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Protein

Mannan endo-1,4-beta-mannosidase 3

Gene

MAN3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei203Proton donorBy similarity1
Active sitei323NucleophileBy similarity1

GO - Molecular functioni

  • mannan endo-1,4-beta-mannosidase activity Source: TAIR

GO - Biological processi

  • detoxification of cadmium ion Source: TAIR
  • mannan catabolic process Source: GO_Central
  • response to cadmium ion Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Enzyme and pathway databases

BioCyciARA:AT3G10890-MONOMER.

Protein family/group databases

CAZyiGH5. Glycoside Hydrolase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Mannan endo-1,4-beta-mannosidase 3 (EC:3.2.1.78)
Alternative name(s):
Beta-mannanase 3
Endo-beta-1,4-mannanase 3
Short name:
AtMAN3
Gene namesi
Name:MAN3
Ordered Locus Names:At3g10890
ORF Names:T7M13.3
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

TAIRiAT3G10890.

Subcellular locationi

GO - Cellular componenti

  • apoplast Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_000027747620 – 414Mannan endo-1,4-beta-mannosidase 3Add BLAST395

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi17N-linked (GlcNAc...)Sequence analysis1
Glycosylationi75N-linked (GlcNAc...)Sequence analysis1
Glycosylationi133N-linked (GlcNAc...)Sequence analysis1
Glycosylationi153N-linked (GlcNAc...)Sequence analysis1
Glycosylationi343N-linked (GlcNAc...)Sequence analysis1
Glycosylationi386N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ9SG94.

Expressioni

Tissue specificityi

Expressed in leaves, flowers, siliques and seeds.1 Publication

Gene expression databases

GenevisibleiQ9SG94. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT3G10890.1.

Structurei

3D structure databases

ProteinModelPortaliQ9SG94.
SMRiQ9SG94.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IHRI. Eukaryota.
COG3934. LUCA.
HOGENOMiHOG000169952.
InParanoidiQ9SG94.
KOiK19355.
OMAiLECHLED.
OrthoDBiEOG09360BHK.
PhylomeDBiQ9SG94.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001547. Glyco_hydro_5.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF00150. Cellulase. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9SG94-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKCLCFVVLL AILIAQNSSD LGVKSASSDG FVSRKGVQFI LNGKPFYANG
60 70 80 90 100
FNAYWLAYEA TDSTTRFKIT YVFQNATIHD LTIVRTWGFR DGGYRALQIA
110 120 130 140 150
PGVYDEKTFQ GLDFAIAEAK RLGIKMIITF VNNYSDFGGR KQYVDWAKNT
160 170 180 190 200
GQNVSSDDDF YTNPLVKQYY KNHVKTMVNR VNTFTKVEYK DEPTIMGWEL
210 220 230 240 250
MNEPQCRADP SGKTLTAWMN EMALYVKSVD SKHLLSTGLE GFYGDSSPQR
260 270 280 290 300
KTSLNPVAAN VLGTDFIANH KLDAIDFASI HSYPDLWFPN LDEKSRLNLL
310 320 330 340 350
RKWLECHLED AQNILKKPLI LGEFGKPTNT PGYTQAQRDA VFNATFDTIY
360 370 380 390 400
ESAEKGGPAA GALFWHVISD GMNNFKDPLS IVLSENSTTV NIITEESRKL
410
GLIRGKGKLS KTKI
Length:414
Mass (Da):46,462
Last modified:May 1, 2000 - v1
Checksum:iBBACD11830EB2609
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011708 Genomic DNA. Translation: AAF19560.1.
CP002686 Genomic DNA. Translation: AEE74967.1.
RefSeqiNP_187700.1. NM_111926.2.
UniGeneiAt.39840.

Genome annotation databases

EnsemblPlantsiAT3G10890.1; AT3G10890.1; AT3G10890.
GeneIDi820259.
GrameneiAT3G10890.1; AT3G10890.1; AT3G10890.
KEGGiath:AT3G10890.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011708 Genomic DNA. Translation: AAF19560.1.
CP002686 Genomic DNA. Translation: AEE74967.1.
RefSeqiNP_187700.1. NM_111926.2.
UniGeneiAt.39840.

3D structure databases

ProteinModelPortaliQ9SG94.
SMRiQ9SG94.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT3G10890.1.

Protein family/group databases

CAZyiGH5. Glycoside Hydrolase Family 5.

Proteomic databases

PaxDbiQ9SG94.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G10890.1; AT3G10890.1; AT3G10890.
GeneIDi820259.
GrameneiAT3G10890.1; AT3G10890.1; AT3G10890.
KEGGiath:AT3G10890.

Organism-specific databases

TAIRiAT3G10890.

Phylogenomic databases

eggNOGiENOG410IHRI. Eukaryota.
COG3934. LUCA.
HOGENOMiHOG000169952.
InParanoidiQ9SG94.
KOiK19355.
OMAiLECHLED.
OrthoDBiEOG09360BHK.
PhylomeDBiQ9SG94.

Enzyme and pathway databases

BioCyciARA:AT3G10890-MONOMER.

Miscellaneous databases

PROiQ9SG94.

Gene expression databases

GenevisibleiQ9SG94. AT.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001547. Glyco_hydro_5.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF00150. Cellulase. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiMAN3_ARATH
AccessioniPrimary (citable) accession number: Q9SG94
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: May 1, 2000
Last modified: November 30, 2016
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.