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Q9SE26

- ACEA_DENCR

UniProt

Q9SE26 - ACEA_DENCR

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Protein
Isocitrate lyase
Gene
ICL
Organism
Dendrobium crumenatum (Tropical pigeon orchid)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Isocitrate = succinate + glyoxylate.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei212 – 2121 Inferred

GO - Molecular functioni

  1. isocitrate lyase activity Source: UniProtKB-EC

GO - Biological processi

  1. glyoxylate cycle Source: UniProtKB-UniPathway
  2. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Glyoxylate bypass, Tricarboxylic acid cycle

Enzyme and pathway databases

UniPathwayiUPA00703; UER00719.

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate lyase (EC:4.1.3.1)
Short name:
ICL
Short name:
Isocitrase
Short name:
Isocitratase
Gene namesi
Name:ICL
OrganismiDendrobium crumenatum (Tropical pigeon orchid)
Taxonomic identifieri51096 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaAsparagalesOrchidaceaeEpidendroideaeDendrobiinaeDendrobium

Subcellular locationi

GO - Cellular componenti

  1. glyoxysome Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Glyoxysome, Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 574574Isocitrate lyase
PRO_0000068805Add
BLAST

Expressioni

Developmental stagei

Expressed maximally during postgerminative growth.

Interactioni

Subunit structurei

Homotetramer By similarity.

Structurei

3D structure databases

ProteinModelPortaliQ9SE26.
SMRiQ9SE26. Positions 8-534.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi572 – 5743Microbody targeting signal Reviewed prediction

Sequence similaritiesi

Family and domain databases

Gene3Di3.20.20.60. 2 hits.
InterProiIPR006254. Isocitrate_lyase.
IPR018523. Isocitrate_lyase_ph_CS.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PANTHERiPTHR21631:SF3. PTHR21631:SF3. 1 hit.
PfamiPF00463. ICL. 1 hit.
[Graphical view]
PIRSFiPIRSF001362. Isocit_lyase. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR01346. isocit_lyase. 1 hit.
PROSITEiPS00161. ISOCITRATE_LYASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9SE26-1 [UniParc]FASTAAdd to Basket

« Hide

MASSSVPPMI TEEEARFEAE VSAVESWWRT DRFRLTRRPY SARDVVSLRG    50
TLHHSYASDQ MAKKLWRTLK SHQSAGTASR TFGALDPVQV TMMAKHLDTI 100
YVSGWQCSST HTATNEPGPD LADYPYNTVP NKVEHLFFAQ LYHDRKQHEA 150
RVSMTREQRA KTPYVDYLRP IIADGDTGFG GATATVKLCK LFVERGAAGV 200
HIEDQSSVTK KCGHMAGKVL VAVSEHINRL VAARLQFDVM GVETVLVART 250
DAVAATLIQS NVDLRDHQFI LGATNPDFKR RSLAAVLSAA MAAGKTGAVL 300
QAIEDDWLSR AGLMTFSDAV INGINRQNLP EYEKQRRLNE WAAATEYSKC 350
VSNEQGREIA ERLGAGEIFW DWDIARTREG FYRFRGSVEA AVVRGRAFAP 400
HADLIWMETS SPDLVECGKF AQGMKASHPE IMLAYNLSPS FNWDAAGMTD 450
EEMRDFIPRI AKMGFCWQFI TLGGFHADAL VTDTFAREFA KQGMLAYVER 500
IQREERNNGV DTLAHQKWSG ANYYDRYLKT VQGGISSTAA MGKGVTEEQF 550
KEESRTGTRG LDRGGITVNA KSRL 574
Length:574
Mass (Da):63,993
Last modified:May 1, 2000 - v1
Checksum:i0B568ADE3248DE2E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF193815 mRNA. Translation: AAF04598.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF193815 mRNA. Translation: AAF04598.1 .

3D structure databases

ProteinModelPortali Q9SE26.
SMRi Q9SE26. Positions 8-534.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00703 ; UER00719 .

Family and domain databases

Gene3Di 3.20.20.60. 2 hits.
InterProi IPR006254. Isocitrate_lyase.
IPR018523. Isocitrate_lyase_ph_CS.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
PANTHERi PTHR21631:SF3. PTHR21631:SF3. 1 hit.
Pfami PF00463. ICL. 1 hit.
[Graphical view ]
PIRSFi PIRSF001362. Isocit_lyase. 1 hit.
SUPFAMi SSF51621. SSF51621. 1 hit.
TIGRFAMsi TIGR01346. isocit_lyase. 1 hit.
PROSITEi PS00161. ISOCITRATE_LYASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Sequence analysis of DcrIcl, an isocitrate lyase gene from the tropical orchid, Dendrobium crumenatum."
    Vellupillai M., Goh C.-J., Swarup S.
    Plant Gene Register PGR99-178
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiACEA_DENCR
AccessioniPrimary (citable) accession number: Q9SE26
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 2000
Last modified: May 14, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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