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Protein

Phosphoglucomutase, chloroplastic

Gene

PGMP

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

This enzyme participates in both the breakdown and synthesis of glucose.By similarity

Catalytic activityi

Alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.

Cofactori

Mg2+By similarityNote: Binds 1 Mg2+ ion per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei84SubstrateBy similarity1
Binding sitei88SubstrateBy similarity1
Active sitei181Phosphoserine intermediateBy similarity1
Metal bindingi181Magnesium; via phosphate groupBy similarity1
Binding sitei194SubstrateBy similarity1
Metal bindingi346MagnesiumBy similarity1
Metal bindingi348MagnesiumBy similarity1
Metal bindingi350MagnesiumBy similarity1
Binding sitei414SubstrateBy similarity1
Binding sitei446SubstrateBy similarity1
Binding sitei576SubstrateBy similarity1

GO - Molecular functioni

  • magnesium ion binding Source: InterPro
  • phosphoglucomutase activity Source: TAIR

GO - Biological processi

  • carbohydrate metabolic process Source: TAIR
  • detection of gravity Source: TAIR
  • galactose catabolic process Source: GO_Central
  • glucose metabolic process Source: GO_Central
  • glycogen biosynthetic process Source: GO_Central
  • response to cold Source: TAIR
  • starch biosynthetic process Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Carbohydrate metabolism, Glucose metabolism

Keywords - Ligandi

Magnesium, Metal-binding

Enzyme and pathway databases

BioCyciMetaCyc:AT5G51820-MONOMER.
BRENDAi5.4.2.2. 399.
ReactomeiR-ATH-3322077. Glycogen synthesis.
R-ATH-6798695. Neutrophil degranulation.
R-ATH-70221. Glycogen breakdown (glycogenolysis).
R-ATH-70370. Galactose catabolism.
SABIO-RKQ9SCY0.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglucomutase, chloroplastic (EC:5.4.2.2)
Short name:
PGM
Alternative name(s):
Glucose phosphomutase
Gene namesi
Name:PGMP
Synonyms:PGM
Ordered Locus Names:At5g51820
ORF Names:MIO24.4
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

TAIRiAT5G51820.

Subcellular locationi

GO - Cellular componenti

  • apoplast Source: TAIR
  • chloroplast Source: TAIR
  • chloroplast envelope Source: TAIR
  • chloroplast stroma Source: TAIR
  • cytosol Source: GO_Central
  • stromule Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Chloroplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 63ChloroplastSequence analysisAdd BLAST63
ChainiPRO_000002389564 – 623Phosphoglucomutase, chloroplasticAdd BLAST560

Proteomic databases

PaxDbiQ9SCY0.
PRIDEiQ9SCY0.

PTM databases

iPTMnetiQ9SCY0.

Expressioni

Gene expression databases

GenevisibleiQ9SCY0. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT5G51820.1.

Structurei

3D structure databases

ProteinModelPortaliQ9SCY0.
SMRiQ9SCY0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni181 – 182Substrate bindingBy similarity2
Regioni350 – 351Substrate bindingBy similarity2
Regioni433 – 435Substrate bindingBy similarity3

Sequence similaritiesi

Belongs to the phosphohexose mutase family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG0625. Eukaryota.
COG0033. LUCA.
HOGENOMiHOG000009550.
InParanoidiQ9SCY0.
KOiK01835.
OMAiNAQEAIP.
OrthoDBiEOG0936067I.
PhylomeDBiQ9SCY0.

