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Protein

mRNA-decapping enzyme-like protein

Gene

At1g08370

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

As a component of the decapping complex, involved in the degradation of mRNAs. Essential for postembryonic development.2 Publications

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processmRNA processing

Enzyme and pathway databases

ReactomeiR-ATH-430039 mRNA decay by 5' to 3' exoribonuclease

Names & Taxonomyi

Protein namesi
Recommended name:
mRNA-decapping enzyme-like protein (EC:3.-.-.-)
Alternative name(s):
DCP1 homolog
Gene namesi
Ordered Locus Names:At1g08370
ORF Names:T27G7.7
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G08370
TAIRilocus:2201821 AT1G08370

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

Pathology & Biotechi

Disruption phenotypei

Lethal phenotype at the seedling cotyledon stage, with disorganized veins, swollen root hairs, and altered epidermal cell morphology.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001896361 – 367mRNA-decapping enzyme-like proteinAdd BLAST367

Proteomic databases

PaxDbiQ9SJF3
PRIDEiQ9SJF3

PTM databases

iPTMnetiQ9SJF3

Expressioni

Tissue specificityi

Expressed in seedlings, mostly in root tips, root hairs, and the vascular system. Also present in roots, leaves, stems, and flowers.1 Publication

Developmental stagei

Gradually accumulates during seed maturation to reached maximum levels in dry seeds. Fades progressively upon germination.1 Publication

Gene expression databases

ExpressionAtlasiQ9SJF3 baseline and differential
GenevisibleiQ9SJF3 AT

Interactioni

Subunit structurei

Homodimer. Component of the decapping complex. Interacts with DCP2 and DCP5 (PubMed:17158604, PubMed:19855049). Interacts with BCHA1 (PubMed:26133670).3 Publications

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi22598, 12 interactors
DIPiDIP-61572N
IntActiQ9SJF3, 5 interactors
MINTiQ9SJF3
STRINGi3702.AT1G08370.1

Structurei

3D structure databases

ProteinModelPortaliQ9SJF3
SMRiQ9SJF3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi212 – 333Pro-richAdd BLAST122

Sequence similaritiesi

Belongs to the DCP1 family.Curated

Phylogenomic databases

eggNOGiKOG2868 Eukaryota
ENOG410XRY6 LUCA
HOGENOMiHOG000242228
InParanoidiQ9SJF3
KOiK12611
OMAiIELSQWS
OrthoDBiEOG09360I8X
PhylomeDBiQ9SJF3

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR010334 Dcp1
IPR011993 PH-like_dom_sf
PANTHERiPTHR16290 PTHR16290, 1 hit
PfamiView protein in Pfam
PF06058 DCP1, 1 hit

Sequencei

Sequence statusi: Complete.

Q9SJF3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQNGKIIPN LDQNSTRLLN LTVLQRIDPY IEEILITAAH VTFYEFNIEL
60 70 80 90 100
SQWSRKDVEG SLFVVKRSTQ PRFQFIVMNR RNTDNLVENL LGDFEYEVQG
110 120 130 140 150
PYLLYRNASQ EVNGIWFYNK RECEEVATLF NRILSAYSKV NQKPKASSSK
160 170 180 190 200
SEFEELEAKP TMAVMDGPLE PSSTARDAPD DPAFVNFFSS TMNLGNTASG
210 220 230 240 250
SASGPYQSSA IPHQPHQPHQ PTIAPPVAAA APPQIQSPPP LQSSSPLMTL
260 270 280 290 300
FDNNPEVISS NSNIHTDLVT PSFFGPPRMM AQPHLIPGVS MPTAPPLNPN
310 320 330 340 350
NASHQQRSYG TPVLQPFPPP TPPPSLAPAP TGPVISRDKV KEALLSLLQE
360
DEFIDKITRT LQNALQQ
Length:367
Mass (Da):40,611
Last modified:June 7, 2005 - v2
Checksum:i1820226F02FEE28D
GO

Sequence cautioni

The sequence AAF22887 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti212P → PHQP in AAC17938 (Ref. 1) Curated1
Sequence conflicti293T → S in AAC17938 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF007109 mRNA Translation: AAC17938.1
AC006932 Genomic DNA Translation: AAF22887.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE28282.1
PIRiT52141
RefSeqiNP_563814.1, NM_100710.4
UniGeneiAt.24949

Genome annotation databases

EnsemblPlantsiAT1G08370.1; AT1G08370.1; AT1G08370
GeneIDi837357
GrameneiAT1G08370.1; AT1G08370.1; AT1G08370
KEGGiath:AT1G08370

Similar proteinsi

Entry informationi

Entry nameiDCP1_ARATH
AccessioniPrimary (citable) accession number: Q9SJF3
Secondary accession number(s): O64895
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: June 7, 2005
Last modified: May 23, 2018
This is version 107 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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