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Protein

Glutathione S-transferase U24

Gene

GSTU24

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.By similarity

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

GO - Molecular functioni

  • glutathione binding Source: TAIR
  • glutathione transferase activity Source: TAIR

GO - Biological processi

  • 2,4,6-trinitrotoluene catabolic process Source: TAIR
  • glutathione metabolic process Source: GO_Central
  • toxin catabolic process Source: TAIR

Keywordsi

Molecular functionTransferase
Biological processDetoxification, Stress response

Enzyme and pathway databases

BioCyciARA:AT1G17170-MONOMER
MetaCyc:AT1G17170-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase U24 (EC:2.5.1.18)
Short name:
AtGSTU24
Alternative name(s):
GST class-tau member 24
Gene namesi
Name:GSTU24
Ordered Locus Names:At1g17170
ORF Names:F20D23.13
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G17170
TAIRilocus:2020322 AT1G17170

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004135691 – 218Glutathione S-transferase U24Add BLAST218

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei148PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ9SHH6
PRIDEiQ9SHH6

Expressioni

Inductioni

By acetochlor, metolachlor, 2,4,6-trinitrotoluene (TNT) and 2,6-dinitrotoluene (2,6-DNT).2 Publications

Gene expression databases

ExpressionAtlasiQ9SHH6 baseline and differential
GenevisibleiQ9SHH6 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G17170.1

Structurei

3D structure databases

ProteinModelPortaliQ9SHH6
SMRiQ9SHH6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 82GST N-terminalAdd BLAST80
Domaini88 – 215GST C-terminalAdd BLAST128

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni13 – 14Glutathione bindingBy similarity2
Regioni39 – 40Glutathione bindingBy similarity2
Regioni53 – 54Glutathione bindingBy similarity2
Regioni66 – 67Glutathione bindingBy similarity2

Sequence similaritiesi

Belongs to the GST superfamily. Tau family.Curated

Phylogenomic databases

eggNOGiKOG0406 Eukaryota
ENOG410XSIX LUCA
HOGENOMiHOG000125749
InParanoidiQ9SHH6
KOiK00799
OMAiCSKLIAW
OrthoDBiEOG09360PCQ
PhylomeDBiQ9SHH6

Family and domain databases

InterProiView protein in InterPro
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF02798 GST_N, 1 hit
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

Q9SHH6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADEVILLDF WASMFGMRTR IALAEKRVKY DHREEDLWNK SSLLLEMNPV
60 70 80 90 100
HKKIPVLIHN GKPVCESLIQ IEYIDETWPD NNPLLPSDPY KRAHAKFWAD
110 120 130 140 150
FIDKKVNVTA RRIWAVKGEE QEAAKELIEI LKTLESELGD KKYFGDETFG
160 170 180 190 200
YVDIALIGFH SWFAVYEKFG NVSIESECSK LVAWAKRCLE RESVAKALPE
210
SEKVITFISE RRKKLGLE
Length:218
Mass (Da):25,306
Last modified:May 1, 2000 - v1
Checksum:iAEC9508B1A776560
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007651 Genomic DNA Translation: AAD50016.1
CP002684 Genomic DNA Translation: AEE29554.1
BT012184 mRNA Translation: AAS76278.1
PIRiG86307
RefSeqiNP_173160.1, NM_101578.3
UniGeneiAt.41850

Genome annotation databases

EnsemblPlantsiAT1G17170.1; AT1G17170.1; AT1G17170
GeneIDi838288
GrameneiAT1G17170.1; AT1G17170.1; AT1G17170
KEGGiath:AT1G17170

Similar proteinsi

Entry informationi

Entry nameiGSTUO_ARATH
AccessioniPrimary (citable) accession number: Q9SHH6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: May 1, 2000
Last modified: April 25, 2018
This is version 123 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health