Q9SEA0 (CCS_CITSI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Capsanthin/capsorubin synthase, chromoplast
EC=5.3.99.8

Gene names

Name:

CCS

Organism

Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis)

Taxonomic identifier

2711 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Sapindales › Rutaceae › Citrus

Protein attributes

Sequence length	503 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of the ubiquitous 5,6-epoxycarotenoids, antheraxanthin and violaxanthin, into capsanthin and capsorubin, respectively.
Catalytic activity	Violaxanthin = capsorubin. Antheraxanthin = capsanthin.
Pathway	Carotenoid biosynthesis; capsanthin biosynthesis; capsanthin from antheraxanthin: step 1/1. Carotenoid biosynthesis; capsorubin biosynthesis; capsorubin from violaxanthin: step 1/1.
Subcellular location	Plastid › chromoplast By similarity.
Sequence similarities	Belongs to the lycopene cyclase family.

Ontologies

Keywords
Biological process	Carotenoid biosynthesis
Cellular component	Chromoplast Plastid
Domain	Transit peptide
Ligand	NAD
Molecular function	Isomerase Oxidoreductase
Gene Ontology (GO)
Biological_process	carotenoid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	chromoplast Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	capsanthin synthase activity Inferred from electronic annotation. Source: EC capsorubin synthase activity Inferred from electronic annotation. Source: EC oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – ?		Chromoplast Potential
	Chain	? – 503		Capsanthin/capsorubin synthase, chromoplast		PRO_0000018437
Regions
	Nucleotide binding	88 – 117	30	NAD Potential

Sequences

	Sequence		Length	Mass (Da)
	Q9SEA0 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 2C957F0AA91075E6	FASTA	503	56,663
	10 20 30 40 50 60 MATLLSPFSP SPLAKVSQII DSTSSPSFSL FPLGRQNACS RKADHHHHHR IRTSKFGNFL 70 80 90 100 110 120 ELTPESVPEF LDFDLPWFHP SDRIRYDVII IGTGPAGLRL AEQVSSRHSV KVCCVDPSPL 130 140 150 160 170 180 STWPNNYGVW VDEFEDIGLV DCLDKTWPMT CVFINDHKTK YLDRPYGRVS RNILKTKLLE 190 200 210 220 230 240 NCVSNGVKFH KAKVWHVNHQ EFESSIVCDD GNEIKASLIV DASGFASSFV EYDKPRNHGY 250 260 270 280 290 300 QIAHGILAEV ESHPFDLDKM VLMDWRDSHL GNEPYLRASN LKLPTFLYAM PFDSNLVFLE 310 320 330 340 350 360 ETSLVSRPVL SYKEVKSRMA ARLRHMGIRV KRVIEDEKCL IPMGGPLPVI PQSVMAIGGT 370 380 390 400 410 420 SGLIHPATGY MVARTMALAP ALADAIAECL GSTRMIRGRP LHQKVWNGLW PIDRRCNREF 430 440 450 460 470 480 YSFGMETLLK LDLKGTRRFF DAFFDLNPYY WHGFLSSRLS LAELAGLSLS LFGHASNSSR 490 500 LDIVTKCPVP LVKMMGNLAL ETI

References

[1]	"Molecular cloning of full length capsanthin/capsorubin synthase homologous gene from orange (Citrus sinensis)." Xu C.J., Chen D.M., Zhang S.L. Shi Yan Sheng Wu Xue Bao 34:147-150(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF169241 Genomic DNA. Translation: AAF18389.1.
3D structure databases
ProteinModelPortal	Q9SEA0.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Enzyme and pathway databases
UniPathway	UPA00806; UER00774. UPA00807; UER00775.
Family and domain databases
InterPro	IPR010108. Lycopene_cyclase_b/e. IPR008671. Lycopene_cyclase_FAD-bd. [Graphical view]
Pfam	PF05834. Lycopene_cycl. 1 hit. [Graphical view]
TIGRFAMs	TIGR01790. carotene-cycl. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CCS_CITSI

Accession

Primary (citable) accession number: Q9SEA0

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	May 1, 2000
Last modified:	October 3, 2012
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program