Q9SE20 (ZDS_SOLLC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Zeta-carotene desaturase, chloroplastic/chromoplastic
EC=1.3.5.6

Alternative name(s):
9,9'-di-cis-zeta-carotene desaturase
Carotene 7,8-desaturase

Gene names

Name:

ZDS

Organism

Solanum lycopersicum (Tomato) (Lycopersicon esculentum) [Reference proteome]

Taxonomic identifier

4081 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Solanales › Solanaceae › Solanoideae › Solaneae › Solanum › Lycopersicon

Protein attributes

Sequence length	588 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'.
Catalytic activity	9,9'-di-cis-zeta-carotene + 2 quinone = 7,9,7',9'-tetra-cis-lycopene + 2 quinol.
Cofactor	NAD, NADP, or FAD Probable.
Pathway	Carotenoid biosynthesis; lycopene biosynthesis.
Subcellular location	Plastid › chloroplast. Plastid › chromoplast.
Sequence similarities	Belongs to the zeta carotene desaturase family.

Ontologies

Keywords
Biological process	Carotenoid biosynthesis
Cellular component	Chloroplast Chromoplast Plastid
Domain	Transit peptide
Ligand	FAD Flavoprotein NAD
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	9,9'-di-cis-zeta-carotene desaturation to 7,9,7',9'-tetra-cis-lycopene Inferred from electronic annotation. Source: EC carotenoid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	chloroplast Inferred from electronic annotation. Source: UniProtKB-SubCell chromoplast Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	7,9,9'-tricis-neurosporene:quinone oxidoreductase activity Inferred from electronic annotation. Source: EC 9,9'-dicis-carotene:quinone oxidoreductase activity Inferred from electronic annotation. Source: EC carotene 7,8-desaturase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – ?		Chloroplast and chromoplast Potential
	Chain	? – 588		Zeta-carotene desaturase, chloroplastic/chromoplastic		PRO_0000041607

Sequences

	Sequence		Length	Mass (Da)
	Q9SE20 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 786675800C11B846	FASTA	588	64,733
	10 20 30 40 50 60 MATSSAYLSC PATSATGKKH VFPNGSPGFL VFGGTRLSNR LVTRKSVIRA DLDSMVSDMS 70 80 90 100 110 120 TNAPKGLFPP EPEHYRGPKL KVAIIGAGLA GMSTAVELLD QGHEVDIYES RTFIGGKVGS 130 140 150 160 170 180 FVDRRGNHIE MGLHVFFGCY NNLFRLLKKV GAEKNLLVKE HTHTFVNKGG EIGELDFRFP 190 200 210 220 230 240 VGAPLHGINA FLSTNQLKIY DKARNAVALA LSPVVRALVD PDGALQQIRD LDNVSFSEWF 250 260 270 280 290 300 LSKGGTRASI QRMWDPVAYA LGFIDCDNMS ARCMLTIFAL FATKTEASLL RMLKGSPDVY 310 320 330 340 350 360 LSGPIKKYIM DKGGRFHLRW GCREVLYETS SDGSMYVSGL AMSKATQKKI VKADAYVAAC 370 380 390 400 410 420 DVPGIKRLVP QKWRELEFFD NIYKLVGVPV VTVQLRYNGW VTELQDLERS RQLKRAAGLD 430 440 450 460 470 480 NLLYTPDADF SCFADLALAS PDDYYIEGQG SLLQCVLTPG DPYMPLSNDE IIKRVTKQVL 490 500 510 520 530 540 ALFPSSQGLE VTWSSVLKIG QSLYREGPGK DPFRPDQKTP VENFFLAGSY TKQDYIDSME 550 560 570 580 GATLSGRQAS AYICNVGEQL MALRKKITAA ELNDISKGVS LSDELSLV

References

[1]	"Zeta-carotene desaturase from tomato." Bartley G.E., Ishida B.K. Plant Gene Register PGR99-181 Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF195507 mRNA. Translation: AAF13698.1.
RefSeq	NP_001234383.1. NM_001247454.1.
UniGene	Les.13758.
3D structure databases
ProteinModelPortal	Q9SE20.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	543629.
Enzyme and pathway databases
UniPathway	UPA00803.
Family and domain databases
InterPro	IPR002937. Amino_oxidase. IPR014103. Zeta_caro_desat. [Graphical view]
Pfam	PF01593. Amino_oxidase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02732. zeta_caro_desat. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ZDS_SOLLC

Accession

Primary (citable) accession number: Q9SE20

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 2, 2001
Last sequence update:	May 1, 2000
Last modified:	March 6, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program