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Q9SI18

- PPA11_ARATH

UniProt

Q9SI18 - PPA11_ARATH

Protein

Purple acid phosphatase 11

Gene

PAP11

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 87 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    A phosphate monoester + H2O = an alcohol + phosphate.

    Cofactori

    Binds 1 iron ion per subunit.By similarity
    Binds 1 zinc ion per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi145 – 1451IronBy similarity
    Metal bindingi173 – 1731IronBy similarity
    Metal bindingi173 – 1731ZincBy similarity
    Metal bindingi176 – 1761IronBy similarity
    Metal bindingi210 – 2101ZincBy similarity
    Binding sitei210 – 2101SubstrateBy similarity
    Metal bindingi295 – 2951ZincBy similarity
    Active sitei305 – 3051Proton donorBy similarity
    Metal bindingi332 – 3321ZincBy similarity
    Metal bindingi334 – 3341IronBy similarity

    GO - Molecular functioni

    1. acid phosphatase activity Source: TAIR
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. dephosphorylation Source: GOC

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Ligandi

    Iron, Metal-binding, Zinc

    Enzyme and pathway databases

    BioCyciARA:AT2G18130-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Purple acid phosphatase 11 (EC:3.1.3.2)
    Gene namesi
    Name:PAP11
    Synonyms:AT8
    Ordered Locus Names:At2g18130
    ORF Names:F8D23.9
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 2

    Organism-specific databases

    TAIRiAT2G18130.

    Subcellular locationi

    Secreted By similarity

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2424Sequence AnalysisAdd
    BLAST
    Chaini25 – 441417Purple acid phosphatase 11PRO_0000372816Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi111 – 1111N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi153 – 1531N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi283 – 2831N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi348 – 3481N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi405 – 4051N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Expressioni

    Tissue specificityi

    Specifically expressed in flowers.1 Publication

    Inductioni

    By phosphate deprivation.1 Publication

    Gene expression databases

    GenevestigatoriQ9SI18.

    Interactioni

    Subunit structurei

    Homodimer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ9SI18.
    SMRiQ9SI18. Positions 43-439.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni332 – 3343Substrate bindingBy similarity

    Sequence similaritiesi

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiCOG1409.
    HOGENOMiHOG000238330.
    InParanoidiQ9SI18.
    OMAiNTEGIAN.
    PhylomeDBiQ9SI18.

    Family and domain databases

    Gene3Di2.60.40.380. 1 hit.
    3.60.21.10. 1 hit.
    InterProiIPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    IPR008963. Purple_acid_Pase-like_N.
    IPR015914. Purple_acid_Pase_N.
    IPR025733. Purple_acid_PPase_C_dom.
    [Graphical view]
    PfamiPF00149. Metallophos. 1 hit.
    PF14008. Metallophos_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF49363. SSF49363. 1 hit.
    SSF56300. SSF56300. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q9SI18-1 [UniParc]FASTAAdd to Basket

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    MELSHLALVC AAIAFSSIFV VSQAGITSTH ARVSEPSEEM SLETFPPPAG    50
    YNAPEQVHIT QGDNAGRAMI ISWVMPLNED GSNVVTYWIA SSDGSDNKNA 100
    IATTSSYRYF NYTSGYLHHA TIKKLEYDPS KSRSRCSLHI RYYSDLGQTY 150
    ASNQTLYNYM SNPKGQAVLF VGDLSYADDH PNHDQRKWDS YGRFVEPSAA 200
    YQPWSWAAGN YEIDYAQSIS ETQPFKPYKN RYHVPYKASQ STSPLWYSIK 250
    RASTYIIVLS SYSAYDKYTP QNSWLQDELK KVNRSETSWL IVLVHAPWYN 300
    SNNYHYMEGE SMRVTFEPWF VENKVDIVFA GHVHAYERSK RISNIHYNIT 350
    DGMSTPVKDQ NAPIYITIGD GGNIEGIANS FTDPQPSYSA FREASFGHAL 400
    LEIKNRTHAH YTWHRNKEDE AVIADSIWLK KRYYLPEEET A 441
    Length:441
    Mass (Da):50,362
    Last modified:May 1, 2000 - v1
    Checksum:i861E402A9A936424
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti319 – 3191W → M in AAP81218. 1 PublicationCurated
    Sequence conflicti324 – 3241K → I in AAP81218. 1 PublicationCurated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF492663 mRNA. Translation: AAM15912.1.
    AC007212 Genomic DNA. Translation: AAD31353.1.
    CP002685 Genomic DNA. Translation: AEC06729.1.
    BT026132 mRNA. Translation: ABG48488.1.
    AY297745 mRNA. Translation: AAP81218.1.
    PIRiF84560.
    RefSeqiNP_179405.1. NM_127370.1.
    UniGeneiAt.40038.

