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Protein

Cyclin-dependent kinases regulatory subunit 2

Gene

CKS2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-dependent kinases regulatory subunit 2
Gene namesi
Name:CKS2
Ordered Locus Names:At2g27970
ORF Names:T1E2.11
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G27970.

Subcellular locationi

GO - Cellular componenti

  • cyclin-dependent protein kinase holoenzyme complex Source: GO_Central
  • cytoplasm Source: TAIR
  • nucleus Source: TAIR
  • SCF ubiquitin ligase complex Source: GO_Central
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002940951 – 83Cyclin-dependent kinases regulatory subunit 2Add BLAST83

Proteomic databases

PaxDbiQ9SJJ5.

Expressioni

Gene expression databases

GenevisibleiQ9SJJ5. AT.

Interactioni

Subunit structurei

Interacts with CDKA-1, CYCD2-1 and AT4G14310.1 Publication

GO - Molecular functioni

Protein-protein interaction databases

BioGridi2691. 50 interactors.
IntActiQ9SJJ5. 35 interactors.
STRINGi3702.AT2G27970.1.

Structurei

3D structure databases

ProteinModelPortaliQ9SJJ5.
SMRiQ9SJJ5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CKS family.Curated

Phylogenomic databases

eggNOGiKOG3484. Eukaryota.
ENOG4111UAN. LUCA.
HOGENOMiHOG000157009.
InParanoidiQ9SJJ5.
KOiK02219.
OMAiIPKNRLM.
OrthoDBiEOG09360WQ4.
PhylomeDBiQ9SJJ5.

Family and domain databases

Gene3Di3.30.170.10. 1 hit.
InterProiIPR000789. Cyclin-dep_kinase_reg-sub.
[Graphical view]
PfamiPF01111. CKS. 1 hit.
[Graphical view]
PRINTSiPR00296. CYCLINKINASE.
SMARTiSM01084. CKS. 1 hit.
[Graphical view]
SUPFAMiSSF55637. SSF55637. 1 hit.
PROSITEiPS00944. CKS_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9SJJ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGQIQYSDKY FDDTFEYRHV VLPPEVAKLL PKNRILSESE WRAIGVQQSR
60 70 80
GWVHYAIHRP EPHIMLFRRP LNYQQEHQAQ IAK
Length:83
Mass (Da):9,987
Last modified:May 1, 2000 - v1
Checksum:i23BCACF0DEF10C03
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006929 Genomic DNA. Translation: AAD21505.1.
CP002685 Genomic DNA. Translation: AEC08065.1.
BT010784 mRNA. Translation: AAR24151.1.
BT011257 mRNA. Translation: AAR92293.1.
PIRiB84679.
RefSeqiNP_180364.1. NM_128356.6.
UniGeneiAt.38692.

Genome annotation databases

EnsemblPlantsiAT2G27970.1; AT2G27970.1; AT2G27970.
GeneIDi817341.
GrameneiAT2G27970.1; AT2G27970.1; AT2G27970.
KEGGiath:AT2G27970.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006929 Genomic DNA. Translation: AAD21505.1.
CP002685 Genomic DNA. Translation: AEC08065.1.
BT010784 mRNA. Translation: AAR24151.1.
BT011257 mRNA. Translation: AAR92293.1.
PIRiB84679.
RefSeqiNP_180364.1. NM_128356.6.
UniGeneiAt.38692.

3D structure databases

ProteinModelPortaliQ9SJJ5.
SMRiQ9SJJ5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi2691. 50 interactors.
IntActiQ9SJJ5. 35 interactors.
STRINGi3702.AT2G27970.1.

Proteomic databases

PaxDbiQ9SJJ5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G27970.1; AT2G27970.1; AT2G27970.
GeneIDi817341.
GrameneiAT2G27970.1; AT2G27970.1; AT2G27970.
KEGGiath:AT2G27970.

Organism-specific databases

TAIRiAT2G27970.

Phylogenomic databases

eggNOGiKOG3484. Eukaryota.
ENOG4111UAN. LUCA.
HOGENOMiHOG000157009.
InParanoidiQ9SJJ5.
KOiK02219.
OMAiIPKNRLM.
OrthoDBiEOG09360WQ4.
PhylomeDBiQ9SJJ5.

Miscellaneous databases

PROiQ9SJJ5.

Gene expression databases

GenevisibleiQ9SJJ5. AT.

Family and domain databases

Gene3Di3.30.170.10. 1 hit.
InterProiIPR000789. Cyclin-dep_kinase_reg-sub.
[Graphical view]
PfamiPF01111. CKS. 1 hit.
[Graphical view]
PRINTSiPR00296. CYCLINKINASE.
SMARTiSM01084. CKS. 1 hit.
[Graphical view]
SUPFAMiSSF55637. SSF55637. 1 hit.
PROSITEiPS00944. CKS_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCKS2_ARATH
AccessioniPrimary (citable) accession number: Q9SJJ5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: May 1, 2000
Last modified: November 30, 2016
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.