Reviewed,
UniProtKB/Swiss-Prot Q9SCX8 (PPA17_ARATH)
Last modified
February 9, 2010.
Version 65.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
Customize display | text xml rdf/xml gff fasta |
Names and origin
| Protein names | Recommended name: Purple acid phosphatase 17 EC=3.1.3.2 Alternative name(s): Acid phosphatase type 5 Peroxidase EC=1.11.1.7 | ||||||||
| Gene names |
| ||||||||
| Organism | Arabidopsis thaliana (Mouse-ear cress) [Complete proteome] | ||||||||
| Taxonomic identifier | 3702 [NCBI] | ||||||||
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Arabidopsis |
Protein attributes
| Sequence length | 338 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Function | Metallo-phosphoesterase involved in phosphate metabolism. Has a peroxidase activity. Ref.1 |
| Catalytic activity | A phosphate monoester + H2O = an alcohol + phosphate. Donor + H2O2 = oxidized donor + 2 H2O. |
| Cofactor | Binds 1 iron ion per subunit By similarity. Binds 1 zinc ion per subunit By similarity. |
| Enzyme regulation | Inhibited by phosphate and molibdate. Ref.1 |
| Subunit structure | Homodimer By similarity. |
| Subcellular location | Secreted By similarity. |
| Tissue specificity | Expressed in roots, stems, leaves, flowers and siliques. Ref.2 |
| Induction | By phosphate starvation, during senescence, by ABA, by H2O2, and by salt stress. Ref.1 |
| Sequence similarities | Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Secreted |
| Domain | Signal |
| Ligand | Iron Metal-binding Zinc |
| Molecular function | Hydrolase Oxidoreductase |
| PTM | Glycoprotein |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | cellular phosphate ion homeostasis Ref.1 Inferred from expression pattern. Source: TAIR oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW response to hydrogen peroxide Ref.1Inferred from expression pattern. Source: TAIR |
| Cellular component | extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | acid phosphatase activity Inferred from electronic annotation. Source: EC iron ion bindingInferred from electronic annotation. Source: UniProtKB-KW peroxidase activityInferred from electronic annotation. Source: EC zinc ion bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Signal peptide | 1 – 31 | 31 | Potential | ||||||
| Chain | 32 – 338 | 307 | Purple acid phosphatase 17 | PRO_5000065319 | |||||
Regions | |||||||||
| Region | 253 – 255 | 3 | Substrate binding By similarity | ||||||
Sites | |||||||||
| Active site | 227 | 1 | Proton donor By similarity | ||||||
| Metal binding | 218 | 1 | Zinc By similarity | ||||||
| Metal binding | 253 | 1 | Zinc By similarity | ||||||
| Metal binding | 255 | 1 | Iron By similarity | ||||||
Amino acid modifications | |||||||||
| Glycosylation | 61 | 1 | N-linked (GlcNAc...) Potential | ||||||
Experimental info | |||||||||
| Sequence conflict | 9 | 1 | M → I in AAM61192. Ref.6 | ||||||
| Sequence conflict | 115 | 1 | Q → R in AAM61192. Ref.6 | ||||||
| Sequence conflict | 245 | 1 | G → S in AAM61192. Ref.6 | ||||||
Sequences
| ||||||||||||||||||
References
| « Hide 'large scale' references | |
| [1] | "A type 5 acid phosphatase gene from Arabidopsis thaliana is induced by phosphate starvation and by some other types of phosphate mobilising/oxidative stress conditions." del Pozo J.C., Allona I., Rubio V., Leyva A., de la Pena A., Aragoncillo C., Paz-Ares J. Plant J. 19:579-589(1999) [PubMed: 10504579] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], FUNCTION, ENZYME REGULATION, INDUCTION. Strain: cv. Landsberg erecta. |
| [2] | "Expression patterns of purple acid phosphatase genes in Arabidopsis organs and functional analysis of AtPAP23 predominantly transcribed in flower." Zhu H., Qian W., Lu X., Li D., Liu X., Liu K., Wang D. Plant Mol. Biol. 59:581-594(2005) [PubMed: 16244908] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY. Strain: cv. Columbia. |
| [3] | "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence features of the regions of 4,504,864 bp covered by sixty P1 and TAC clones." Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S. DNA Res. 7:131-135(2000) [PubMed: 10819329] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia. |
| [4] | "Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. Ecker J.R.Science 302:842-846(2003) [PubMed: 14593172] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia. |
| [5] | "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs." Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K. Shinozaki K.Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia. |
| [6] | "Full-length cDNA from Arabidopsis thaliana." Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. |
| [7] | "Purple acid phosphatases of Arabidopsis thaliana. Comparative analysis and differential regulation by phosphate deprivation." Li D., Zhu H., Liu K., Liu X., Leggewie G., Udvardi M., Wang D. J. Biol. Chem. 277:27772-27781(2002) [PubMed: 12021284] [Abstract] Cited for: GENE FAMILY, NOMENCLATURE. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AJ133747 mRNA. Translation: CAC09923.1. AJ243527 Genomic DNA. Translation: CAB63938.1. AY818189 mRNA. Translation: AAV69751.1. AB019230 Genomic DNA. Translation: BAB02702.1. BT003135 mRNA. Translation: AAO24567.1. AK228106 mRNA. Translation: BAF00065.1. AY084629 mRNA. Translation: AAM61192.1. |
| IPI | IPI00546945. |
| RefSeq | NP_566587.1. |
| UniGene | At.22111 At.71032 Rra.13239 Rsa.1107 |
3D structure databases | |
| SMR | Q9SCX8. Positions 43-331. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q9SCX8. |
Proteomic databases | |
| PRIDE | Q9SCX8. |
Genome annotation databases | |
| GeneID | 821047. |
| GenomeReviews | Gene locus AT3G17790 in contig BA000014_GR. |
| KEGG | ath:AT3G17790. |
| NMPDR | fig|3702.1.peg.13974. |
Organism-specific databases | |
| TAIR | At3g17790. |
Phylogenomic databases | |
| eggNOG | KOG2679. |
| InParanoid | Q9SCX8. |
| OMA | QRSKRWN. |
Gene expression databases | |
| ArrayExpress | Q9SCX8. |
| Genevestigator | Q9SCX8. |
Family and domain databases | |
| InterPro | IPR004843. M-pesterase. [Graphical view] |
| Pfam | PF00149. Metallophos. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | PPA17_ARATH | ||||||||
| Accession | Primary (citable) accession number: Q9SCX8 Secondary accession number(s): Q8LFV2 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | PPAP (Plant Proteome Annotation Project) | ||||||||
Relevant documents
| Arabidopsis thaliana Arabidopsis thaliana: entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with