Family and domain databases

Gene3Di3.30.310.50. 1 hit.
3.40.120.10. 3 hits.
InterProiIPR005844. A-D-PHexomutase_a/b/a-I.
IPR016055. A-D-PHexomutase_a/b/a-I/II/III.
IPR005845. A-D-PHexomutase_a/b/a-II.
IPR005846. A-D-PHexomutase_a/b/a-III.
IPR005843. A-D-PHexomutase_C.
IPR016066. A-D-PHexomutase_CS.
IPR005841. Alpha-D-phosphohexomutase_SF.
[Graphical view]
PfamiPF02878. PGM_PMM_I. 1 hit.
PF02879. PGM_PMM_II. 1 hit.
PF02880. PGM_PMM_III. 1 hit.
PF00408. PGM_PMM_IV. 1 hit.
[Graphical view]
PRINTSiPR00509. PGMPMM.
SUPFAMiSSF53738. SSF53738. 3 hits.
SSF55957. SSF55957. 1 hit.
PROSITEiPS00710. PGM_PMM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9SCY0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSTYTRFDT VFLFSRFAGA KYSPLLPSPS FTLSTSGIHI RTKPNSRFHS
60 70 80 90 100
IIASSSSSSV VAGTDSIEIK SLPTKPIEGQ KTGTSGLRKK VKVFMEDNYL
110 120 130 140 150
ANWIQALFNS LPLEDYKNAT LVLGGDGRYF NKEASQIIIK IAAGNGVGQI
160 170 180 190 200
LVGKEGILST PAVSAVIRKR KANGGFIMSA SHNPGGPEYD WGIKFNYSSG
210 220 230 240 250
QPAPETITDK IYGNTLSISE IKVAEIPDID LSQVGVTKYG NFSVEVIDPV
260 270 280 290 300
SDYLELMEDV FDFDLIRGLL SRSDFGFMFD AMHAVTGAYA KPIFVDNLGA
310 320 330 340 350
KPDSISNGVP LEDFGHGHPD PNLTYAKDLV DVMYRDNGPD FGAASDGDGD
360 370 380 390 400
RNMVLGNKFF VTPSDSVAII AANAQEAIPY FRAGPKGLAR SMPTSGALDR
410 420 430 440 450
VAEKLKLPFF EVPTGWKFFG NLMDAGKLSI CGEESFGTGS DHIREKDGIW
460 470 480 490 500
AVLAWLSILA HRNKDTKPGD KLVSVADVVK EYWATYGRNF FSRYDYEECE
510 520 530 540 550
SEGANKMIEY LREILSKSKA GDVYGNYVLQ FADDFSYTDP VDGSVASKQG
560 570 580 590 600
VRFVFTDGSR IIFRLSGTGS AGATVRIYIE QFEPDVSKHD VDAQIALKPL
610 620
IDLALSVSKL KDFTGREKPT VIT
Length:623
Mass (Da):67,989
Last modified:January 24, 2001 - v2
Checksum:i3D4A0D8132EF90F1
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti439G → V in CAB64725 (PubMed:10759515).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ242601 mRNA. Translation: CAB64725.1.
AF216580 mRNA. Translation: AAG44095.1.
AB010074 Genomic DNA. Translation: BAB11251.1.
CP002688 Genomic DNA. Translation: AED96131.1.
AY099708 mRNA. Translation: AAM20559.1.
AY128901 mRNA. Translation: AAM91301.1.
PIRiT52656.
RefSeqiNP_199995.1. NM_124561.3.
UniGeneiAt.1528.

Genome annotation databases

EnsemblPlantsiAT5G51820.1; AT5G51820.1; AT5G51820.
GeneIDi835257.
GrameneiAT5G51820.1; AT5G51820.1; AT5G51820.
KEGGiath:AT5G51820.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ242601 mRNA. Translation: CAB64725.1.
AF216580 mRNA. Translation: AAG44095.1.
AB010074 Genomic DNA. Translation: BAB11251.1.
CP002688 Genomic DNA. Translation: AED96131.1.
AY099708 mRNA. Translation: AAM20559.1.
AY128901 mRNA. Translation: AAM91301.1.
PIRiT52656.
RefSeqiNP_199995.1. NM_124561.3.
UniGeneiAt.1528.

3D structure databases

ProteinModelPortaliQ9SCY0.
SMRiQ9SCY0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT5G51820.1.

PTM databases

iPTMnetiQ9SCY0.

Proteomic databases

PaxDbiQ9SCY0.
PRIDEiQ9SCY0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT5G51820.1; AT5G51820.1; AT5G51820.
GeneIDi835257.
GrameneiAT5G51820.1; AT5G51820.1; AT5G51820.
KEGGiath:AT5G51820.

Organism-specific databases

TAIRiAT5G51820.

Phylogenomic databases

eggNOGiKOG0625. Eukaryota.
COG0033. LUCA.
HOGENOMiHOG000009550.
InParanoidiQ9SCY0.
KOiK01835.
OMAiNAQEAIP.
OrthoDBiEOG0936067I.
PhylomeDBiQ9SCY0.

Enzyme and pathway databases

BioCyciMetaCyc:AT5G51820-MONOMER.
BRENDAi5.4.2.2. 399.
ReactomeiR-ATH-3322077. Glycogen synthesis.
R-ATH-6798695. Neutrophil degranulation.
R-ATH-70221. Glycogen breakdown (glycogenolysis).
R-ATH-70370. Galactose catabolism.
SABIO-RKQ9SCY0.

Miscellaneous databases

PROiQ9SCY0.

Gene expression databases

GenevisibleiQ9SCY0. AT.

Family and domain databases

Gene3Di3.30.310.50. 1 hit.
3.40.120.10. 3 hits.
InterProiIPR005844. A-D-PHexomutase_a/b/a-I.
IPR016055. A-D-PHexomutase_a/b/a-I/II/III.
IPR005845. A-D-PHexomutase_a/b/a-II.
IPR005846. A-D-PHexomutase_a/b/a-III.
IPR005843. A-D-PHexomutase_C.
IPR016066. A-D-PHexomutase_CS.
IPR005841. Alpha-D-phosphohexomutase_SF.
[Graphical view]
PfamiPF02878. PGM_PMM_I. 1 hit.
PF02879. PGM_PMM_II. 1 hit.
PF02880. PGM_PMM_III. 1 hit.
PF00408. PGM_PMM_IV. 1 hit.
[Graphical view]
PRINTSiPR00509. PGMPMM.
SUPFAMiSSF53738. SSF53738. 3 hits.
SSF55957. SSF55957. 1 hit.
PROSITEiPS00710. PGM_PMM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPGMP_ARATH
AccessioniPrimary (citable) accession number: Q9SCY0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 24, 2001
Last sequence update: January 24, 2001
Last modified: November 30, 2016
This is version 124 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.