UniProtKB - Q9SHI7 (UBC34_ARATH)
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Protein
Ubiquitin-conjugating enzyme E2 34
Gene
UBC34
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.1 Publication
Catalytic activityi
S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.PROSITE-ProRule annotation
: protein ubiquitination Pathwayi
This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.PROSITE-ProRule annotationView all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 87 | Glycyl thioester intermediatePROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- ubiquitin protein ligase activity Source: GO_Central
- ubiquitin protein ligase binding Source: GO_Central
- ubiquitin-protein transferase activity Source: TAIR
GO - Biological processi
- protein polyubiquitination Source: GO_Central
- ubiquitin-dependent ERAD pathway Source: GO_Central
- ubiquitin-dependent protein catabolic process Source: TAIR
Keywordsi
Molecular function | Transferase |
Biological process | Ubl conjugation pathway |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
Reactomei | R-ATH-983168 Antigen processing: Ubiquitination & Proteasome degradation |
UniPathwayi | UPA00143 |
Names & Taxonomyi
Protein namesi | Recommended name: Ubiquitin-conjugating enzyme E2 34 (EC:2.3.2.23)Alternative name(s): E2 ubiquitin-conjugating enzyme 34 Ubiquitin carrier protein 34 |
Gene namesi | Name:UBC34 Ordered Locus Names:At1g17280 ORF Names:F20D23.1 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT1G17280 |
TAIRi | locus:2020392 AT1G17280 |
Subcellular locationi
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 214 – 234 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000345199 | 1 – 237 | Ubiquitin-conjugating enzyme E2 34Add BLAST | 237 |
Proteomic databases
PaxDbi | Q9SHI7 |
Expressioni
Gene expression databases
ExpressionAtlasi | Q9SHI7 baseline and differential |
Genevisiblei | Q9SHI7 AT |
Interactioni
GO - Molecular functioni
- ubiquitin protein ligase binding Source: GO_Central
Protein-protein interaction databases
BioGridi | 23540448 interactors. |
IntActi | Q9SHI7 1 interactor. |
STRINGi | 3702.AT1G17280.1 |
Structurei
3D structure databases
ProteinModelPortali | Q9SHI7 |
SMRi | Q9SHI7 |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Sequence similaritiesi
Belongs to the ubiquitin-conjugating enzyme family.PROSITE-ProRule annotation
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0894 Eukaryota ENOG410Z0AN LUCA |
HOGENOMi | HOG000170329 |
InParanoidi | Q9SHI7 |
KOi | K04554 |
OMAi | FQPPSIY |
OrthoDBi | EOG09360KZX |
PhylomeDBi | Q9SHI7 |
Family and domain databases
CDDi | cd00195 UBCc, 1 hit |
Gene3Di | 3.10.110.101 hit |
InterProi | View protein in InterPro IPR000608 UBQ-conjugat_E2 IPR016135 UBQ-conjugating_enzyme/RWD |
Pfami | View protein in Pfam PF00179 UQ_con, 1 hit |
SUPFAMi | SSF54495 SSF54495, 1 hit |
PROSITEi | View protein in PROSITE PS50127 UBIQUITIN_CONJUGAT_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9SHI7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAEKACIKRL QKEYRALCKE PVSHVVARPS PNDILEWHYV LEGSEGTPFA
60 70 80 90 100
GGFYYGKIKF PPEYPYKPPG ITMTTPNGRF MTQKKICLSM SDFHPESWNP
110 120 130 140 150
MWSVSSILTG LLSFMMDTSP TTGSVNTTVI EKQRLAKSSL AFNCKTPAFR
160 170 180 190 200
KLFPEYVEKY NQQQLAEQAT TQLTTPESPQ KSDTKVESEK TIDPTKGDSE
210 220 230
GGLKERKKNN KQGLPAWIIL LLVSVFGVVM ALPLLQL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC007651 Genomic DNA Translation: AAD50006.1 CP002684 Genomic DNA Translation: AEE29567.1 CP002684 Genomic DNA Translation: AEE29568.1 CP002684 Genomic DNA Translation: ANM59253.1 CP002684 Genomic DNA Translation: ANM59254.1 CP002684 Genomic DNA Translation: ANM59255.1 CP002684 Genomic DNA Translation: ANM59256.1 CP002684 Genomic DNA Translation: ANM59257.1 CP002684 Genomic DNA Translation: ANM59259.1 BT003073 mRNA Translation: AAO23638.1 AK227344 mRNA Translation: BAE99355.1 AY084676 mRNA Translation: AAM61238.1 DQ027047 mRNA Translation: AAY44873.1 |
PIRi | C86309 |
RefSeqi | NP_001077554.1, NM_001084085.1 NP_001319027.1, NM_001332287.1 NP_001321626.1, NM_001332292.1 NP_001321627.1, NM_001332293.1 NP_001321628.1, NM_001332288.1 NP_001321629.1, NM_001332290.1 NP_001321630.1, NM_001332291.1 NP_173172.1, NM_101590.4 |
UniGenei | At.42947 |
Genome annotation databases
EnsemblPlantsi | AT1G17280.1; AT1G17280.1; AT1G17280 AT1G17280.2; AT1G17280.2; AT1G17280 AT1G17280.3; AT1G17280.3; AT1G17280 AT1G17280.5; AT1G17280.5; AT1G17280 AT1G17280.6; AT1G17280.6; AT1G17280 AT1G17280.7; AT1G17280.7; AT1G17280 AT1G17280.8; AT1G17280.8; AT1G17280 AT1G17280.9; AT1G17280.9; AT1G17280 |
GeneIDi | 838300 |
Gramenei | AT1G17280.1; AT1G17280.1; AT1G17280 AT1G17280.2; AT1G17280.2; AT1G17280 AT1G17280.3; AT1G17280.3; AT1G17280 AT1G17280.5; AT1G17280.5; AT1G17280 AT1G17280.6; AT1G17280.6; AT1G17280 AT1G17280.7; AT1G17280.7; AT1G17280 AT1G17280.8; AT1G17280.8; AT1G17280 AT1G17280.9; AT1G17280.9; AT1G17280 |
KEGGi | ath:AT1G17280 |
Similar proteinsi
Entry informationi
Entry namei | UBC34_ARATH | |
Accessioni | Q9SHI7Primary (citable) accession number: Q9SHI7 Secondary accession number(s): Q4TYX7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 22, 2008 |
Last sequence update: | May 1, 2000 | |
Last modified: | April 25, 2018 | |
This is version 122 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |