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Protein

Probable CCR4-associated factor 1 homolog 7

Gene

CAF1-7

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Ubiquitous transcription factor required for a diverse set of processes. It is a component of the CCR4 complex involved in the control of gene expression (By similarity).By similarity

Catalytic activityi

Exonucleolytic cleavage of poly(A) to 5'-AMP.

Cofactori

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi40Divalent metal cation; catalyticBy similarity1
Metal bindingi42Divalent metal cation; catalyticBy similarity1
Metal bindingi167Divalent metal cation; catalyticBy similarity1
Metal bindingi236Divalent metal cation; catalyticBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExonuclease, Hydrolase, Nuclease, RNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable CCR4-associated factor 1 homolog 7 (EC:3.1.13.4)
Gene namesi
Name:CAF1-7
Ordered Locus Names:At2g32070
ORF Names:F22D22.18
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G32070
TAIRilocus:2045512 AT2G32070

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003715571 – 275Probable CCR4-associated factor 1 homolog 7Add BLAST275

Proteomic databases

PaxDbiQ9SKZ2
PRIDEiQ9SKZ2

Expressioni

Gene expression databases

ExpressionAtlasiQ9SKZ2 baseline and differential
GenevisibleiQ9SKZ2 AT

Interactioni

Subunit structurei

Component of the CCR4-NOT complex, at least composed of CRR4 and CAF1 proteins.By similarity

Protein-protein interaction databases

STRINGi3702.AT2G32070.1

Structurei

3D structure databases

ProteinModelPortaliQ9SKZ2
SMRiQ9SKZ2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CAF1 family.Curated

Phylogenomic databases

eggNOGiKOG0304 Eukaryota
COG5228 LUCA
HOGENOMiHOG000173077
InParanoidiQ9SKZ2
KOiK12581
OMAiTGDVWQF
OrthoDBiEOG09360HD6
PhylomeDBiQ9SKZ2

Family and domain databases

Gene3Di3.30.420.10, 1 hit
InterProiView protein in InterPro
IPR006941 RNase_CAF1
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
PfamiView protein in Pfam
PF04857 CAF1, 2 hits
SUPFAMiSSF53098 SSF53098, 1 hit

Sequencei

Sequence statusi: Complete.

Q9SKZ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLFLKDDSI QIREVWNDNL ESEMALIREV VDDFPFVAMD TEFPGIVCRP
60 70 80 90 100
VGTFKTNTEY HYETLKTNVN ILKMIQLGLT FSDEKGNLPT CGTDNKYCIW
110 120 130 140 150
QFNFREFDLE SDIYATDSIE LLRQSGIDFV KNNEFGIDSK RFAELLMSSG
160 170 180 190 200
IVLNENVHWV TFHSGYDFGY LLKLLTCQNL PETQTGFFEM ISVYFPRVYD
210 220 230 240 250
IKHLMKFCNS LHGGLNKLAE LLDVERVGIC HQAGSDSLLT SCTFRKLQEN
260 270
FFIGSMEKYS GVLYGLGVEN GQIVH
Length:275
Mass (Da):31,543
Last modified:June 1, 2002 - v2
Checksum:i320745CB578F35B0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006223 Genomic DNA Translation: AAD15397.2
CP002685 Genomic DNA Translation: AEC08630.1
AY050946 mRNA Translation: AAK93623.1
AY142584 mRNA Translation: AAN13153.1
PIRiF84728
RefSeqiNP_565735.1, NM_128767.4
UniGeneiAt.22347

Genome annotation databases

EnsemblPlantsiAT2G32070.1; AT2G32070.1; AT2G32070
GeneIDi817767
GrameneiAT2G32070.1; AT2G32070.1; AT2G32070
KEGGiath:AT2G32070

Similar proteinsi

Entry informationi

Entry nameiCAF1G_ARATH
AccessioniPrimary (citable) accession number: Q9SKZ2
Secondary accession number(s): Q949R6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: June 1, 2002
Last modified: April 25, 2018
This is version 112 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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