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Q9SI18 (PPA11_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 84. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Purple acid phosphatase 11

EC=3.1.3.2
Gene names
Name:PAP11
Synonyms:AT8
Ordered Locus Names:At2g18130
ORF Names:F8D23.9
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length441 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

A phosphate monoester + H2O = an alcohol + phosphate.

Cofactor

Binds 1 iron ion per subunit By similarity.

Binds 1 zinc ion per subunit By similarity.

Subunit structure

Homodimer By similarity.

Subcellular location

Secreted By similarity.

Tissue specificity

Specifically expressed in flowers. Ref.6

Induction

By phosphate deprivation. Ref.1

Sequence similarities

Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.

Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   LigandIron
Metal-binding
Zinc
   Molecular functionHydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processdephosphorylation

Inferred from sequence or structural similarity Ref.1Ref.6. Source: GOC

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionacid phosphatase activity

Inferred from sequence or structural similarity Ref.1Ref.6. Source: TAIR

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2424 Potential
Chain25 – 441417Purple acid phosphatase 11
PRO_0000372816

Regions

Region332 – 3343Substrate binding By similarity

Sites

Active site3051Proton donor By similarity
Metal binding1451Iron By similarity
Metal binding1731Iron By similarity
Metal binding1731Zinc By similarity
Metal binding1761Iron By similarity
Metal binding2101Zinc By similarity
Metal binding2951Zinc By similarity
Metal binding3321Zinc By similarity
Metal binding3341Iron By similarity
Binding site2101Substrate By similarity

Amino acid modifications

Glycosylation1111N-linked (GlcNAc...) Potential
Glycosylation1531N-linked (GlcNAc...) Potential
Glycosylation2831N-linked (GlcNAc...) Potential
Glycosylation3481N-linked (GlcNAc...) Potential
Glycosylation4051N-linked (GlcNAc...) Potential

Experimental info

Sequence conflict3191W → M in AAP81218. Ref.5
Sequence conflict3241K → I in AAP81218. Ref.5

Sequences

Sequence LengthMass (Da)Tools
Q9SI18 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 861E402A9A936424

FASTA44150,362
        10         20         30         40         50         60 
MELSHLALVC AAIAFSSIFV VSQAGITSTH ARVSEPSEEM SLETFPPPAG YNAPEQVHIT 

        70         80         90        100        110        120 
QGDNAGRAMI ISWVMPLNED GSNVVTYWIA SSDGSDNKNA IATTSSYRYF NYTSGYLHHA 

       130        140        150        160        170        180 
TIKKLEYDPS KSRSRCSLHI RYYSDLGQTY ASNQTLYNYM SNPKGQAVLF VGDLSYADDH 

       190        200        210        220        230        240 
PNHDQRKWDS YGRFVEPSAA YQPWSWAAGN YEIDYAQSIS ETQPFKPYKN RYHVPYKASQ 

       250        260        270        280        290        300 
STSPLWYSIK RASTYIIVLS SYSAYDKYTP QNSWLQDELK KVNRSETSWL IVLVHAPWYN 

       310        320        330        340        350        360 
SNNYHYMEGE SMRVTFEPWF VENKVDIVFA GHVHAYERSK RISNIHYNIT DGMSTPVKDQ 

       370        380        390        400        410        420 
NAPIYITIGD GGNIEGIANS FTDPQPSYSA FREASFGHAL LEIKNRTHAH YTWHRNKEDE 

       430        440 
AVIADSIWLK KRYYLPEEET A 

« Hide

References

« Hide 'large scale' references
[1]"Purple acid phosphatases of Arabidopsis thaliana. Comparative analysis and differential regulation by phosphate deprivation."
Li D., Zhu H., Liu K., Liu X., Leggewie G., Udvardi M., Wang D.
J. Biol. Chem. 277:27772-27781(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], INDUCTION, GENE FAMILY, NOMENCLATURE.
Strain: cv. Col-1.
[2]"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana."
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. expand/collapse author list , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.
Nature 402:761-768(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[4]"Arabidopsis ORF clones."
Kim C.J., Chen H., Quinitio C., Shinn P., Ecker J.R.
Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[5]"Identification of differentially displayed Arabidopsis thaliana acid phosphatase-encoding genes."
Lohrasebi T., Malboobi M.A.
Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 241-400.
Tissue: Seedling.
[6]"Expression patterns of purple acid phosphatase genes in Arabidopsis organs and functional analysis of AtPAP23 predominantly transcribed in flower."
Zhu H., Qian W., Lu X., Li D., Liu X., Liu K., Wang D.
Plant Mol. Biol. 59:581-594(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: TISSUE SPECIFICITY.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF492663 mRNA. Translation: AAM15912.1.
AC007212 Genomic DNA. Translation: AAD31353.1.
CP002685 Genomic DNA. Translation: AEC06729.1.
BT026132 mRNA. Translation: ABG48488.1.
AY297745 mRNA. Translation: AAP81218.1.
PIRF84560.
RefSeqNP_179405.1. NM_127370.1.
UniGeneAt.40038.

3D structure databases

ProteinModelPortalQ9SI18.
SMRQ9SI18. Positions 43-439.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT2G18130.1; AT2G18130.1; AT2G18130.
GeneID816326.
KEGGath:AT2G18130.

Organism-specific databases

TAIRAT2G18130.

Phylogenomic databases

eggNOGCOG1409.
HOGENOMHOG000238330.
InParanoidQ9SI18.
OMATHAFYEW.
PhylomeDBQ9SI18.
ProtClustDBCLSN2683029.

Enzyme and pathway databases

BioCycARA:AT2G18130-MONOMER.

Gene expression databases

GenevestigatorQ9SI18.

Family and domain databases

Gene3D2.60.40.380. 1 hit.
InterProIPR004843. Calcineurin-like_PHP_apaH.
IPR008963. Purple_acid_Pase-like_N.
IPR015914. Purple_acid_Pase_N.
IPR025733. Purple_acid_PPase_C_dom.
[Graphical view]
PfamPF00149. Metallophos. 1 hit.
PF14008. Metallophos_C. 1 hit.
[Graphical view]
SUPFAMSSF49363. SSF49363. 1 hit.
ProtoNetSearch...

Entry information

Entry namePPA11_ARATH
AccessionPrimary (citable) accession number: Q9SI18
Secondary accession number(s): Q7XY10
Entry history
Integrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: May 1, 2000
Last modified: April 16, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names