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Protein

Glutathione S-transferase U24

Gene

GSTU24

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.By similarity

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

GO - Molecular functioni

  • glutathione binding Source: TAIR
  • glutathione transferase activity Source: TAIR

GO - Biological processi

  • 2,4,6-trinitrotoluene catabolic process Source: TAIR
  • glutathione metabolic process Source: GO_Central
  • toxin catabolic process Source: TAIR

Keywordsi

Molecular functionTransferase
Biological processDetoxification, Stress response

Enzyme and pathway databases

BioCyciARA:AT1G17170-MONOMER.
MetaCyc:AT1G17170-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase U24 (EC:2.5.1.18)
Short name:
AtGSTU24
Alternative name(s):
GST class-tau member 24
Gene namesi
Name:GSTU24
Ordered Locus Names:At1g17170
ORF Names:F20D23.13
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G17170.
TAIRilocus:2020322. AT1G17170.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004135691 – 218Glutathione S-transferase U24Add BLAST218

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei148PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ9SHH6.
PRIDEiQ9SHH6.

Expressioni

Inductioni

By acetochlor, metolachlor, 2,4,6-trinitrotoluene (TNT) and 2,6-dinitrotoluene (2,6-DNT).2 Publications

Gene expression databases

GenevisibleiQ9SHH6. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G17170.1.

Structurei

3D structure databases

ProteinModelPortaliQ9SHH6.
SMRiQ9SHH6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 82GST N-terminalAdd BLAST80
Domaini88 – 215GST C-terminalAdd BLAST128

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni13 – 14Glutathione bindingBy similarity2
Regioni39 – 40Glutathione bindingBy similarity2
Regioni53 – 54Glutathione bindingBy similarity2
Regioni66 – 67Glutathione bindingBy similarity2

Sequence similaritiesi

Belongs to the GST superfamily. Tau family.Curated

Phylogenomic databases

eggNOGiKOG0406. Eukaryota.
ENOG410XSIX. LUCA.
HOGENOMiHOG000125749.
InParanoidiQ9SHH6.
KOiK00799.
OMAiCSKLIAW.
OrthoDBiEOG09360PCQ.
PhylomeDBiQ9SHH6.

Family and domain databases

InterProiView protein in InterPro
IPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR012336. Thioredoxin-like_fold.
PfamiView protein in Pfam
PF02798. GST_N. 1 hit.
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiView protein in PROSITE
PS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9SHH6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADEVILLDF WASMFGMRTR IALAEKRVKY DHREEDLWNK SSLLLEMNPV
60 70 80 90 100
HKKIPVLIHN GKPVCESLIQ IEYIDETWPD NNPLLPSDPY KRAHAKFWAD
110 120 130 140 150
FIDKKVNVTA RRIWAVKGEE QEAAKELIEI LKTLESELGD KKYFGDETFG
160 170 180 190 200
YVDIALIGFH SWFAVYEKFG NVSIESECSK LVAWAKRCLE RESVAKALPE
210
SEKVITFISE RRKKLGLE
Length:218
Mass (Da):25,306
Last modified:May 1, 2000 - v1
Checksum:iAEC9508B1A776560
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007651 Genomic DNA. Translation: AAD50016.1.
CP002684 Genomic DNA. Translation: AEE29554.1.
BT012184 mRNA. Translation: AAS76278.1.
PIRiG86307.
RefSeqiNP_173160.1. NM_101578.3.
UniGeneiAt.41850.

Genome annotation databases

EnsemblPlantsiAT1G17170.1; AT1G17170.1; AT1G17170.
GeneIDi838288.
GrameneiAT1G17170.1; AT1G17170.1; AT1G17170.
KEGGiath:AT1G17170.

Similar proteinsi

Entry informationi

Entry nameiGSTUO_ARATH
AccessioniPrimary (citable) accession number: Q9SHH6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: May 1, 2000
Last modified: September 27, 2017
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families