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Protein

Probable glucose-1-phosphate adenylyltransferase large subunit, chloroplastic

Gene

At2g21590

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP (By similarity).By similarity

Catalytic activityi

ATP + alpha-D-glucose 1-phosphate = diphosphate + ADP-glucose.

Enzyme regulationi

Activated by 3'phosphoglycerate, inhibited by orthophosphate. Allosteric regulation (By similarity).By similarity

Pathwayi: starch biosynthesis

This protein is involved in the pathway starch biosynthesis, which is part of Glycan biosynthesis.
View all proteins of this organism that are known to be involved in the pathway starch biosynthesis and in Glycan biosynthesis.

GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • glucose-1-phosphate adenylyltransferase activity Source: TAIR

GO - Biological processi

  • glycogen biosynthetic process Source: InterPro
  • starch biosynthetic process Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Starch biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:GQT-363-MONOMER.
BRENDAi2.7.7.27. 399.
SABIO-RKQ9SIK1.
UniPathwayiUPA00152.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glucose-1-phosphate adenylyltransferase large subunit, chloroplastic (EC:2.7.7.27)
Alternative name(s):
ADP-glucose pyrophosphorylase
ADP-glucose synthase
AGPase S
Alpha-D-glucose-1-phosphate adenyl transferase
Gene namesi
Ordered Locus Names:At2g21590
ORF Names:F2G1.14
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G21590.

Subcellular locationi

GO - Cellular componenti

  • chloroplast Source: UniProtKB-SubCell
  • glucose-1-phosphate adenylyltransferase complex Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Chloroplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini? – 523Probable glucose-1-phosphate adenylyltransferase large subunit, chloroplasticPRO_0000011162
Transit peptidei1 – ?ChloroplastSequence analysis

Proteomic databases

PaxDbiQ9SIK1.
PRIDEiQ9SIK1.

PTM databases

iPTMnetiQ9SIK1.

Expressioni

Gene expression databases

ExpressionAtlasiQ9SIK1. baseline and differential.
GenevisibleiQ9SIK1. AT.

Interactioni

Subunit structurei

Heterotetramer.By similarity

Protein-protein interaction databases

BioGridi2050. 1 interaction.
IntActiQ9SIK1. 1 interaction.
STRINGi3702.AT2G21590.1.

Structurei

3D structure databases

ProteinModelPortaliQ9SIK1.
SMRiQ9SIK1. Positions 103-523.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiENOG410IMYM. Eukaryota.
COG0448. LUCA.
HOGENOMiHOG000278604.
InParanoidiQ9SIK1.
KOiK00975.
OMAiCRMVDSI.
OrthoDBiEOG093608F5.
PhylomeDBiQ9SIK1.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiIPR005836. ADP_Glu_pyroP_CS.
IPR011831. GlgC.
IPR005835. NTP_transferase_dom.
IPR029044. Nucleotide-diphossugar_trans.
IPR011004. Trimer_LpxA-like.
[Graphical view]
PfamiPF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMiSSF51161. SSF51161. 1 hit.
SSF53448. SSF53448. 2 hits.
TIGRFAMsiTIGR02091. glgC. 1 hit.
PROSITEiPS00808. ADP_GLC_PYROPHOSPH_1. 1 hit.
PS00809. ADP_GLC_PYROPHOSPH_2. 1 hit.
PS00810. ADP_GLC_PYROPHOSPH_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9SIK1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSSYSFALG TSSSILPKLS FRNVENRFYG EKNNNNGLCK RFGSDLGSKK
60 70 80 90 100
FRNQKFKHGV VYAVATSDNP KKAMTVKTSM FERRKVDPQN VAAIILGGGN
110 120 130 140 150
GAKLFPLTMR AATPAVPVGG CYRLIDIPMS NCINSCINKI FVLTQFNSAS
160 170 180 190 200
LNRHLARTYF GNGINFGGGF VEVLAATQTP GEAGKKWFQG TADAVRKFLW
210 220 230 240 250
VFEDAKNRNI ENILILSGDH LYRMNYMDFV QSHVDSNADI TLSCAPVSES
260 270 280 290 300
RASNFGLVKI DRGGRVIHFS EKPTGVDLKS MQTDTTMLGL SHQEATDSPY
310 320 330 340 350
IASMGVYCFK TEALLNLLTR QYPSSNDFGS EVIPAAIRDH DVQGYIFRDY
360 370 380 390 400
WEDIGTIKTF YEANLALVEE RPKFEFYDPE TPFYTSPRFL PPTKAEKCRM
410 420 430 440 450
VDSIISHGCF LRECSVQRSI IGERSRLDYG VELQDTLMLG ADYYQTESEI
460 470 480 490 500
ASLLAEGKVP IGIGKDTKIR KCIIDKNAKI GKNVIIMNKG DVQEADRPEE
510 520
GFYIRSGITV IVEKATIQDG TVI
Length:523
Mass (Da):58,205
Last modified:May 1, 2000 - v1
Checksum:i6A53681F86129565
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007119 Genomic DNA. Translation: AAD23646.1.
CP002685 Genomic DNA. Translation: AEC07199.1.
CP002685 Genomic DNA. Translation: AEC07200.1.
AY070429 mRNA. Translation: AAL49924.1.
AY096657 mRNA. Translation: AAM20291.1.
PIRiA84603.
RefSeqiNP_001031391.1. NM_001036314.1.
NP_179753.1. NM_127730.4.
UniGeneiAt.28357.

