBiEOG09360HD6.
PhylomeDBiQ9SKZ2.

Family and domain databases

Gene3Di3.30.420.10. 1 hit.
InterProiIPR006941. RNase_CAF1.
IPR012337. RNaseH-like_dom.
[Graphical view]
PfamiPF04857. CAF1. 2 hits.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9SKZ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLFLKDDSI QIREVWNDNL ESEMALIREV VDDFPFVAMD TEFPGIVCRP
60 70 80 90 100
VGTFKTNTEY HYETLKTNVN ILKMIQLGLT FSDEKGNLPT CGTDNKYCIW
110 120 130 140 150
QFNFREFDLE SDIYATDSIE LLRQSGIDFV KNNEFGIDSK RFAELLMSSG
160 170 180 190 200
IVLNENVHWV TFHSGYDFGY LLKLLTCQNL PETQTGFFEM ISVYFPRVYD
210 220 230 240 250
IKHLMKFCNS LHGGLNKLAE LLDVERVGIC HQAGSDSLLT SCTFRKLQEN
260 270
FFIGSMEKYS GVLYGLGVEN GQIVH
Length:275
Mass (Da):31,543
Last modified:June 1, 2002 - v2
Checksum:i320745CB578F35B0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006223 Genomic DNA. Translation: AAD15397.2.
CP002685 Genomic DNA. Translation: AEC08630.1.
AY050946 mRNA. Translation: AAK93623.1.
AY142584 mRNA. Translation: AAN13153.1.
PIRiF84728.
RefSeqiNP_565735.1. NM_128767.3.
UniGeneiAt.22347.

Genome annotation databases

EnsemblPlantsiAT2G32070.1; AT2G32070.1; AT2G32070.
GeneIDi817767.
GrameneiAT2G32070.1; AT2G32070.1; AT2G32070.
KEGGiath:AT2G32070.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006223 Genomic DNA. Translation: AAD15397.2.
CP002685 Genomic DNA. Translation: AEC08630.1.
AY050946 mRNA. Translation: AAK93623.1.
AY142584 mRNA. Translation: AAN13153.1.
PIRiF84728.
RefSeqiNP_565735.1. NM_128767.3.
UniGeneiAt.22347.

3D structure databases

ProteinModelPortaliQ9SKZ2.
SMRiQ9SKZ2. Positions 11-271.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT2G32070.1.

Proteomic databases

PaxDbiQ9SKZ2.
PRIDEiQ9SKZ2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G32070.1; AT2G32070.1; AT2G32070.
GeneIDi817767.
GrameneiAT2G32070.1; AT2G32070.1; AT2G32070.
KEGGiath:AT2G32070.

Organism-specific databases

TAIRiAT2G32070.

Phylogenomic databases

eggNOGiKOG0304. Eukaryota.
COG5228. LUCA.
HOGENOMiHOG000173077.
InParanoidiQ9SKZ2.
KOiK12581.
OMAiRIRHVIR.
OrthoDBiEOG09360HD6.
PhylomeDBiQ9SKZ2.

Miscellaneous databases

PROiQ9SKZ2.

Gene expression databases

GenevisibleiQ9SKZ2. AT.

Family and domain databases

Gene3Di3.30.420.10. 1 hit.
InterProiIPR006941. RNase_CAF1.
IPR012337. RNaseH-like_dom.
[Graphical view]
PfamiPF04857. CAF1. 2 hits.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCAF1G_ARATH
AccessioniPrimary (citable) accession number: Q9SKZ2
Secondary accession number(s): Q949R6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: June 1, 2002
Last modified: September 7, 2016
This is version 99 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.