Q9SGG3 (ALA5_ARATH) Reviewed, UniProtKB/Swiss-Prot
Last modified
December 14, 2011.
Version 92.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Putative phospholipid-transporting ATPase 5 Short name=AtALA5 EC=3.6.3.1 Alternative name(s): Aminophospholipid flippase 5 | ||||||
| Gene names |
| ||||||
| Organism | Arabidopsis thaliana (Mouse-ear cress) | ||||||
| Taxonomic identifier | 3702 [NCBI] | ||||||
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Protein attributes
| Sequence length | 1228 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Function | Involved in transport of phospholipids Potential. |
| Catalytic activity | ATP + H2O + phospholipid(In) = ADP + phosphate + phospholipid(Out). |
| Subcellular location | |
| Sequence similarities | Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. [View classification] |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Membrane |
| Domain | Transmembrane Transmembrane helix |
| Ligand | ATP-binding Magnesium Metal-binding Nucleotide-binding |
| Molecular function | Hydrolase |
| PTM | Phosphoprotein |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | cation transport Inferred from electronic annotation. Source: InterPro |
| Cellular component | integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanismInferred from electronic annotation. Source: InterPro magnesium ion bindingInferred from electronic annotation. Source: InterPro phospholipid-translocating ATPase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 1228 | 1228 | Putative phospholipid-transporting ATPase 5 | PRO_0000046389 | |||||
Regions | |||||||||
| Topological domain | 1 – 74 | 74 | Cytoplasmic Potential | ||||||
| Transmembrane | 75 – 96 | 22 | Helical; Potential | ||||||
| Topological domain | 97 – 100 | 4 | Extracellular Potential | ||||||
| Transmembrane | 101 – 123 | 23 | Helical; Potential | ||||||
| Topological domain | 124 – 305 | 182 | Cytoplasmic Potential | ||||||
| Transmembrane | 306 – 327 | 22 | Helical; Potential | ||||||
| Topological domain | 328 – 359 | 32 | Extracellular Potential | ||||||
| Transmembrane | 360 – 377 | 18 | Helical; Potential | ||||||
| Topological domain | 378 – 934 | 557 | Cytoplasmic Potential | ||||||
| Transmembrane | 935 – 954 | 20 | Helical; Potential | ||||||
| Topological domain | 955 – 968 | 14 | Extracellular Potential | ||||||
| Transmembrane | 969 – 988 | 20 | Helical; Potential | ||||||
| Topological domain | 989 – 1018 | 30 | Cytoplasmic Potential | ||||||
| Transmembrane | 1019 – 1041 | 23 | Helical; Potential | ||||||
| Topological domain | 1042 – 1054 | 13 | Extracellular Potential | ||||||
| Transmembrane | 1055 – 1077 | 23 | Helical; Potential | ||||||
| Topological domain | 1078 – 1083 | 6 | Cytoplasmic Potential | ||||||
| Transmembrane | 1084 – 1104 | 21 | Helical; Potential | ||||||
| Topological domain | 1105 – 1117 | 13 | Extracellular Potential | ||||||
| Transmembrane | 1118 – 1146 | 29 | Helical; Potential | ||||||
| Topological domain | 1147 – 1228 | 82 | Cytoplasmic Potential | ||||||
Sites | |||||||||
| Active site | 425 | 1 | 4-aspartylphosphate intermediate By similarity | ||||||
| Metal binding | 879 | 1 | Magnesium By similarity | ||||||
| Metal binding | 883 | 1 | Magnesium By similarity | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. Davis R.W.Nature 408:816-820(2000) [PubMed: 11130712] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia. |
| [2] | The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AC010926 Genomic DNA. Translation: AAG51844.1. CP002684 Genomic DNA. Translation: AEE35362.1. |
| IPI | IPI00528116. |
| PIR | G96751. |
| RefSeq | NP_177414.1. NM_105929.4. |
| UniGene | At.35067. |
3D structure databases | |
| ProteinModelPortal | Q9SGG3. |
| SMR | Q9SGG3. Positions 851-914. |
| ModBase | Search... |
Proteomic databases | |
| PRIDE | Q9SGG3. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblPlants | AT1G72700.1; AT1G72700.1; AT1G72700. |
| GeneID | 843602. |
| GenomeReviews | Gene locus AT1G72700 in contig CT485782_GR. |
| KEGG | ath:AT1G72700. |
| NMPDR | fig|3702.1.peg.6763. |
Organism-specific databases | |
| TAIR | At1g72700. |
Phylogenomic databases | |
| eggNOG | KOG0206. |
| GeneTree | EPGT00070000028188. |
| HOGENOM | HBG745019. |
| InParanoid | Q9SGG3. |
| OMA | NRSHGEK. |
| PhylomeDB | Q9SGG3. |
| ProtClustDB | CLSN2679593. |
Gene expression databases | |
| ArrayExpress | Q9SGG3. |
| Genevestigator | Q9SGG3. |
| GermOnline | AT1G72700. Arabidopsis thaliana. |
Family and domain databases | |
| InterPro | IPR023306. ATPase_cation_domN. IPR008250. ATPase_P-typ_ATPase-assoc-dom. IPR023300. ATPase_P-typ_cyto_domA. IPR023299. ATPase_P-typ_cyto_domN. IPR001757. ATPase_P-typ_ion-transptr. IPR018303. ATPase_P-typ_P_site. IPR006539. ATPase_P-typ_Plipid-transl. IPR023214. HAD-like_dom. [Graphical view] |
| Gene3D | G3DSA:2.70.150.10. ATPase_P-typ_cyto_domA. 2 hits. G3DSA:3.40.1110.10. ATPase_P-typ_cyto_domN. 2 hits. G3DSA:3.40.50.1000. HAD-like_dom. 2 hits. |
| KO | K01530. |
| Pfam | PF00122. E1-E2_ATPase. 1 hit. [Graphical view] |
| PRINTS | PR00119. CATATPASE. |
| SUPFAM | SSF81660. ATPase_cation_domN. 1 hit. SSF56784. HAD-like_dom. 1 hit. |
| TIGRFAMs | TIGR01652. ATPase-Plipid. 1 hit. TIGR01494. ATPase_P-type. 1 hit. |
| PROSITE | PS00154. ATPASE_E1_E2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | ALA5_ARATH | ||||||||
| Accession | Primary (citable) accession number: Q9SGG3 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Plant Protein Annotation Program | ||||||||
Relevant documents
| Arabidopsis thaliana Arabidopsis thaliana: entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with