Genome annotation databases

EnsemblPlantsiAT2G21590.1; AT2G21590.1; AT2G21590.
AT2G21590.2; AT2G21590.2; AT2G21590.
GeneIDi816697.
GrameneiAT2G21590.1; AT2G21590.1; AT2G21590.
AT2G21590.2; AT2G21590.2; AT2G21590.
KEGGiath:AT2G21590.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007119 Genomic DNA. Translation: AAD23646.1.
CP002685 Genomic DNA. Translation: AEC07199.1.
CP002685 Genomic DNA. Translation: AEC07200.1.
AY070429 mRNA. Translation: AAL49924.1.
AY096657 mRNA. Translation: AAM20291.1.
PIRiA84603.
RefSeqiNP_001031391.1. NM_001036314.1.
NP_179753.1. NM_127730.4.
UniGeneiAt.28357.

3D structure databases

ProteinModelPortaliQ9SIK1.
SMRiQ9SIK1. Positions 103-523.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi2050. 1 interaction.
IntActiQ9SIK1. 1 interaction.
STRINGi3702.AT2G21590.1.

PTM databases

iPTMnetiQ9SIK1.

Proteomic databases

PaxDbiQ9SIK1.
PRIDEiQ9SIK1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G21590.1; AT2G21590.1; AT2G21590.
AT2G21590.2; AT2G21590.2; AT2G21590.
GeneIDi816697.
GrameneiAT2G21590.1; AT2G21590.1; AT2G21590.
AT2G21590.2; AT2G21590.2; AT2G21590.
KEGGiath:AT2G21590.

Organism-specific databases

TAIRiAT2G21590.

Phylogenomic databases

eggNOGiENOG410IMYM. Eukaryota.
COG0448. LUCA.
HOGENOMiHOG000278604.
InParanoidiQ9SIK1.
KOiK00975.
OMAiCRMVDSI.
OrthoDBiEOG093608F5.
PhylomeDBiQ9SIK1.

Enzyme and pathway databases

UniPathwayiUPA00152.
BioCyciARA:GQT-363-MONOMER.
BRENDAi2.7.7.27. 399.
SABIO-RKQ9SIK1.

Miscellaneous databases

PROiQ9SIK1.

Gene expression databases

ExpressionAtlasiQ9SIK1. baseline and differential.
GenevisibleiQ9SIK1. AT.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiIPR005836. ADP_Glu_pyroP_CS.
IPR011831. GlgC.
IPR005835. NTP_transferase_dom.
IPR029044. Nucleotide-diphossugar_trans.
IPR011004. Trimer_LpxA-like.
[Graphical view]
PfamiPF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMiSSF51161. SSF51161. 1 hit.
SSF53448. SSF53448. 2 hits.
TIGRFAMsiTIGR02091. glgC. 1 hit.
PROSITEiPS00808. ADP_GLC_PYROPHOSPH_1. 1 hit.
PS00809. ADP_GLC_PYROPHOSPH_2. 1 hit.
PS00810. ADP_GLC_PYROPHOSPH_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGLGL4_ARATH
AccessioniPrimary (citable) accession number: Q9SIK1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 2000
Last modified: September 7, 2016
This is version 122 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Allosteric enzyme, Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.