Q9SHG0 (TPS3_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 3
EC=2.4.1.15

Alternative name(s):
Trehalose-6-phosphate synthase 3
Short name=AtTPS3

Gene names

Name:	TPS3
Ordered Locus Names:	At1g17000
ORF Names:	F20D23.30

Organism

Arabidopsis thaliana (Mouse-ear cress) [Reference proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	783 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	UDP-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate.
Sequence similarities	In the N-terminal section; belongs to the glycosyltransferase 20 family. In the C-terminal section; belongs to the trehalose phosphatase family.
Sequence caution	The sequence AAD50035.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	trehalose biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular_function	alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 783	783	Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 3		PRO_0000324824
Regions
	Region	11 – 456	446	Glycosyltransferase
	Compositional bias	714 – 719	6	Poly-Ser
	Compositional bias	773 – 776	4	Poly-Thr

Sequences

	Sequence		Length	Mass (Da)
	Q9SHG0 [UniParc]. Last modified January 25, 2012. Version 3. Checksum: 262F05A09098887E	FASTA	783	89,483
	10 20 30 40 50 60 MGYDNVCGER QTLLVVANRL PASAKRTGEH SWSLEMSPGG KFNLLVEKDA VSKSLAEMKC 70 80 90 100 110 120 IPVFLNEVFD QYYNGYSNGI LWPILHHMGL PQEYDHDTIK TFETQYDAYK KANRMFLDVI 130 140 150 160 170 180 KENYKDGDIV WCQDYHLMFL PQYLKEYNNK IKVGWFLHSP FPSSEIYKTL PSRSELLRSV 190 200 210 220 230 240 LAADLISFHT YDFARHFVNT CTRILGVEGT HEGVVYQGRV TRVVVLPMGI YPNRFIKTCK 250 260 270 280 290 300 LPEVIQQMNE LKDRFSGKKV ILGVDRLDMI KGIPQKYLGF EKFLDENPNW RDKIVLVQIA 310 320 330 340 350 360 VPTRNEVPEY QKLKNQVHRL VGRINGRFGS VSSLPIHHMD CSVDSNYLCA LYAISDVMLV 370 380 390 400 410 420 TSLRDGLNLV SHEFVACQEA KRGVLILSEF AGAGQSLGAG ALLVNPWNVT EVSSAIKKAL 430 440 450 460 470 480 NMPYEERETR HRVNFKYVKT HSAEKWGFDF LSELNDAFDE SELQIRKIPH ELPQQDVIQR 490 500 510 520 530 540 YSLSNNRLII LGFYGTITEP RNSLSKEMDL KLNPELKETL KALCNDPKTT VVVLSRSGKN 550 560 570 580 590 600 ILDKNFGEYK IWLAAENGMF LKHTTEEWVT NMPQNMNLDW VDGLKNVFKY FTDRTPRSFF 610 620 630 640 650 660 EASKTSLVWN YEYADVEFGR AQARDLLQYL WAGPISNASA EVVRGKYSVE VHAIGVTKEP 670 680 690 700 710 720 EIGHILGEIV HKKAMTTPID YVFCSGYFLE KDEDIYTFFE SEILSPKLSH ETRSKSSSSN 730 740 750 760 770 780 HSLEKKVSLN VLDLKQENYF STAIGQARTK ARYVVDSSHN VVNLLHKLAV ANTTTTSVKK PNV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W. Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	"An unexpected plethora of trehalose biosynthesis genes in Arabidopsis thaliana." Leyman B., Van Dijck P., Thevelein J.M. Trends Plant Sci. 6:510-513(2001) [PubMed] [Europe PMC] [Abstract] Cited for: GENE FAMILY, NOMENCLATURE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC007651 Genomic DNA. Translation: AAD50035.1. Sequence problems. CP002684 Genomic DNA. Translation: AEE29529.1.
IPI	IPI00538265. IPI01019341.
PIR	F86305.
RefSeq	NP_173143.4. NM_101560.5.
UniGene	At.51643.
3D structure databases
ProteinModelPortal	Q9SHG0.
SMR	Q9SHG0. Positions 11-458.
ModBase	Search...
Protein-protein interaction databases
STRING	3702.AT1G17000.1-P.
Protein family/group databases
CAZy	GT20. Glycosyltransferase Family 20.
Proteomic databases
PaxDb	Q9SHG0.
PRIDE	Q9SHG0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	838270.
KEGG	ath:AT1G17000.
Organism-specific databases
TAIR	At1g17000.
Phylogenomic databases
eggNOG	COG0380.
InParanoid	Q9SHG0.
KO	K16055.
Gene expression databases
Genevestigator	Q9SHG0.
Family and domain databases
Gene3D	3.40.50.1000. 3 hits.
InterPro	IPR001830. Glyco_trans_20. IPR023214. HAD-like_dom. IPR003337. Trehalose_PPase. [Graphical view]
Pfam	PF00982. Glyco_transf_20. 1 hit. PF02358. Trehalose_PPase. 1 hit. [Graphical view]
SUPFAM	SSF56784. HAD-like_dom. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TPS3_ARATH

Accession

Primary (citable) accession number: Q9SHG0
Secondary accession number(s): F4I628

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 18, 2008
Last sequence update:	January 25, 2012
Last modified:	May 29, 2013
This is version 69 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program