ID   PLAT2_ARATH             Reviewed;         183 AA.
AC   Q9SIE7; Q8LEG8;
DT   07-SEP-2016, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   27-MAR-2024, entry version 144.
DE   RecName: Full=PLAT domain-containing protein 2 {ECO:0000305};
DE            Short=AtPLAT2 {ECO:0000303|PubMed:25396746};
DE            Short=PLAT domain protein 2 {ECO:0000303|PubMed:25396746};
DE   Flags: Precursor;
GN   Name=PLAT2 {ECO:0000303|PubMed:25396746};
GN   OrderedLocusNames=At2g22170 {ECO:0000312|Araport:AT2G22170};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA   Feldmann K.A.;
RT   "Full-length cDNA from Arabidopsis thaliana.";
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   INDUCTION, AND DISRUPTION PHENOTYPE.
RX   PubMed=25396746; DOI=10.1371/journal.pone.0112946;
RA   Hyun T.K., van der Graaff E., Albacete A., Eom S.H., Grosskinsky D.K.,
RA   Boehm H., Janschek U., Rim Y., Ali W.W., Kim S.Y., Roitsch T.;
RT   "The Arabidopsis PLAT domain protein1 is critically involved in abiotic
RT   stress tolerance.";
RL   PLoS ONE 9:E112946-E112946(2014).
CC   -!- FUNCTION: Involved in response to abiotic stress.
CC       {ECO:0000250|UniProtKB:O65660}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum
CC       {ECO:0000250|UniProtKB:O65660}.
CC   -!- INDUCTION: Down-regulated by salt stress.
CC       {ECO:0000269|PubMed:25396746}.
CC   -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC       conditions. {ECO:0000269|PubMed:25396746}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAM62648.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AC007168; AAD23623.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC07274.1; -; Genomic_DNA.
DR   EMBL; BT002824; AAO22643.1; -; mRNA.
DR   EMBL; BT004384; AAO42378.1; -; mRNA.
DR   EMBL; AY085421; AAM62648.1; ALT_INIT; mRNA.
DR   PIR; G84609; G84609.
DR   RefSeq; NP_565527.1; NM_127785.4.
DR   AlphaFoldDB; Q9SIE7; -.
DR   SMR; Q9SIE7; -.
DR   STRING; 3702.Q9SIE7; -.
DR   PaxDb; 3702-AT2G22170-1; -.
DR   ProteomicsDB; 226200; -.
DR   EnsemblPlants; AT2G22170.1; AT2G22170.1; AT2G22170.
DR   GeneID; 816751; -.
DR   Gramene; AT2G22170.1; AT2G22170.1; AT2G22170.
DR   KEGG; ath:AT2G22170; -.
DR   Araport; AT2G22170; -.
DR   TAIR; AT2G22170; PLAT2.
DR   eggNOG; ENOG502RZE1; Eukaryota.
DR   HOGENOM; CLU_092946_0_0_1; -.
DR   InParanoid; Q9SIE7; -.
DR   OMA; PHARCSR; -.
DR   OrthoDB; 312662at2759; -.
DR   PhylomeDB; Q9SIE7; -.
DR   PRO; PR:Q9SIE7; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q9SIE7; baseline and differential.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR   GO; GO:0099503; C:secretory vesicle; HDA:TAIR.
DR   GO; GO:0009579; C:thylakoid; HDA:TAIR.
DR   GO; GO:0005773; C:vacuole; HDA:TAIR.
DR   CDD; cd01754; PLAT_plant_stress; 1.
DR   Gene3D; 2.60.60.20; PLAT/LH2 domain; 1.
DR   InterPro; IPR001024; PLAT/LH2_dom.
DR   InterPro; IPR036392; PLAT/LH2_dom_sf.
DR   PANTHER; PTHR31718; PLAT DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR31718:SF0; PLAT DOMAIN-CONTAINING PROTEIN 2; 1.
DR   Pfam; PF01477; PLAT; 1.
DR   SUPFAM; SSF49723; Lipase/lipooxygenase domain (PLAT/LH2 domain); 1.
DR   PROSITE; PS50095; PLAT; 1.
PE   2: Evidence at transcript level;
KW   Endoplasmic reticulum; Reference proteome; Signal; Stress response.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..183
FT                   /note="PLAT domain-containing protein 2"
FT                   /id="PRO_5006752344"
FT   DOMAIN          31..158
FT                   /note="PLAT"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00152"
FT   CONFLICT        36
FT                   /note="F -> Y (in Ref. 4; AAM62648)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   183 AA;  20130 MW;  B0322292368BB92D CRC64;
     MMPRRDVLFL SLLLVIATVS AVALADDEAD CVYTFFLRTG STFKAGTDSI ISARVYDKYG
     DYIGIRNLEA WGGLMGPGYN YYERGNLDIF SGKAPCLPSP VCSLNLTSDG SGDHHGWYVN
     YVEVTTAGVH AKCSYQSFDV EQWLASDTSP YELSAVRNNC PVSLRESVGR VGSEIRKTLS
     WIV
//