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Q9SFB8 (PI5K6_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 92. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphatidylinositol 4-phosphate 5-kinase 6

Short name=AtPIP5K6
EC=2.7.1.68
Alternative name(s):
1-phosphatidylinositol 4-phosphate kinase 6
Diphosphoinositide kinase 6
PtdIns(4)P-5-kinase 6
Gene names
Name:PIP5K6
Ordered Locus Names:At3g07960
ORF Names:F17A17.30
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length715 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.

Sequence similarities

Contains 8 MORN repeats.

Contains 1 PIPK domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 715715Phosphatidylinositol 4-phosphate 5-kinase 6
PRO_0000185478

Regions

Repeat32 – 5423MORN 1
Repeat55 – 7723MORN 2
Repeat78 – 10023MORN 3
Repeat101 – 12323MORN 4
Repeat124 – 14623MORN 5
Repeat147 – 16923MORN 6
Repeat170 – 19223MORN 7
Repeat193 – 21422MORN 8
Domain321 – 711391PIPK
Region671 – 69222Activation loop By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9SFB8 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 795D86CEB1FB52E9

FASTA71581,422
        10         20         30         40         50         60 
MSVAHADDAD DYSRPTGESY HAEKALPSGD FYTGQWRDNL PHGHGKYLWT DGCMYVGDWH 

        70         80         90        100        110        120 
RGKTMGKGRF SWPSGATYEG DFKNGYMDGK GTYIDSSGDL YRGSWVMNLR HGQGTKSYVN 

       130        140        150        160        170        180 
GDCYDGEWRR GLQDGHGRYQ WKNENHYIGQ WKNGLMNGNG TMIWSNGNRY DGSWEDGAPK 

       190        200        210        220        230        240 
GNGTFRWSDG SFYVGVWSKD PKEQNGTYYP STSSGNFDWQ PQQVFYVDLS ECVVCTCQRI 

       250        260        270        280        290        300 
PVLPSQKMPV WYGASEQSSS GNRTKNSERP RRRSVDGRVS NGEMELRSNG SGYLQVDDNA 

       310        320        330        340        350        360 
ESTRSSLGPL RIQPAKKQGQ TISKGHKNYE LMLNLQLGIR HSVGRPAPAT SLDLKASAFD 

       370        380        390        400        410        420 
PKEKLWTKFP SEGSKYTPPH QSCEFKWKDY CPVVFRTLRK LFSVDAADYM LSICGNDALR 

       430        440        450        460        470        480 
ELSSPGKSGS FFYLTNDDRY MIKTMKKAET KVLIRMLPAY YNHVRACENT LVTKFFGLHC 

       490        500        510        520        530        540 
VKLTGTAQKK VRFVIMGNLF CTGHSIHRRF DLKGSSHGRL TTKPESEIDP NTTLKDLDLN 

       550        560        570        580        590        600 
FAFRLQKNWF QEFCRQVDRD CEFLEQERIM DYSLLVGLHF REAAIKDSAT PTSGARTPTG 

       610        620        630        640        650        660 
NSETRLSRAE MDRFLLDASK LASIKLGINM PARVERTARR SDCENQLVGD PTGEFYDVIV 

       670        680        690        700        710 
YFGIIDILQD YDISKKLEHA YKSMQYDPTS ISAVDPKQYS RRFRDFIFRV FVEDA 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana."
Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F. expand/collapse author list , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
Nature 408:820-822(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Inositol phospholipid metabolism in Arabidopsis. Characterized and putative isoforms of inositol phospholipid kinase and phosphoinositide-specific phospholipase C."
Mueller-Roeber B., Pical C.
Plant Physiol. 130:22-46(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC013483 Genomic DNA. Translation: AAF21206.1.
CP002686 Genomic DNA. Translation: AEE74625.1.
BT008595 mRNA. Translation: AAP40421.1.
RefSeqNP_187453.1. NM_111675.5.
UniGeneAt.40277.

3D structure databases

ProteinModelPortalQ9SFB8.
SMRQ9SFB8. Positions 21-202, 331-707.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid5322. 1 interaction.

Proteomic databases

PaxDbQ9SFB8.
PRIDEQ9SFB8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT3G07960.1; AT3G07960.1; AT3G07960.
GeneID819987.
KEGGath:AT3G07960.

Organism-specific databases

TAIRAT3G07960.

Phylogenomic databases

eggNOGCOG4642.
HOGENOMHOG000193875.
InParanoidQ9SFB8.
KOK00889.
OMAMNGNGTM.
PhylomeDBQ9SFB8.
ProtClustDBCLSN2683759.

Enzyme and pathway databases

BioCycARA:AT3G07960-MONOMER.

Gene expression databases

GenevestigatorQ9SFB8.

Family and domain databases

Gene3D3.30.800.10. 1 hit.
3.30.810.10. 2 hits.
InterProIPR003409. MORN.
IPR017163. PIno-4-P-5_kinase_pln.
IPR023610. PInositol-4-P-5-kinase.
IPR027483. PInositol-4-P-5-kinase_C.
IPR002498. PInositol-4-P-5-kinase_core.
IPR027484. PInositol-4-P-5-kinase_N.
IPR016034. PInositol-4P-5-kinase_core_sub.
[Graphical view]
PANTHERPTHR23086. PTHR23086. 1 hit.
PfamPF02493. MORN. 7 hits.
PF01504. PIP5K. 1 hit.
[Graphical view]
PIRSFPIRSF037274. PIP5K_plant_prd. 1 hit.
SMARTSM00698. MORN. 7 hits.
SM00330. PIPKc. 1 hit.
[Graphical view]
PROSITEPS51455. PIPK. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePI5K6_ARATH
AccessionPrimary (citable) accession number: Q9SFB8
Entry history
Integrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: May 1, 2000
Last modified: April 16, 2014
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names