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Q9SI18

- PPA11_ARATH

UniProt

Q9SI18 - PPA11_ARATH

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Protein

Purple acid phosphatase 11

Gene

PAP11

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.

Cofactori

Protein has several cofactor binding sites:
  • Fe cationBy similarityNote: Binds 1 Fe cation per subunit.By similarity
  • Zn2+By similarityNote: Binds 1 zinc ion per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi145 – 1451IronBy similarity
Metal bindingi173 – 1731IronBy similarity
Metal bindingi173 – 1731ZincBy similarity
Metal bindingi176 – 1761IronBy similarity
Metal bindingi210 – 2101ZincBy similarity
Binding sitei210 – 2101SubstrateBy similarity
Metal bindingi295 – 2951ZincBy similarity
Active sitei305 – 3051Proton donorBy similarity
Metal bindingi332 – 3321ZincBy similarity
Metal bindingi334 – 3341IronBy similarity

GO - Molecular functioni

  1. acid phosphatase activity Source: TAIR
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. dephosphorylation Source: GOC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Iron, Metal-binding, Zinc

Enzyme and pathway databases

BioCyciARA:AT2G18130-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Purple acid phosphatase 11 (EC:3.1.3.2)
Gene namesi
Name:PAP11
Synonyms:AT8
Ordered Locus Names:At2g18130
ORF Names:F8D23.9
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 2

Organism-specific databases

TAIRiAT2G18130.

Subcellular locationi

Secreted By similarity

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2424Sequence AnalysisAdd
BLAST
Chaini25 – 441417Purple acid phosphatase 11PRO_0000372816Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi111 – 1111N-linked (GlcNAc...)Sequence Analysis
Glycosylationi153 – 1531N-linked (GlcNAc...)Sequence Analysis
Glycosylationi283 – 2831N-linked (GlcNAc...)Sequence Analysis
Glycosylationi348 – 3481N-linked (GlcNAc...)Sequence Analysis
Glycosylationi405 – 4051N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Expressioni

Tissue specificityi

Specifically expressed in flowers.1 Publication

Inductioni

By phosphate deprivation.1 Publication

Gene expression databases

GenevestigatoriQ9SI18.

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ9SI18.
SMRiQ9SI18. Positions 43-439.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni332 – 3343Substrate bindingBy similarity

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG1409.
HOGENOMiHOG000238330.
InParanoidiQ9SI18.
OMAiNTEGIAN.
PhylomeDBiQ9SI18.

Family and domain databases

Gene3Di2.60.40.380. 1 hit.
3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR008963. Purple_acid_Pase-like_N.
IPR015914. Purple_acid_Pase_N.
IPR025733. Purple_acid_PPase_C_dom.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
PF14008. Metallophos_C. 1 hit.
[Graphical view]
SUPFAMiSSF49363. SSF49363. 1 hit.
SSF56300. SSF56300. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9SI18-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MELSHLALVC AAIAFSSIFV VSQAGITSTH ARVSEPSEEM SLETFPPPAG
60 70 80 90 100
YNAPEQVHIT QGDNAGRAMI ISWVMPLNED GSNVVTYWIA SSDGSDNKNA
110 120 130 140 150
IATTSSYRYF NYTSGYLHHA TIKKLEYDPS KSRSRCSLHI RYYSDLGQTY
160 170 180 190 200
ASNQTLYNYM SNPKGQAVLF VGDLSYADDH PNHDQRKWDS YGRFVEPSAA
210 220 230 240 250
YQPWSWAAGN YEIDYAQSIS ETQPFKPYKN RYHVPYKASQ STSPLWYSIK
260 270 280 290 300
RASTYIIVLS SYSAYDKYTP QNSWLQDELK KVNRSETSWL IVLVHAPWYN
310 320 330 340 350
SNNYHYMEGE SMRVTFEPWF VENKVDIVFA GHVHAYERSK RISNIHYNIT
360 370 380 390 400
DGMSTPVKDQ NAPIYITIGD GGNIEGIANS FTDPQPSYSA FREASFGHAL
410 420 430 440
LEIKNRTHAH YTWHRNKEDE AVIADSIWLK KRYYLPEEET A
Length:441
Mass (Da):50,362
Last modified:May 1, 2000 - v1
Checksum:i861E402A9A936424
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti319 – 3191W → M in AAP81218. 1 PublicationCurated
Sequence conflicti324 – 3241K → I in AAP81218. 1 PublicationCurated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF492663 mRNA. Translation: AAM15912.1.
AC007212 Genomic DNA. Translation: AAD31353.1.
CP002685 Genomic DNA. Translation: AEC06729.1.
BT026132 mRNA. Translation: ABG48488.1.
AY297745 mRNA. Translation: AAP81218.1.
PIRiF84560.
RefSeqiNP_179405.1. NM_127370.1.
UniGeneiAt.40038.

