Q9SJJ5 (CKS2_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cyclin-dependent kinases regulatory subunit 2

Gene names

Name:	CKS2
Ordered Locus Names:	At2g27970
ORF Names:	T1E2.11

Organism

Arabidopsis thaliana (Mouse-ear cress) [Reference proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	83 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function By similarity.
Sequence similarities	Belongs to the CKS family.

Ontologies

Keywords
Biological process	Cell cycle Cell division
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell cycle Inferred from electronic annotation. Source: UniProtKB-KW cell division Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	cytoplasm Inferred from direct assay PubMed 20018602. Source: TAIR nucleus Inferred from direct assay PubMed 20018602. Source: TAIR
Molecular_function	cyclin-dependent protein serine/threonine kinase regulator activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 83	83	Cyclin-dependent kinases regulatory subunit 2		PRO_0000294095

Sequences

	Sequence		Length	Mass (Da)
	Q9SJJ5 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 23BCACF0DEF10C03	FASTA	83	9,987
	10 20 30 40 50 60 MGQIQYSDKY FDDTFEYRHV VLPPEVAKLL PKNRILSESE WRAIGVQQSR GWVHYAIHRP 70 80 EPHIMLFRRP LNYQQEHQAQ IAK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana." Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C. Nature 402:761-768(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	Cheuk R.F., Chen H., Kim C.J., Shinn P., Ecker J.R. Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[4]	"Genome-wide analysis of core cell cycle genes in Arabidopsis." Vandepoele K., Raes J., de Veylder L., Rouze P., Rombauts S., Inze D. Plant Cell 14:903-916(2002) [PubMed] [Europe PMC] [Abstract] Cited for: GENE FAMILY, NOMENCLATURE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC006929 Genomic DNA. Translation: AAD21505.1. CP002685 Genomic DNA. Translation: AEC08065.1. BT010784 mRNA. Translation: AAR24151.1. BT011257 mRNA. Translation: AAR92293.1.
IPI	IPI00525405.
PIR	B84679.
RefSeq	NP_180364.1. NM_128356.5.
UniGene	At.38692.
3D structure databases
HSSP	HSSP built from PDB template 2AST based on UniProtKB P61024.
ProteinModelPortal	Q9SJJ5.
SMR	Q9SJJ5. Positions 3-71.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9SJJ5. 35 interactions.
STRING	3702.AT2G27970.1-P.
Proteomic databases
PaxDb	Q9SJJ5.
PRIDE	Q9SJJ5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT2G27970.1; AT2G27970.1; AT2G27970.
GeneID	817341.
KEGG	ath:AT2G27970.
Organism-specific databases
GeneFarm	3299. 116.
TAIR	At2g27970.
Phylogenomic databases
eggNOG	NOG272189.
HOGENOM	HOG000157009.
InParanoid	Q9SJJ5.
KO	K02219.
OMA	DEQYEYR.
PhylomeDB	Q9SJJ5.
ProtClustDB	PLN00010.
Gene expression databases
Genevestigator	Q9SJJ5.
Family and domain databases
Gene3D	3.30.170.10. 1 hit.
InterPro	IPR000789. Cyclin-dep_kinase_reg-sub. [Graphical view]
Pfam	PF01111. CKS. 1 hit. [Graphical view]
PRINTS	PR00296. CYCLINKINASE.
SMART	SM01084. CKS. 1 hit. [Graphical view]
SUPFAM	SSF55637. Cyc_dep_kin_rsub. 1 hit.
PROSITE	PS00944. CKS_1. 1 hit. PS00945. CKS_2. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CKS2_ARATH

Accession

Primary (citable) accession number: Q9SJJ5

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 10, 2007
Last sequence update:	May 1, 2000
Last modified:	May 1, 2013
This is version 76 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program