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Q9SCW1 (BGAL1_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 106. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Beta-galactosidase 1

Short name=Lactase 1
EC=3.2.1.23
Gene names
Name:BGAL1
Ordered Locus Names:At3g13750
ORF Names:MMM17.1
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length847 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.

Subcellular location

Secretedextracellular spaceapoplast Potential.

Tissue specificity

Ubiquitous, at low levels. Ref.6 Ref.7

Sequence similarities

Belongs to the glycosyl hydrolase 35 family.

Contains 1 SUEL-type lectin domain.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

BRL1Q9ZPS91EBI-2293915,EBI-2292728

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3232 Potential
Chain33 – 847815Beta-galactosidase 1
PRO_5000065877

Regions

Domain761 – 84787SUEL-type lectin

Sites

Active site1901Proton donor Potential
Active site2591Nucleophile Potential

Amino acid modifications

Glycosylation4691N-linked (GlcNAc...) Potential

Experimental info

Sequence conflict5121V → L in AAM13196. Ref.4

Sequences

Sequence LengthMass (Da)Tools
Q9SCW1 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 91C13DE26A4CF4AD

FASTA84793,659
        10         20         30         40         50         60 
MGSKPNAMKN VVAMAAVSAL FLLGFLVCSV SGSVSYDSRA ITINGKRRIL ISGSIHYPRS 

        70         80         90        100        110        120 
TPEMWPDLIR KAKEGGLDVI QTYVFWNGHE PSPGKYYFEG NYDLVKFVKL VQQSGLYLHL 

       130        140        150        160        170        180 
RIGPYVCAEW NFGGFPVWLK YIPGISFRTD NGPFKAQMQR FTTKIVNMMK AERLFESQGG 

       190        200        210        220        230        240 
PIILSQIENE YGPMEYELGA PGRSYTNWAA KMAVGLGTGV PWVMCKQDDA PDPIINACNG 

       250        260        270        280        290        300 
FYCDYFSPNK AYKPKMWTEA WTGWFTKFGG PVPYRPAEDM AFSVARFIQK GGSFINYYMY 

       310        320        330        340        350        360 
HGGTNFGRTA GGPFIATSYD YDAPLDEYGL ERQPKWGHLK DLHRAIKLCE PALVSGEPTR 

       370        380        390        400        410        420 
MPLGNYQEAH VYKSKSGACS AFLANYNPKS YAKVSFGNNH YNLPPWSISI LPDCKNTVYN 

       430        440        450        460        470        480 
TARVGAQTSR MKMVRVPVHG GLSWQAYNED PSTYIDESFT MVGLVEQINT TRDTSDYLWY 

       490        500        510        520        530        540 
MTDVKVDANE GFLRNGDLPT LTVLSAGHAM HVFINGQLSG SAYGSLDSPK LTFRKGVNLR 

       550        560        570        580        590        600 
AGFNKIAILS IAVGLPNVGP HFETWNAGVL GPVSLNGLNG GRRDLSWQKW TYKVGLKGES 

       610        620        630        640        650        660 
LSLHSLSGSS SVEWAEGAFV AQKQPLTWYK TTFSAPAGDS PLAVDMGSMG KGQIWINGQS 

       670        680        690        700        710        720 
LGRHWPAYKA VGSCSECSYT GTFREDKCLR NCGEASQRWY HVPRSWLKPS GNLLVVFEEW 

       730        740        750        760        770        780 
GGDPNGITLV RREVDSVCAD IYEWQSTLVN YQLHASGKVN KPLHPKAHLQ CGPGQKITTV 

       790        800        810        820        830        840 
KFASFGTPEG TCGSYRQGSC HAHHSYDAFN KLCVGQNWCS VTVAPEMFGG DPCPNVMKKL 


AVEAVCA 

« Hide

References

« Hide 'large scale' references
[1]"The beta-galactosidases are encoding by a multigene family in Arabidopsis thaliana."
Gy I., Kreis M., Lecharny A.
Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC clones."
Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.
DNA Res. 7:217-221(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[4]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[5]"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K. expand/collapse author list , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 578-847.
Strain: cv. Columbia.
[6]"Apoplastic glycosidases active against xyloglucan oligosaccharides of Arabidopsis thaliana."
Iglesias N., Abelenda J.A., Rodino M., Sampedro J., Revilla G., Zarra I.
Plant Cell Physiol. 47:55-63(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: TISSUE SPECIFICITY.
[7]"Functional genomic analysis of Arabidopsis thaliana glycoside hydrolase family 35."
Ahn Y.O., Zheng M., Bevan D.R., Esen A., Shiu S.-H., Benson J., Peng H.-P., Miller J.T., Cheng C.-L., Poulton J.E., Shih M.-C.
Phytochemistry 68:1510-1520(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: TISSUE SPECIFICITY, GENE FAMILY, NOMENCLATURE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ270297 mRNA. Translation: CAB64737.1.
AP001307 Genomic DNA. Translation: BAB01923.1.
CP002686 Genomic DNA. Translation: AEE75407.1.
AY093197 mRNA. Translation: AAM13196.1.
AK222229 mRNA. Translation: BAD95407.1.
RefSeqNP_187988.1. NM_112225.4.
UniGeneAt.21793.
At.67729.

3D structure databases

ProteinModelPortalQ9SCW1.
SMRQ9SCW1. Positions 33-732.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid5918. 1 interaction.
IntActQ9SCW1. 1 interaction.

Protein family/group databases

CAZyGH35. Glycoside Hydrolase Family 35.

Proteomic databases

PaxDbQ9SCW1.
PRIDEQ9SCW1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT3G13750.1; AT3G13750.1; AT3G13750.
GeneID820584.
KEGGath:AT3G13750.

Organism-specific databases

GeneFarm485. 90.
TAIRAT3G13750.

Phylogenomic databases

eggNOGCOG1874.
HOGENOMHOG000239919.
InParanoidQ9SCW1.
OMAEFGPLEW.
PhylomeDBQ9SCW1.

Enzyme and pathway databases

BioCycARA:AT3G13750-MONOMER.

Gene expression databases

ArrayExpressQ9SCW1.
GenevestigatorQ9SCW1.

Family and domain databases

Gene3D2.60.120.260. 1 hit.
3.20.20.80. 1 hit.
InterProIPR008979. Galactose-bd-like.
IPR019801. Glyco_hydro_35_CS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR001944. Glycoside_Hdrlase_35.
IPR017853. Glycoside_hydrolase_SF.
IPR000922. Lectin_gal-bd_dom.
[Graphical view]
PANTHERPTHR23421. PTHR23421. 1 hit.
PfamPF02140. Gal_Lectin. 1 hit.
PF01301. Glyco_hydro_35. 1 hit.
[Graphical view]
PRINTSPR00742. GLHYDRLASE35.
SUPFAMSSF49785. SSF49785. 3 hits.
SSF51445. SSF51445. 1 hit.
PROSITEPS01182. GLYCOSYL_HYDROL_F35. 1 hit.
PS00435. PEROXIDASE_1. 1 hit.
PS50228. SUEL_LECTIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBGAL1_ARATH
AccessionPrimary (citable) accession number: Q9SCW1
Secondary accession number(s): Q56W18, Q8RWC1
Entry history
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: May 1, 2000
Last modified: June 11, 2014
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names