Genome annotation databases

EnsemblPlantsiAT2G18130.1; AT2G18130.1; AT2G18130.
GeneIDi816326.
KEGGiath:AT2G18130.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF492663 mRNA. Translation: AAM15912.1 .
AC007212 Genomic DNA. Translation: AAD31353.1 .
CP002685 Genomic DNA. Translation: AEC06729.1 .
BT026132 mRNA. Translation: ABG48488.1 .
AY297745 mRNA. Translation: AAP81218.1 .
PIRi F84560.
RefSeqi NP_179405.1. NM_127370.1.
UniGenei At.40038.

3D structure databases

ProteinModelPortali Q9SI18.
SMRi Q9SI18. Positions 43-439.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT2G18130.1 ; AT2G18130.1 ; AT2G18130 .
GeneIDi 816326.
KEGGi ath:AT2G18130.

Organism-specific databases

TAIRi AT2G18130.

Phylogenomic databases

eggNOGi COG1409.
HOGENOMi HOG000238330.
InParanoidi Q9SI18.
OMAi NTEGIAN.
PhylomeDBi Q9SI18.

Enzyme and pathway databases

BioCyci ARA:AT2G18130-MONOMER.

Gene expression databases

Genevestigatori Q9SI18.

Family and domain databases

Gene3Di 2.60.40.380. 1 hit.
3.60.21.10. 1 hit.
InterProi IPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR008963. Purple_acid_Pase-like_N.
IPR015914. Purple_acid_Pase_N.
IPR025733. Purple_acid_PPase_C_dom.
[Graphical view ]
Pfami PF00149. Metallophos. 1 hit.
PF14008. Metallophos_C. 1 hit.
[Graphical view ]
SUPFAMi SSF49363. SSF49363. 1 hit.
SSF56300. SSF56300. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Purple acid phosphatases of Arabidopsis thaliana. Comparative analysis and differential regulation by phosphate deprivation."
    Li D., Zhu H., Liu K., Liu X., Leggewie G., Udvardi M., Wang D.
    J. Biol. Chem. 277:27772-27781(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], INDUCTION, GENE FAMILY, NOMENCLATURE.
    Strain: cv. Col-1.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  3. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  4. "Arabidopsis ORF clones."
    Kim C.J., Chen H., Quinitio C., Shinn P., Ecker J.R.
    Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  5. "Identification of differentially displayed Arabidopsis thaliana acid phosphatase-encoding genes."
    Lohrasebi T., Malboobi M.A.
    Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 241-400.
    Tissue: Seedling.
  6. "Expression patterns of purple acid phosphatase genes in Arabidopsis organs and functional analysis of AtPAP23 predominantly transcribed in flower."
    Zhu H., Qian W., Lu X., Li D., Liu X., Liu K., Wang D.
    Plant Mol. Biol. 59:581-594(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TISSUE SPECIFICITY.

Entry informationi

Entry nameiPPA11_ARATH
AccessioniPrimary (citable) accession number: Q9SI18
Secondary accession number(s): Q7XY10
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: May 1, 2000
Last modified: November 26, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3