    Genome annotation databases

    EnsemblPlantsiAT2G18130.1; AT2G18130.1; AT2G18130.
    GeneIDi816326.
    KEGGiath:AT2G18130.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF492663 mRNA. Translation: AAM15912.1 .
    AC007212 Genomic DNA. Translation: AAD31353.1 .
    CP002685 Genomic DNA. Translation: AEC06729.1 .
    BT026132 mRNA. Translation: ABG48488.1 .
    AY297745 mRNA. Translation: AAP81218.1 .
    PIRi F84560.
    RefSeqi NP_179405.1. NM_127370.1.
    UniGenei At.40038.

    3D structure databases

    ProteinModelPortali Q9SI18.
    SMRi Q9SI18. Positions 43-439.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT2G18130.1 ; AT2G18130.1 ; AT2G18130 .
    GeneIDi 816326.
    KEGGi ath:AT2G18130.

    Organism-specific databases

    TAIRi AT2G18130.

    Phylogenomic databases

    eggNOGi COG1409.
    HOGENOMi HOG000238330.
    InParanoidi Q9SI18.
    OMAi NTEGIAN.
    PhylomeDBi Q9SI18.

    Enzyme and pathway databases

    BioCyci ARA:AT2G18130-MONOMER.

    Gene expression databases

    Genevestigatori Q9SI18.

    Family and domain databases

    Gene3Di 2.60.40.380. 1 hit.
    3.60.21.10. 1 hit.
    InterProi IPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    IPR008963. Purple_acid_Pase-like_N.
    IPR015914. Purple_acid_Pase_N.
    IPR025733. Purple_acid_PPase_C_dom.
    [Graphical view ]
    Pfami PF00149. Metallophos. 1 hit.
    PF14008. Metallophos_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49363. SSF49363. 1 hit.
    SSF56300. SSF56300. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Purple acid phosphatases of Arabidopsis thaliana. Comparative analysis and differential regulation by phosphate deprivation."
      Li D., Zhu H., Liu K., Liu X., Leggewie G., Udvardi M., Wang D.
      J. Biol. Chem. 277:27772-27781(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], INDUCTION, GENE FAMILY, NOMENCLATURE.
      Strain: cv. Col-1.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    3. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    4. "Arabidopsis ORF clones."
      Kim C.J., Chen H., Quinitio C., Shinn P., Ecker J.R.
      Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    5. "Identification of differentially displayed Arabidopsis thaliana acid phosphatase-encoding genes."
      Lohrasebi T., Malboobi M.A.
      Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 241-400.
      Tissue: Seedling.
    6. "Expression patterns of purple acid phosphatase genes in Arabidopsis organs and functional analysis of AtPAP23 predominantly transcribed in flower."
      Zhu H., Qian W., Lu X., Li D., Liu X., Liu K., Wang D.
      Plant Mol. Biol. 59:581-594(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: TISSUE SPECIFICITY.

    Entry informationi

    Entry nameiPPA11_ARATH
    AccessioniPrimary (citable) accession number: Q9SI18
    Secondary accession number(s): Q7XY10
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 5, 2009
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 87 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3