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Reviewed, UniProtKB/Swiss-Prot Q9SI17 (PER14_ARATH)

Last modified June 16, 2009. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Peroxidase 14
      Short name=Atperox P14
    EC=1.11.1.7
Gene names
Name: PER14
Synonyms: P14
Ordered Locus Names: At2g18140
ORF Names: F8D23.8
OrganismArabidopsis thaliana (Mouse-ear cress) [Complete proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis

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Protein attributes

Sequence length337 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Function

Removal of H2O2, oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.

Catalytic activity

Donor + H2O2 = oxidized donor + 2 H2O.

Cofactor

Binds 1 heme B (iron-protoporphyrin IX) group per subunit By similarity.

Binds 2 calcium ions per subunit By similarity.

Subcellular location

Secreted By similarity.

Miscellaneous

There are 73 peroxidase genes in A.thaliana.

Sequence similarities

Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.

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Ontologies

Keywords
   Biological processHydrogen peroxide
   Cellular componentSecreted
   DomainSignal
   LigandCalcium
Heme
Iron
Metal-binding
   Molecular functionOxidoreductase
Peroxidase
   PTMDisulfide bond
Glycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processhydrogen peroxide catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

oxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcell wall

Inferred from direct assay. Source: TAIR

extracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functioncalcium ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

electron carrier activity

Inferred from electronic annotation. Source: InterPro

heme binding

Inferred from electronic annotation. Source: InterPro

peroxidase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2222 Potential
Chain23 – 337315Peroxidase 14
PRO_0000023680

Sites

Active site751Proton acceptor By similarity
Metal binding761Calcium 1 By similarity
Metal binding791Calcium 1; via carbonyl oxygen By similarity
Metal binding811Calcium 1; via carbonyl oxygen By similarity
Metal binding831Calcium 1 By similarity
Metal binding851Calcium 1 By similarity
Metal binding2021Iron (heme axial ligand) By similarity
Metal binding2031Calcium 2 By similarity
Metal binding2541Calcium 2 By similarity
Metal binding2571Calcium 2 By similarity
Metal binding2621Calcium 2 By similarity
Binding site1721Substrate; via carbonyl oxygen By similarity
Site711Transition state stabilizer By similarity

Amino acid modifications

Glycosylation241N-linked (GlcNAc...) Potential
Glycosylation1911N-linked (GlcNAc...) Potential
Glycosylation2181N-linked (GlcNAc...) Potential
Glycosylation2491N-linked (GlcNAc...) Potential
Disulfide bond44 ↔ 124 By similarity
Disulfide bond77 ↔ 82 By similarity
Disulfide bond130 ↔ 331 By similarity
Disulfide bond209 ↔ 241 By similarity

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Sequences

Sequence LengthMass (Da)Tools
Q9SI17-1 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: CB07C9D9DC256A1A

FASTA33737,204
        10         20         30         40         50         60 
MARIGSFLIL LSLTYALTLC ICDNASNFGG NKRNLFPDFY RSSCPRAEEI VRSVVAKAFE 

        70         80         90        100        110        120 
RETRMAASLM RLHFHDCFVQ GCDGSLLLDT SGSIVTEKNS NPNSRSARGF EVVDEIKAAL 

       130        140        150        160        170        180 
ENECPNTVSC ADALTLAARD SSVLTGGPSW TVPLGRRDSA TASRAKPNKD LPEPDNLFDT 

       190        200        210        220        230        240 
IFLRFSNEGL NLTDLVALSG SHTIGFSRCT SFRQRLYNQS GSGSPDTTLE KSYAAILRQR 

       250        260        270        280        290        300 
CPRSGGDQNL SELDINSAGR FDNSYFKNLI ENMGLLNSDQ VLFSSNEQSR ELVKKYAEDQ 

       310        320        330 
EEFFEQFAES MIKMGKISPL TGSSGEIRKK CRKINNS

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References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana."
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. expand/collapse author list , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.
Nature 402:761-768(1999) [PubMed: 10617197] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]"Analysis and expression of the class III peroxidase large gene family in Arabidopsis thaliana."
Tognolli M., Penel C., Greppin H., Simon P.
Gene 288:129-138(2002) [PubMed: 12034502] [Abstract]
Cited for: GENE FAMILY ORGANIZATION, NOMENCLATURE.
Strain: cv. Columbia.

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Cross-references

Sequence databases

AC007212 Genomic DNA. Translation: AAD31352.1.
IPIIPI00540041.
PIRG84560.
RefSeqNP_179406.1.
UniGeneAt.52798

3D structure databases

HSSPHSSP built from PDB template 1QGJ based on UniProtKB Q39034.
ModBaseSearch...

Protein family/group databases

PeroxiBase95. AtPrx14.

Proteomic databases

PRIDEQ9SI17.

Genome annotation databases

GeneID816327.
GenomeReviewsGene locus AT2G18140 in contig CT485783_GR.
KEGGath:AT2G18140.
NMPDRfig|3702.1.peg.8808.

Organism-specific databases

GeneFarm1835. 61.
TAIRAt2g18140.

Enzyme and pathway databases

BRENDA1.11.1.7. 302.

Gene expression databases

ArrayExpressQ9SI17.
GermOnlineAT2G18140. Arabidopsis thaliana.

Family and domain databases

InterProIPR002016. Haem_peroxidase_pln/fun/bac.
IPR000823. Peroxidase_pln.
IPR019794. Peroxidases_AS.
IPR019793. Peroxidases_heam-ligand_BS.
[Graphical view]
PfamPF00141. peroxidase. 1 hit.
[Graphical view]
PRINTSPR00458. PEROXIDASE.
PR00461. PLPEROXIDASE.
PROSITEPS00435. PEROXIDASE_1. 1 hit.
PS00436. PEROXIDASE_2. 1 hit.
PS50873. PEROXIDASE_4. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry namePER14_ARATH
AccessionPrimary (citable) accession number: Q9SI17
Entry history
Integrated into UniProtKB/Swiss-Prot: November 25, 2002
Last sequence update: May 1, 2000
Last modified: June 16, 2009
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

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Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents