Q9SGN7 (CCR12_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Serine/threonine-protein kinase-like protein At1g28390
EC=2.7.11.1

Alternative name(s):
CRINKLY 4-related kinase

Gene names

Ordered Locus Names:	At1g28390
ORF Names:	F3M18.17

Organism

Arabidopsis thaliana (Mouse-ear cress)

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	470 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	ATP + a protein = ADP + a phosphoprotein.
Sequence similarities	Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Contains 1 protein kinase domain.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Receptor Serine/threonine-protein kinase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine kinase activity Inferred from electronic annotation. Source: UniProtKB-KW receptor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Alternative products

This entry describes 1 isoform produced by alternative splicing. [Select]

Note: A number of isoforms are produced. According to EST sequences.

Isoform 1 (identifier: Q9SGN7-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 470	470	Serine/threonine-protein kinase-like protein At1g28390		PRO_0000382751
Regions
	Domain	52 – 333	282	Protein kinase
	Nucleotide binding	58 – 66	9	ATP By similarity
Sites
	Active site	186	1	Proton acceptor By similarity
	Binding site	81	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 91345428A7E4AE3B	FASTA	470	53,076
	10 20 30 40 50 60 MGYLSCNGES AVAICDTYNW NPRRRSKVPE KRHPPKLRVF NYDELAVATN GFSANNFLGK 70 80 90 100 110 120 GSHGRVYKAV LDDGKLLAAV KRTTITTTVG NNNNNVSQVD NEIEILSRVR HRWMVNLIGY 130 140 150 160 170 180 CVDHRRKTKL LVVEYMPNGT LHDQLHSRSS LDSRLSSWNR RIKHALQIAI AVHALHTAET 190 200 210 220 230 240 QVIHRDIKSC NVLIDGDGNA RLADFGLALI GNVDDERLKY TPPAGTLGYL DPSYLAPADL 250 260 270 280 290 300 TAKSDVFSFG ILLLEIISGR EAIDLNYSPS CIVDWAVPLI KRGDYDAICD LKIKNRPYYA 310 320 330 340 350 360 VIRKLAVMAA RCVRSTAKKR PDMLEVVECL KTVRQLSPAW NKLRRRSEER SENVLAVEEE 370 380 390 400 410 420 KEEIHVRIVR GGSRKNRKVS NVTTSVDDVY ERLVPEETLP FRRRNFVLRS RSVGAKVGPD 430 440 450 460 470 PYDGFGDETV VTMRLLIEKE RPVTTAAMRL SKSRSVGIVR SHKTASRKRY

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W. Nature 408:816-820(2000) [PubMed: 11130712] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	"Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R. Science 302:842-846(2003) [PubMed: 14593172] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[4]	"Diverse transcriptional programs associated with environmental stress and hormones in the Arabidopsis receptor-like kinase gene family." Chae L., Sudat S., Dudoit S., Zhu T., Luan S. Mol. Plant 2:84-107(2009) [PubMed: 19529822] [Abstract] Cited for: GENE FAMILY.

Web resources

PlantP kinase Classification PPC

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC010155 Genomic DNA. Translation: AAF16755.1. CP002684 Genomic DNA. Translation: AEE30966.1. AY075610 mRNA. Translation: AAL91624.1.
IPI	IPI00545930.
RefSeq	NP_174161.1. NM_102606.3.
UniGene	At.40900.
3D structure databases
ProteinModelPortal	Q9SGN7.
SMR	Q9SGN7. Positions 42-337.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9SGN7. 6 interactions.
Proteomic databases
PRIDE	Q9SGN7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT1G28390.1; AT1G28390.1; AT1G28390.
GeneID	839736.
GenomeReviews	Gene locus AT1G28390 in contig CT485782_GR.
KEGG	ath:AT1G28390.
NMPDR	fig|3702.1.peg.3183.
Organism-specific databases
GeneFarm	2037. 161.
TAIR	At1g28390.
Phylogenomic databases
eggNOG	KOG1187.
GeneTree	EPGT00070000028933.
HOGENOM	HBG755340.
InParanoid	Q9SGN7.
OMA	ESAVAIC.
PhylomeDB	Q9SGN7.
ProtClustDB	CLSN2679621.
Gene expression databases
Genevestigator	Q9SGN7.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR017442. Se/Thr_kinase-like_dom. IPR008271. Ser/Thr_kinase_AS. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CCR12_ARATH

Accession

Primary (citable) accession number: Q9SGN7

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 1, 2009
Last sequence update:	May 1, 2000
Last modified:	December 14, 2011
This is version 84 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program