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Protein

Vesicle-associated membrane protein 712

Gene

VAMP712

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Involved in the targeting and/or fusion of transport vesicles to their target membrane.1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transport, Transport

Enzyme and pathway databases

ReactomeiR-ATH-8856825. Cargo recognition for clathrin-mediated endocytosis.

Names & Taxonomyi

Protein namesi
Recommended name:
Vesicle-associated membrane protein 7121 Publication
Short name:
AtVAMP7121 Publication
Gene namesi
Name:VAMP7121 Publication
Ordered Locus Names:At2g25340Imported
ORF Names:T22F11.7Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G25340.
TAIRilocus:2059591. AT2G25340.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 189CytoplasmicSequence analysisAdd BLAST189
Transmembranei190 – 210Helical; Anchor for type IV membrane proteinSequence analysisAdd BLAST21
Topological domaini211 – 219VesicularSequence analysis9

Keywords - Cellular componenti

Membrane, Vacuole

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002067511 – 219Vesicle-associated membrane protein 712Add BLAST219

Proteomic databases

PaxDbiQ9SIQ9.

Expressioni

Tissue specificityi

Expressed in flowers, leaves, stems and roots.1 Publication

Gene expression databases

ExpressionAtlasiQ9SIQ9. baseline and differential.
GenevisibleiQ9SIQ9. AT.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi3702.AT2G25340.1.

Structurei

3D structure databases

ProteinModelPortaliQ9SIQ9.
SMRiQ9SIQ9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 111LonginPROSITE-ProRule annotationAdd BLAST105
Domaini126 – 186v-SNARE coiled-coil homologyPROSITE-ProRule annotationAdd BLAST61

Domaini

The longin domain is critical for the vacuolar localization.1 Publication

Sequence similaritiesi

Belongs to the synaptobrevin family.Curated

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0859. Eukaryota.
COG5143. LUCA.
HOGENOMiHOG000042711.
InParanoidiQ9SIQ9.
KOiK08515.
OMAiCMADEDA.
OrthoDBiEOG09360NL1.
PhylomeDBiQ9SIQ9.

Family and domain databases

InterProiView protein in InterPro
IPR011012. Longin-like_dom.
IPR010908. Longin_dom.
IPR001388. Synaptobrevin.
PfamiView protein in Pfam
PF13774. Longin. 1 hit.
PF00957. Synaptobrevin. 1 hit.
PRINTSiPR00219. SYNAPTOBREVN.
SMARTiView protein in SMART
SM01270. Longin. 1 hit.
SUPFAMiSSF64356. SSF64356. 1 hit.
PROSITEiView protein in PROSITE
PS50859. LONGIN. 1 hit.
PS00417. SYNAPTOBREVIN. 1 hit.
PS50892. V_SNARE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9SIQ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSILYALVAR GTVVLAELST TSTNASTIAK QILEKIPGNG DSHVSYSQDR
60 70 80 90 100
YVFHVKRTDG LTVLCMADED AGRRIPFSFL EDIHQRFVRT YGRAIHSAQA
110 120 130 140 150
YAMNDEFSRV LNQQIEYYSN DPNADTISRI KGEMNQVRDV MIENIDNILD
160 170 180 190 200
RGERLELLVD KTANMQGNTF RFRKQTRRFN NTVWWRNCKL TLLLILVLLV
210
IIYIGVAFAC HGPTLPSCV
Length:219
Mass (Da):24,966
Last modified:May 1, 2000 - v1
Checksum:i7A63C85A140913B9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007070 Genomic DNA. Translation: AAD23657.1.
CP002685 Genomic DNA. Translation: AEC07690.1.
PIRiC84647.
RefSeqiNP_180106.1. NM_128091.1.
UniGeneiAt.52906.

Genome annotation databases

EnsemblPlantsiAT2G25340.1; AT2G25340.1; AT2G25340.
GeneIDi817072.
GrameneiAT2G25340.1; AT2G25340.1; AT2G25340.
KEGGiath:AT2G25340.

Similar proteinsi

Entry informationi

Entry nameiVA712_ARATH
AccessioniPrimary (citable) accession number: Q9SIQ9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 17, 2003
Last sequence update: May 1, 2000
Last modified: August 30, 2017
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families