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Protein

Purple acid phosphatase 11

Gene

PAP11

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.

Cofactori

Protein has several cofactor binding sites:
  • Fe cationBy similarityNote: Binds 1 Fe cation per subunit.By similarity
  • Zn2+By similarityNote: Binds 1 zinc ion per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi145IronBy similarity1
Metal bindingi173IronBy similarity1
Metal bindingi173ZincBy similarity1
Metal bindingi176IronBy similarity1
Metal bindingi210ZincBy similarity1
Binding sitei210SubstrateBy similarity1
Metal bindingi295ZincBy similarity1
Active sitei305Proton donorBy similarity1
Metal bindingi332ZincBy similarity1
Metal bindingi334IronBy similarity1

GO - Molecular functioni

  • acid phosphatase activity Source: TAIR
  • metal ion binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Iron, Metal-binding, Zinc

Enzyme and pathway databases

BioCyciARA:AT2G18130-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Purple acid phosphatase 11 (EC:3.1.3.2)
Gene namesi
Name:PAP11
Synonyms:AT8
Ordered Locus Names:At2g18130
ORF Names:F8D23.9
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G18130.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_000037281625 – 441Purple acid phosphatase 11Add BLAST417

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi111N-linked (GlcNAc...)Sequence analysis1
Glycosylationi153N-linked (GlcNAc...)Sequence analysis1
Glycosylationi283N-linked (GlcNAc...)Sequence analysis1
Glycosylationi348N-linked (GlcNAc...)Sequence analysis1
Glycosylationi405N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ9SI18.

PTM databases

iPTMnetiQ9SI18.

Expressioni

Tissue specificityi

Specifically expressed in flowers.1 Publication

Inductioni

By phosphate deprivation.1 Publication

Gene expression databases

GenevisibleiQ9SI18. AT.

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi3702.AT2G18130.1.

Structurei

3D structure databases

ProteinModelPortaliQ9SI18.
SMRiQ9SI18.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni332 – 334Substrate bindingBy similarity3

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG1378. Eukaryota.
COG1409. LUCA.
HOGENOMiHOG000238330.
InParanoidiQ9SI18.
OMAiRAMIISW.
OrthoDBiEOG09360APJ.
PhylomeDBiQ9SI18.

Family and domain databases

Gene3Di2.60.40.380. 1 hit.
3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_ApaH.
IPR029052. Metallo-depent_PP-like.
IPR008963. Purple_acid_Pase-like_N.
IPR015914. Purple_acid_Pase_N.
IPR025733. Purple_acid_PPase_C_dom.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
PF14008. Metallophos_C. 1 hit.
PF16656. Pur_ac_phosph_N. 1 hit.
[Graphical view]
SUPFAMiSSF49363. SSF49363. 1 hit.
SSF56300. SSF56300. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9SI18-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELSHLALVC AAIAFSSIFV VSQAGITSTH ARVSEPSEEM SLETFPPPAG
60 70 80 90 100
YNAPEQVHIT QGDNAGRAMI ISWVMPLNED GSNVVTYWIA SSDGSDNKNA
110 120 130 140 150
IATTSSYRYF NYTSGYLHHA TIKKLEYDPS KSRSRCSLHI RYYSDLGQTY
160 170 180 190 200
ASNQTLYNYM SNPKGQAVLF VGDLSYADDH PNHDQRKWDS YGRFVEPSAA
210 220 230 240 250
YQPWSWAAGN YEIDYAQSIS ETQPFKPYKN RYHVPYKASQ STSPLWYSIK
260 270 280 290 300
RASTYIIVLS SYSAYDKYTP QNSWLQDELK KVNRSETSWL IVLVHAPWYN
310 320 330 340 350
SNNYHYMEGE SMRVTFEPWF VENKVDIVFA GHVHAYERSK RISNIHYNIT
360 370 380 390 400
DGMSTPVKDQ NAPIYITIGD GGNIEGIANS FTDPQPSYSA FREASFGHAL
410 420 430 440
LEIKNRTHAH YTWHRNKEDE AVIADSIWLK KRYYLPEEET A
Length:441
Mass (Da):50,362
Last modified:May 1, 2000 - v1
Checksum:i861E402A9A936424
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti319W → M in AAP81218 (Ref. 5) Curated1
Sequence conflicti324K → I in AAP81218 (Ref. 5) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF492663 mRNA. Translation: AAM15912.1.
AC007212 Genomic DNA. Translation: AAD31353.1.
CP002685 Genomic DNA. Translation: AEC06729.1.
BT026132 mRNA. Translation: ABG48488.1.
AY297745 mRNA. Translation: AAP81218.1.
PIRiF84560.
RefSeqiNP_179405.1. NM_127370.1.
UniGeneiAt.40038.

Genome annotation databases

EnsemblPlantsiAT2G18130.1; AT2G18130.1; AT2G18130.
GeneIDi816326.
GrameneiAT2G18130.1; AT2G18130.1; AT2G18130.
KEGGiath:AT2G18130.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF492663 mRNA. Translation: AAM15912.1.
AC007212 Genomic DNA. Translation: AAD31353.1.
CP002685 Genomic DNA. Translation: AEC06729.1.
BT026132 mRNA. Translation: ABG48488.1.
AY297745 mRNA. Translation: AAP81218.1.
PIRiF84560.
RefSeqiNP_179405.1. NM_127370.1.
UniGeneiAt.40038.

3D structure databases

ProteinModelPortaliQ9SI18.
SMRiQ9SI18.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT2G18130.1.

PTM databases

iPTMnetiQ9SI18.

Proteomic databases

PaxDbiQ9SI18.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G18130.1; AT2G18130.1; AT2G18130.
GeneIDi816326.
GrameneiAT2G18130.1; AT2G18130.1; AT2G18130.
KEGGiath:AT2G18130.

Organism-specific databases

TAIRiAT2G18130.

Phylogenomic databases

eggNOGiKOG1378. Eukaryota.
COG1409. LUCA.
HOGENOMiHOG000238330.
InParanoidiQ9SI18.
OMAiRAMIISW.
OrthoDBiEOG09360APJ.
PhylomeDBiQ9SI18.

Enzyme and pathway databases

BioCyciARA:AT2G18130-MONOMER.

Miscellaneous databases

PROiQ9SI18.

Gene expression databases

GenevisibleiQ9SI18. AT.

Family and domain databases

Gene3Di2.60.40.380. 1 hit.
3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_ApaH.
IPR029052. Metallo-depent_PP-like.
IPR008963. Purple_acid_Pase-like_N.
IPR015914. Purple_acid_Pase_N.
IPR025733. Purple_acid_PPase_C_dom.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
PF14008. Metallophos_C. 1 hit.
PF16656. Pur_ac_phosph_N. 1 hit.
[Graphical view]
SUPFAMiSSF49363. SSF49363. 1 hit.
SSF56300. SSF56300. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPPA11_ARATH
AccessioniPrimary (citable) accession number: Q9SI18
Secondary accession number(s): Q7XY10
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: May 1, 2000
Last modified: November 30, 2016
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.