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Protein

Probably inactive leucine-rich repeat receptor-like protein kinase IMK2

Gene

IMK2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei565ATPPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi543 – 551ATPPROSITE-ProRule annotation9

GO - Molecular functioni

Keywordsi

Molecular functionReceptor
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probably inactive leucine-rich repeat receptor-like protein kinase IMK2
Alternative name(s):
Protein INFLORESCENCE MERISTEM RECEPTOR-LIKE KINASE 2
Gene namesi
Name:IMK2
Ordered Locus Names:At3g51740
ORF Names:T18N14.120
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G51740.
TAIRilocus:2098267. AT3G51740.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini34 – 458ExtracellularSequence analysisAdd BLAST425
Transmembranei459 – 479HelicalSequence analysisAdd BLAST21
Topological domaini480 – 836CytoplasmicSequence analysisAdd BLAST357

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 33Sequence analysisAdd BLAST33
ChainiPRO_000038945734 – 836Probably inactive leucine-rich repeat receptor-like protein kinase IMK2Add BLAST803

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi75N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi196N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi225N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi236N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi300N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi309N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi336N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi357N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi370N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi389N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi408N-linked (GlcNAc...) asparagineSequence analysis1
Modified residuei539PhosphothreonineBy similarity1
Modified residuei618PhosphoserineBy similarity1
Modified residuei636PhosphothreonineBy similarity1
Modified residuei700PhosphothreonineBy similarity1
Modified residuei715PhosphoserineBy similarity1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

PaxDbiQ9SCT4.

PTM databases

iPTMnetiQ9SCT4.
SwissPalmiQ9SCT4.

Expressioni

Tissue specificityi

Expressed in meristems, including roots, vegetative, inflorescence and floral meristems.2 Publications

Gene expression databases

GenevisibleiQ9SCT4. AT.

Interactioni

Protein-protein interaction databases

BioGridi9655. 2 interactors.
STRINGi3702.AT3G51740.1.

Structurei

3D structure databases

ProteinModelPortaliQ9SCT4.
SMRiQ9SCT4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati119 – 142LRR 1Add BLAST24
Repeati143 – 166LRR 2Add BLAST24
Repeati167 – 189LRR 3Add BLAST23
Repeati191 – 212LRR 4Add BLAST22
Repeati215 – 237LRR 5Add BLAST23
Repeati240 – 261LRR 6Add BLAST22
Repeati264 – 286LRR 7Add BLAST23
Repeati288 – 310LRR 8Add BLAST23
Repeati312 – 334LRR 9Add BLAST23
Repeati336 – 358LRR 10Add BLAST23
Repeati360 – 381LRR 11Add BLAST22
Repeati384 – 406LRR 12Add BLAST23
Domaini537 – 808Protein kinasePROSITE-ProRule annotationAdd BLAST272

Domaini

The protein kinase domain is predicted to be catalytically inactive. Lacks the conserved Asp active site at position 661, which is replaced by an Asn residue.

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation

Keywords - Domaini

Leucine-rich repeat, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IHIJ. Eukaryota.
COG0515. LUCA.
COG4886. LUCA.
HOGENOMiHOG000116554.
InParanoidiQ9SCT4.
OMAiENMIHEN.
OrthoDBiEOG0936049J.
PhylomeDBiQ9SCT4.

Family and domain databases

Gene3Di3.80.10.10. 2 hits.
InterProiView protein in InterPro
IPR011009. Kinase-like_dom_sf.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
IPR032675. LRR_dom_sf.
IPR013210. LRR_N_plant-typ.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
PfamiView protein in Pfam
PF13516. LRR_6. 1 hit.
PF13855. LRR_8. 2 hits.
PF08263. LRRNT_2. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
SMARTiView protein in SMART
SM00369. LRR_TYP. 6 hits.
SUPFAMiSSF52058. SSF52058. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS50011. PROTEIN_KINASE_DOM. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9SCT4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNHLYKNPFR IYEISFHFCA SLLLCFLLFS AQAVAGGGGG GHSWDGIVVT
60 70 80 90 100
QANYQALQAI KHELIDFTGV LKSWNNSASS QVCSGWAGIK CLRGQVVAIQ
110 120 130 140 150
LPWKGLGGTI SEKIGQLGSL RKLSLHNNVI AGSVPRSLGY LKSLRGVYLF
160 170 180 190 200
NNRLSGSIPV SLGNCPLLQN LDLSSNQLTG AIPPSLTEST RLYRLNLSFN
210 220 230 240 250
SLSGPLPVSV ARSYTLTFLD LQHNNLSGSI PDFFVNGSHP LKTLNLDHNR
260 270 280 290 300
FSGAVPVSLC KHSLLEEVSI SHNQLSGSIP RECGGLPHLQ SLDFSYNSIN
310 320 330 340 350
GTIPDSFSNL SSLVSLNLES NHLKGPIPDA IDRLHNLTEL NLKRNKINGP
360 370 380 390 400
IPETIGNISG IKKLDLSENN FTGPIPLSLV HLAKLSSFNV SYNTLSGPVP
410 420 430 440 450
PVLSKKFNSS SFLGNIQLCG YSSSNPCPAP DHHHPLTLSP TSSQEPRKHH
460 470 480 490 500
HRKLSVKDVI LIAIGALLAI LLLLCCILLC CLIKKRAALK QKDGKDKTSE
510 520 530 540 550
KTVSAGVAGT ASAGGEMGGK LVHFDGPFVF TADDLLCATA EIMGKSTYGT
560 570 580 590 600
AYKATLEDGN EVAVKRLREK TTKGVKEFEG EVTALGKIRH QNLLALRAYY
610 620 630 640 650
LGPKGEKLLV FDYMSKGSLS AFLHARGPET LIPWETRMKI AKGISRGLAH
660 670 680 690 700
LHSNENMIHE NLTASNILLD EQTNAHIADY GLSRLMTAAA ATNVIATAGT
710 720 730 740 750
LGYRAPEFSK IKNASAKTDV YSLGIIILEL LTGKSPGEPT NGMDLPQWVA
760 770 780 790 800
SIVKEEWTNE VFDLELMRET QSVGDELLNT LKLALHCVDP SPAARPEANQ
810 820 830
VVEQLEEIRP ETEVETETTP FGSGGEGGKD LGSNEE
Length:836
Mass (Da):90,261
Last modified:May 1, 2000 - v1
Checksum:iEAF6C7BD69193361
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL132968 Genomic DNA. Translation: CAB63160.1.
CP002686 Genomic DNA. Translation: AEE78832.1.
AF372978 mRNA. Translation: AAK50115.1.
AY054515 mRNA. Translation: AAK96706.1.
BT006350 mRNA. Translation: AAP21158.1.
FJ708739 mRNA. Translation: ACN59333.1.
PIRiT46070.
RefSeqiNP_190742.1. NM_115033.4.
UniGeneiAt.669.

Genome annotation databases

EnsemblPlantsiAT3G51740.1; AT3G51740.1; AT3G51740.
GeneIDi824337.
GrameneiAT3G51740.1; AT3G51740.1; AT3G51740.
KEGGiath:AT3G51740.

Similar proteinsi

Entry informationi

Entry nameiIMK2_ARATH
AccessioniPrimary (citable) accession number: Q9SCT4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 24, 2009
Last sequence update: May 1, 2000
Last modified: November 22, 2017
This is version 135 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families